This paper represents the first systematic effort to describe the historical foundations of radiation hormesis. Spanning the years from 1898 to the early 1940‘s the paper constructs and assesses the early history of such research and evaluates how advances in related scientific fields affected the course of hormetic related research. The present effort was designed to not only address this gap in current knowledge, but to offer a toxicological basis for how the concept of hormetic dose-response relationships may affect the nature ofthe bioassay and its role in the risk assessment process.
3 Calabrese EJ (editor). Biological Effects of Low Level Exposures to Chemicals and Radiation . Proceedings of the First BELLE Conference, April-May, 1991, Amherst, MA. Lewis Publishers: Chelsea, MI, 1992.
4.
4 Calabrese EJ (editor). Biological Effects of Low Level Exposures-Dose Response Relationships . Proceedings of the Second BELLE Conference, April 1993, Crystal City, VA. CRC Press: Boca Raton, FL, 1994.
5.
5 Calabrese EJ (editor). Toxicological Defense Mechanisms and the Shape of Dose-Response Relationships . Proceedings of the Third BELLE Conference, November 1996, Research Triangle Park, NC. Environmental Health Perspectives 1998; 106 (Suppl.1): 275-394 .
6.
6 Liu SZ (editor). Proceedings of the International Symposium on Biological Effects of Low Level Exposures to Radiation and Relataed Agents. Cangchun, China. Princeton Scientific Publishers, Princeton, NJ, 1994.
7.
7 Sugahara T , Sagan LA , Aoyama T (editors). Low Dose Irradiation and Biological Defense Mechanisms . Proceedings of the International Conference on Low Dose Irradiation and Biological Defense Mechanisms. July 12-16, Kyoto, Japann, 1992.
8.
8 Calabrese EJ , Baldwin LA.Chemical hormesis: Its historical foundations as a biological hypothesis . Toxicologic Pathology1999; 27: 195-216 .
9.
9 Calabrese EJ , Baldwin LA.The marginalization of hormesis . ToxicologicPathology1999; 27: 187-194 .
10.
10 Calabrese EJ , Baldwin LA.The dose determines the stimulation (and poison): development of a chemical hormesis database . International Journal of Toxicology1997; 16: 545-559 .
11.
11 Calabrese EJ , Baldwin LA.A quantitatively-based methodology for the evaluation of chemical hormesis . Human and Ecological Risk Assessment1997; 3: 545-554 .
12.
12 Calabrese EJ , Baldwin LA.A general classification of U-shaped dose-response relationships in toxicology and their mechanistic foundations . Human and Experimental Toxicology1998; 17: 353-364 .
13.
13 Southam CM , Erlich J.Effects of extracts of western red-cedar heartwood on certain wood-decaying fungi in culture . Phytopathology1943; 33: 517-524 .
14.
14 Schulz H.Zuhre Lehre von der Arzneiwirdung . Virchows Archivfur Pathologische Anatomie und Physiologiefur Klinische Medizin1887; 108: 423-445 .
15.
15 Schulz H.Uber Hefegifte . Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere1888; 42: 517-541 .
16.
16 Hueppe F.Principles of Bacteriology. Translated from the German by E.O. Jordan , The Open Court Publishing Company: Chicago , 1896.
17.
17 Schober A.Ein Versuch mit Rontgen'schen Strahlen auf Keimpflanzen . Berichte der Deutschen Botanishen Gesellschaft 14, 1896; No.7: 108-110 .
18.
18 Maldiney E , Thouvenin S.De l'influence des rayons X sur la germination . Revue generale de Botanique1898; 10: 81-86 .
19.
19 Perthes G.Versuche ueber den einfluss der Rontgen und Radiumstrahlen auf Zellteilung . Deutsche Med. Wochenschrift Jahr1904; 30: 632-632 .
20.
20 Euler . Uber die heilende Wirkung der Tontgenstrahlen bei abgegrenzten Eiterungen. Veroffentlichungen Gebiete Des Militar Sanitatswesen. Berlin 1906.
21.
21 Koernicke M.Uber die Wirkung von Rontgenstrahlen auf die Keimung und das Wachstum . Berichte der Deutschen Botanishen Gesellschaft1904; 22: 148-155 .
22.
