Abstract
Transmissibility of the D variant of encephalo-myocarditis virus (EMC-D) was examined. Eight-week-old ICR:CD-1 male mice inoculated with 105 plaque forming units (PFU)/animal of EMC-D intranasally, orally or intraperitoneally showed marked viraemia and prominent pancreatic lesions at 2 days after inoculation (2 DAI), and excreted virus in faeces from 2 to 8 DAI (virus titre:l03-l05 PFU/g). Only a small proportion of control mice housed with EMC-D-inoculated mice for 10 days developed viraemia and pancreatic lesions.