The case of a Greek woman with acute intermittent porphyria (AIP) associated with systemic lupus erythematosus (SLE) is described and the literature on this association is reviewed. The coexistence of these two diseases may be determined by unknown mechanisms or could be fortuitous.
Quilichini R , Guerder A . Systemic lupus erythematosus and acute intermittent porphyria . Nouv Press Med1973; 2: 1074-1074 .
6.
Vittori F , Desaegher JL . Lupus erythemateux disemine et porphyrie aigue intermittente. Association ou coincidence?Sem Hop Paris1977; 53: 1542–1548 .
7.
Rosemarin JI , Nigro EJ , Levere NR , Mascarenhas BR . Systemic lupus erythematosus and acute intermittent porphyria: coincidence or association?Arthritis Rheum1982; 25: 1134–1137 .
8.
Allard SA , Scott JT . Systemic lupus erythematosus and acute intermittent porphyria . Br J Rheumatol1989; 28: 254–256 .
9.
Andersson C , Lithner F . Hypertension and renal disease in patients with acute intermittent porphyria . J Intern Med1994; 236: 169–175 .
10.
Hetherington GW , Jetton RL , Knox JM . The association of lupus erythematosus and porphyria . Br J Dermatol1970; 82: 118–124 .
11.
Allard SA , Charles PJ , Herrick AL , McColl KEL , Scott JT . Antinuclear antibodies and the diagnosis of systemic lupus erythematosus in patients with acute intermittent porphyria . Ann Rheum Dis1990; 49: 246–248 .
12.
Davis MJ , Van der Ploeg DE . Acute porphyria and coproporphyrinuria following chloroquine therapy. A report of two cases . Arch Dermatol1957; 75: 796–800 .
13.
Clemmensen O , Thomsen Kr . Porphyria cutanea tarda and systemic lupus erythematosus . Arch Dermatol1982; 118: 160–162 .
14.
Thadani H , Deacon A , Peters T . Diagnosis and management of porphyria . Br Med J2000; 320: 1647–1651 .
15.
Tan EM , Cohen AS , Fries JF et al. The 1982 revised criteria for classification of systemic lupus erythematosus . Arthritis Rheum1982; 25: 1271–1277 .
16.
Karim MY , Ruiz-Irastorza G , Khamashta MA , Hugues GRV . Update on therapy-thalidomide in the treatment of lupus . Lupus2001; 10: 188–192 .
17.
Linden IH , Steffen CG , Newcomer VD , Chapman M . Development of porphyria during chloroquine therapy for chronic discoid lupus erythematosus . Calif Med1954; 81: 235–238 .
18.
Moore MR , Hift RJ . Drugs in the acute porphyrias— toxicogenetic diseases . Cell Mol Biol1997; 43: 89–94 .