22 Koernicke M.Weitere Untersuchungen uber die Wirkung von Rontgenund Radiumstrahlen auf die Pflanzen . Berichte der Deutschen Botanishen Gesellschaft1905; 23: 324-333 .
23.
23 Guilleminot H.Effets compares des rayons X et du radium sur la cellule [vegetalel. Valeur de l'unite M en physiologie vegetale . Comptes Rendus Academie des Science (Paris)1907; 145: 798-800 .
24.
24 Schmidt HE.Experimentelle Untersuchungen uber die Wirkung kleinerer und grosserer Strahlenmengen auf junge Zellen . Berliner Klin. Wochenschrift1910; 47, No. 21: 972-974 .
25.
25 Wetterer J.Beitrag zur Kenntnis der biologischen Wirkung der Rontgenstrahlen auf das Wachstum der Pflanzen . Fortschritte auf dem Gebiete Roentgenstrahlen1912-1913; 14: 172-172 .
26.
26 Promsy G , Drevon M.Influence des rayons X sur la germination . Revue generale de Botanique1912; 24: 177197 .
27.
27 Schwarz E.Der Wachstumsreiz der Rontgenstrahlen auf pflanzliche [und tierischel Gewebe . Munch. med. Wochenschr. 60, 1913; 39: 2165-2169 .
28.
28 Miege E , Coupe H.De l'influence des rayons X sur la vegetation . Comptes Rendus Academie des Science (Paris) 159, 1914; 4: 338-340 .
29.
29 Koernicke M.Uver die Wirkung verschieden starker Rontgenstrahlen auf Keimung und Wachstum bei den hoheren Pflanzen . Jahrbucher fur wissenschaftliche Botanik1915; 56: 416-430 .
30.
30 Koernicke M.Wirkung der Tontgenstrahlen auf Pflanzen . Fortschritte auf dem Gebiete Roentgenstrahlen 27, 1920; 1: 661-661 .
31.
31 Yamada M.On the effect of Roentgen rays upon seeds of Oryza sativa . Journal of Physical Therapy No. 6, referenced in Journal of the College of Agriculture. Tokyo Imperial University 1917; 8: 2-2 .
32.
32 Nakamura S.Comparative experiments of the effect of X rays . Proceedings of Koto-Kwai No. 111, Japan, 1918; referenced in Journal of the College of Agriculture. Tokyo Imperial University 1923; 8: 2-2 .
33.
33 Sierp A , Robbers F.Uber die Wirkung der Rontgenstrahlen auf das Wachsum der Pflanzen . Strahlentherapie 14, 1923; 3: 538-557 .
34.
34 Lallemand S.Etude de l'action des rayons X sur le developpement des plantes . Archiv D'anatomie, d'histologie et d'embryologie1929; 10: 1-233 .
36 Altmann V , Rokhlin D , Gleikhgevikht E.Uber [den] entwicklungsbeschleunigenden und entwicklungshemmenden Einfluss der Rontgenstrahlen . Fortschritte auf dem Gebiete Roentgenstrahlen1923; 31: 51-62 .
37.
37 Komuro H.Studies in the effect of Rontgen rays upon the development of Vicia faba . Journal of the College of Agriculture, Imperial University, Tokyo1923; 8: 253-292 .
38.
38 Komuro H.Studies on the effect of Roentgen rays upon the germination of Oryza sativa . Botanical Magazine (Tokyo)1924; 38: 1-21 .
39.
39 Czepa A.Das Problem der wachstumsfordernden und funktionssteigernden Rontgen-Radium-Wirkung . Strahlentherapie1924; 16: 913-913 .
40.
40 Martius H.Bohnenversuche an Rontgenstrahlen . Fortschritte auf dem Gebiete Roentgenstrahlen1924; 32: 361-365 .
41.
41 Geller FC.Die Wirkung der Tontgenstrahlen auf jugendliche Organismen . Klin. Wochenschr. 1924; 3: 561-566 .
42.
42 Gambarov GG.The problem of the so-called ‘irritating’ effect of X rays . Vestnik Rentgenol. i Radiol. 1925; 3, 6: 311-323 .
43.
43 Ancel S.Action de faibles doses de rayons X sur des graines seches . Comptes Rendus Societe Biologie1924; 91: 1435-1436 .
44.
44 Breslavets LB.Plants and X-rays. Translation by A. Elbl . A.H. Sparrow (editor). The American Institute of Biological Sciences: Washington , 1946.
45.
45 Iven H.Neuere Untersuchungen uber die Wirkung der Tontgenstrahlen auf Pflanzen . Strahlentherapie 19, 1925; 3: 413-461 .
46.
46 Ancel S.Les rayons X appliques sur des graines seches n'ont aucune influence sur l'epoque d'apparition du germe . Bulletin Societe Botanique de France1925; 72: 195-197 .
47.
47 Ancel S.Sur un phenomene de pseudo-excitation determine par les rayons X sur les bourgeons dormants cotyledonaires de la Lentille . Bulletin Societe Botanique de France1925; 72: 1084-1088 .
48.
48 Kol'tsov AV , Kol'tsov LI.The influence of radium emanations and X-rays on the growth and development of plants . Zapiski Leningr, Sel'skokhoz. Institute1925; 2: 205-222 .
49.
49 Ancel S.Recherche du meilleur test de la radio reaction des graines des Legumineuses . Bulletin Societe Botanique de France1926; 73: 71-73 .
50.
50 Ancel S.De l'influence accelatrice des rayons X sur le developpement des plantes . Archives de Physiologiques et Biologie1926; 5: 106-118 .
51.
51 Bersa E.Strahlenbiologische Untersuchungen. I. Zur Frage der Rontgenreizwirkung bei Keimlingen . Sitzungsbericgte Akademie der Wissenschaften In Wien, Mathematische-Naturwissenschaftliche Klasse Abt. 1, 135, 1926; 1: 425-451 .
52.
52 Johnson E.Effect of X rays on growth, development and oxidizing enzymes of Helianthus annuus . Botanical Gazette1926; 82: 373-402 .
53.
53 Johnson E.Growth and germination of sunflowers as influenced by X rays . American Journal of Botany1928; 15: 65-76 .
54.
54 Doroshenko AV.The influence of X radiation on the length of the vegetative period in plants . Tr. Prikl. Bot., Genet. i Sel. 23, 1929-1930; 2: 511-535 .
55.
55 Sprague H , Lenz M.The effect of X rays on potato tubers for ‘seed.’ Science 69:606.Weber, F. 1922. Fruhtreiben ruhender Pflanzen durch Rontgenstrahlen . Biochemische Zeitschrift1929; 128: 495-507 .
56.
56 Patten R , Wigoder S.Effect of X rays on seeds . Nature1929; 123: 606-606 .
57.
57 Cattell W.The effect of X rays on the growth of wheat seedlings . Science1931; 73: 531-533 .
58.
58 Johnson E.On the alleged stimulating action of X rays upon plants . American Journal of Botany1931; 18: 603-614 .
59.
59 Johnson E.Effect of X radiation upon growth and reproduction of tomato . Plant Physiology1931; 6: 685-694 .
60.
60 Johnson E.The influence of X radiation on Atriplex hortensis L . New Phytologist1933; 32: 297-307 .
61.
61 Chekhov VP.The influence of X rays on plants . Tr. Tomsk. Gosudarst. Univ. im. V. V. Kuibysheva1932; 85: 67-135 .
62.
62 Shull C , Mitchell J.Stimulative effects of X rays on plant growth . Plant Physiology1933; 8: 287-296 .
63.
63 Benedict HM , Kersten H.Effect of soft X rays on germination of wheat seeds . Plant Physiology1934; 9: 173-178 .
64.
64 Francis DS.The effects of X-rays on growth and respiration of wheat seedlings . Bulletin of the Torrey Botanical Club1934; 61: 119-153 .
65.
65 Breslavets LP , Afanas'eva AS.Increase of yield under the influence of X rays. Rye. II. Irradiation of seeds . Tr. Vsesosoyuznyi Institut Udobrenii Agropochvovedeniya I Agrotekhniki1935; 8: 245-253 .
66.
66 Breslavets LP , Afanas'eva AS.The action of X rays on rye. II, Irradiation of seeds . Vestnik Rentgenol. I Radiol. 1935; 14: 302-324 .
67.
67 Long T , Kersten, H.Stimulation of growth of soy bean seeds by soft X rays . Plant Physiology1936; 11: 615-621 .
68.
68 Frolov G.The action of X rays and ultraviolet rays on the growth of plants . Tr. Sel'skokhoz. Akad. Im. Timiryazeva 1,x 1936; 2: 189-206 .
69.
69 Johnson E.Effects of X rays upon green plants. In: Biological Effects of Radiation. BM Duggar (ed). 2. pp. 961-985. McGraw-Hill: New York , 1936.
70.
70 Saeki H.Studies on the effects of X-ray radiation upon germination, growth and yield of rice plants . Journal of the Society of Tropical Agriculture [Taiwan]1936; 8: 28-38 .
71.
71 Zankevich E , Brunst V.The influence of X rays on the individual development of tobacco, poppies, flax, and rhubarb . Inst. Bot. AN UkSSR, 1937; 10/18: 77-98 .
72.
72 Bless AA.Effects of X-rays on seeds . Plant Physiology1938; 13: 209-211 .
73.
73 Zaurov EI.An experiment on the effect of X rays on Indian hemp . Biologii Zhurnal1937; 6: 479-486 .
74.
74 Breslavets LB.The present status of X-ray biology of plants. Byull. Moskov. Obshchestva Ispytatelei Prirody . Otdel biol. 1937; 46: 359-369 .
75.
75 Wort DJ.X-ray effects on the growth and reproduction of wheat . Plant Physiology1941; 16: 373-383 .
76.
76 Porter TM.The Rise of Statistical Testing, 1820-1900. Princeton University Press: Princeton, NJ , 1986.
77.
77 Hudson JC.Roentgen-Ray Dosimetry. In: O. Glasser , The Science of Radiology. Charles C. Thomas: Springfield, IL . Pp. 120-139, 1933.
78.
78 Taliaferro WH , Taliaferro LG. 1951. Effect of X-rays on immunity: A review . Journal of Immunology1951; 66: 181-212 .
79.
79 Pfeiffer T , Simmermacher W.The influence of Rontgen rays on the seeds of Vicia faba as shown in the development of the plants . Landwirtschaftlichen Versuchs-Stationen1915; 86: 35-43 .
80.
80 Jungling O . Die praktische Verwendbarkeit der Wurzelreaktion von Vicia faba equina zur Bestimmung der biologischen Wertigkeit [der Rontgenstrahlen] . Munch. med. Wochenschr. 1920; 40: 1141-1144 .
81.
81 Johnson E.Susceptibility of seventy species of flowering plants to X radiation . Plant Physiology1936; 11: 319-342 .
82.
82 Stebbing ARD.A theory for growth hormesis . BELLE Newsletter1997; 6: 1-11 .
83.
83 Smith EC.Effects of ultra-violet radiation and temperature on Fusarium. II. Stimulation . Bulletin of the Torrey Botanical Club1935; 62: 151-164 .
84.
84 Smith EC.The effects of radiation on fungi. In: Biological Effects of Radiation, Vol. II. Duggar BM (ed) pp. 889-918. McGraw-Hill Book Co., Inc.: NewYork . 1936.
85.
85 Seide J. 1929.
86.
86 Failla G , Henshaw PS.The relative biological effectiveness of X-rays and gamma rays . Radiology1931; 17: 1-43 .
87.
87 Sax K.The effect of ionizing radiation on plant growth . American Journal of Botany1955; 42: 360-364 .
88.
88 Sax K.The stimulation of plant growth by ionizing radiation . Radiation Botany1963; 3: 179-186 .
89.
89 Packard C.Roentgen radiations in biological research . Radiology1945; 45: 522-533 .
90.
90 Clark AJ.Handbook of Experimental Pharmacology. Verlig Von Julius Springer: Berlin , 1937.
91.
91 Gager CS.Effects of the rays of radium on plants . Memoires of the New York Botanical Garden1908; 4: viii+278-viii+278 .
92.
92 Gager CS.Present status of the problem of the effect of radium rays on plant life . Memoires of the New York Botanical Garden1915; 6: 153-160 .
93.
93 Gager CS.The effects of the rays of radium on plants. In: Biological Effects of Radiation, Vol. II. BM. Duggar (ed) pp. 987-1013. McGraw-Hill Book Co.: New York , 1936.
94.
94 Ewart AJ.Journal of the Department of Agriculture, Victoria1912; 10: 417-421 .
99 Stoklasa J.Influence du selenium et du radium sur la germination des grains . Comptes Rendus Academie des Science (Paris)1922; 174: 1075-1077 .
100.
100 Stoklasa J et al. Die Dynamik der physiologischen Wirkung der Radioaktivitat auf das Protoplasma . Beitrage zur Biologie der Pflanzen1930; 18: 185-224 .
101.
101 Stoklasa J , Penkava J.Biologie des Radiums und Uraniums. Paul Parey: Berlin , 1932.
102.
102 Stoklasa J.Bedeutung der Radioaktivitat in der Physiologie . Chemische Zeitschrift1913; 37: 1176-1176 .
103.
103 Stoklasa J.Bedeutung der Radioaktivitat in der Physiologie . Centralblatt fur Bakteriologie 2. Abt. 1914; 40: 266-280 .
104.
104 Kotzareff A , Chodat F.De l'action exercee par l'emanation du radium sur les levures . Compte Rendu Societe de Physique et d'Histoire Naturelle de Geneve1923; 40: 36-39 .
105.
105 Doumer E. Radiumenanation und die Keimung der Samen. Beiblatter, VI. Internat. Kongress Allgem. Und Arztl. Elektrol. und Radiol. Prog., 1912.
106.
106 Agulhon H , Robert T.The action of radium and radioactivity on germination in the higher plants . Annales de l'Institut Pasteur, Paris1915; 29: 261-273 .
107.
107 Montet D.Action des faibles radioactivities sur la germination des graines . Comptes Rendus Hebdomadaires des Seances de J'Academie des Sciences1932; 194: 304-306 .
108.
108 Montet D.L'action de la radioactivite dur la germination des bulbes . Comptes Rendus Hebdomadaires des Seances de J'Academie des Sciences1932; 194: 1093-1095 .
109.
109 Montet D.De l'influence des faibles radioactivities sur la germination . Comptes Rendus Hebdomadaires des Seances de la Societe Biologie1932; 109: 678-680 .
110.
110 Alexander LT.Radioactive materials as plant stimulantsfield results . Agronomy Journal1950; 42: 252-255 .
111.
111 Lemmermann OG , Schmidt MOC.Die Wirkung von radiumhaltigen Dungemitteln . Zeitschrift fur Pflanzenernahrung, Dungg und Bodenkunde1947; 38: 185-195 .
113 Marx TH , Salm U.Uber die Radioaktivitat und den Dungewert von Plantoradon . Zeitschrift fur Pflanzenernahrung, Dungg und Bodenkunde1947; 38: 195-200 .
114.
114 Gericke S.Dungungsversuche mit Planteondon . Zeitschrift fur Pflanzenernahrung, Dungg und Bodenkunde1948; 42: 143-147 .
115.
115 Baetge HH , Begemann E.Dungungsversuche mit Planteradon . Zeitschrift fur Pflanzenernahrung, Dungg und Bodenkunde1949; 44: 198-206 .
116.
116 Kaindl K , Linser H.Radiation in agricultural research and practice. Developments in the Peaceful Applications of Nuclear Energy No. 10, International Atomic Energy Agency, Karntner Ring, Vienna, Austria , 1961.
117.
117 Linser H , Pelikan W.Gefassversuche mit radioaktiver Dungung . Bodenkultur1951; 5: 417-424 .
118.
118 Kaindl D.Verhalten von Radium in Boden und Pflanze . Bodenkultur1951; 5: 425-436 .
119.
119 Nadson GA , Philippov GS.Action excitante des rayons ultra-violets sur le developpement des levures et des moisissures . Comptes Rendus Societe de Biologie [Paris]1928; 98: 366-368 .
120.
120 Luyet BJ.The effects of ultra violet, X-rays and cathode rays on the spores of Mucoraceae . Radiology1932; 18: 1019-1022 .
121.
121 Schreiber H.Strahlenbiologische Untersuchungen besonders im ultravioletten Spektralbezirk an Saccharomyces turbidans Hansen . Strahlentherapie1934; 49: 541-595 .
122.
122 Chavarria AP , Clark JH.The reaction of pathogenic fungi to ultra-violet light and the role played by pigment in this reaction . American Journal of Hygiene1924; 4: 639-649 .
124 Sperti GS , Loofbourow JR , Lane MM.Effects on tissue cultures of intercellular hormones from injured cells . Science1937; 86: 611-611 .
125.
125 Loofbourow JR.Intercellular hormones. 7. Release of aminoacids by damaged living yeast cells . Biochemical Journal1947; 41: 119-122 .
126.
126 Loofbourow JR , Dwyer CM.Production of intercellular hormones . Nature (London)1939; 143: 725-726 .
127.
127 Loofbourow JR , Morgan MN.Intercellular wound hormones from ultraviolet injured cells . Stud. Inst. Divi Thomae1938; 1: 137-153 .
128.
128 Loofbourow JR. , Cook ES , Stimson MM.Chemical nature of proliferation-promoting factors from injured cells . Nature (London)1938; 142: 573-573 .
129.
129 Loofbourow JR , Cronin AG , Lane MM.Proliferation producing intercellular hormones. I. Quantitative study of factors produced by injured animal tissue cells . Biochemical Journal1940; 34: 432-441 .
130.
130 Loofbourow JR , Englert ME , Dwyer CM.Increased yield of nucleic acid-like substances from irradiated yeast . Nature (London)1941; 148: 113-113 .
131.
131 Loofbourow JR , Oppenheim-Errera S , Loofbourow DG.Intercellular hormones. 8. Release of nucleotides and nucleosides by damaged living cells . Biochemical Journal1947; 41: 122-129 .
132.
132 Loofbourow JR , Webb AM , Abramowitz RK.Relation of aeration to the activity of proliferation promoting action of injured cells . Nature (Lond.)1942; 149: 272-272 .
133.
133 Giese AC.Radiations and cell division . Quarterly Review of Biology1947; 22: 253-282 .
134.
134 Stevens FL.Effects of ultra-violet radiation on various fungi . Botanical Gazette1928; 86: 210-225 .
135.
135 Stevens FL.The sexual stage of fungi induced by ultra-violet rays . Science1928; 67: 514-515 .
136.
136 Stevens FL.The effects of ultra-violet irradiation on various Ascomycetes, Sphaeropsidales and Hyphomycetes . Centralblatt fur Bakteriologie (Abt. 2) 1930; 82: 161-161 .
137.
137 Stevens FL.The ascigerous stage of Colletotrichum lagenarium induced by ultra-violet irradiation . Mycologia1931; 23: 134-139 .
138.
138 Purvis JE , Warwick GR.The influence of spectral colors on the sporulation of Saccharomyces . Proceedings of the Cambridge Philosophical Society1907; 14: 30-40 .
139.
139 Dillon-Weston WAR. III.Studies on the reaction of disease organisms to light. The reaction of disease organisms to certain wave-lengths in the visible and invisible spectrum . Scientific Agronomy1932; 12: 352-356 .
140.
140 Hutchinson AH , Ashton MR.The effects of radiant energy on growth and sporulation in Colletotrichum phomoides . Canadian Journal of Research1930; 3: 187-198 .
141.
141 Ramsey GB , Bailey AA.Effect of ultra-violet radiation on sporulation in Macrosporium and Fusarium . Botanical Gazette1930; 89: 113-136 .
142.
142 Bailey AA.Effects of ultraviolet radiation upon representative species of Fusarium . Botanical Gazette1932; 94: 225-271 .
143.
143 Porter CL , Bockstahler HW.Concerning the reaction of certain fungi to various wave lenghts of light . Proceedings of the Indiana Academy of Sciences1928; 38: 133-135 .
144.
144 Lacassagne A , Holweck F.Sur la radiosensibilite de la levure Saccharomyces ellipsoideus . Comptes Rendus Societe de Biologie [Paris]1930; 104: 1221-1223 .
145.
145 Wycoff RWG , Luyet BJ.The effects of X-rays, cathode and ultra-violet rays on yeast . Radiology1931; 17: 1171-1175 .
146.
146 Zeller H.Wirkung von Arzneimitteln und Strahlen auf Hefe. III. Wirkung von Rontgenstrahlen auf Hefe . Strahlentherapie1926; 23: 336-353 .
147.
147 Fabre G.Effets de l'Activation de l'Atmosphere par l'Emanation de Radium sur la Germination et la Poussee de Divers Organisms Vegetaux . Comptes Rendus Societe de Biologie [Paris]1911; 70: 187-188 .
148.
148 Ingber E.Uber die Radiumsensibilitat des Actinomycespilzes . Strahlentherapie1929; 28: 581-588 .
149.
149 Kayser E , Delaval H.Radioactivite, fixateurs d'azote et levures alcooliques . Comptes Rendus Academie des Science (Paris)1925; 181: 151-153 .
150.
150 Colley MW.Stimulation phenomena in the growth of bacteria as determined by nephelometry . American Journal of Botany1931; 18: 266-287 .
151.
151 Townsend CO.The correlation of growth under the influence of injuries . Annals of Botany1897; 11: 509-532 .
152.
152 Meier FE.Lethal action of ultra-violet light on a unicellular green alga . Smithsonian Miscellaneous Collections1932; 87: 1-11 .
153.
153 Meier FE.Lethal response of the alga Chlorella vulgaris to ultraviolet rays . Smithsonian Miscellaneous Collections1934; 92: 1-12 .
154.
154 Meier FE.Lethal effect of short wave lengths of the ultraviolet on the alga Chlorella vulgaris . Smithsonian Miscellaneous Collections1936; 95: 1-19 .
155.
155 Meier FE.Stimulative effect of short wave lengths of the ultraviolet on the alga Stichococcus bacillaris . Smithsonian Miscellaneous Collections1939; 98: 1-19 .
156.
156 Meier-Chase FM.Increased stimulation of the alga Stichococcus bacillaris by successeive exposures to short wave lengths of the ultraviolet . Smithsonian Miscellaneous Collections1941; 99: 1-16 .
157.
157 Crowther JA.The action of X-rays on Colpidium colpoda . Proceedings of the Royal Society of London, 1926; B100: 390-404 .
158.
158 Markowits E.Cytologische Veranderungen der Einzeller Paramoecium nach Bestrahlung mit Mesothorium . Arch. Zellforsch. 1922; 16: 238-238 .
159.
159 Bovie WT , Hughes DM.The effects of quartz ultra-violet light on the rate of division of Paramecium caudatum . Journal of Medical Research1918; 39: 223-223 .
160.
160 Hinrichs MA.Ultraviolet radiation and division in Paramecium caudatum . Physiological Zoology1928; 1: 394-415 .
161.
161 MacDougall MS.Modification in Chilodon uncinatus produced by ultraviolet radiation . Journal of Experimental Zoology1929; 54: 95-109 .
162.
162 MacDougall MS.Another mutation of Chilodon uncinatus produced by ultraviolet radiation with a description of its maturation processes . Journal of Experimental Zoology1931; 58: 229-236 .
163.
163 Roskin G , Romanowa K.Arzneimittel und ultraviolette Strahlen; die Chininwirkung auf die Zelle bei gleichzeitiger Bestrahlung derselben mit ultravioletten Strahlen . Zeitschrift fur Immunitatforschrung1929; 62: 147-158 .
164.
164 Alpatov NV , Nastiukova DK.The influence of different quantities of ultraviolet radiation on the division rate of Paramecium . C. r. Acad. Sci. USSR1933; 1: 290-291 .
165.
165 Kimball RF.The effects of radiation on protozoa and the eggs of invertebrates other than insects. In: Radiation Biology Vol III: Ultraviolet and Related Radiations. Hollander A (ed). McGraw-Hill Book Company, New York . Pp. 285-331,1955.
166.
166 Chase HY.The effect of ultraviolet light upon early development in the egg of Urechis caupo . Biological Bulletin1937; 72: 377-383 .
167.
167 Chase HY.The effect of ultraviolet light upon cleavage in certain marine eggs . Biological Bulletin1938; 75: 134-144 .
168.
168 Davey WP.The effect of X-rays on the length of life of Tribolium confusum . Journal of Experimental Zoology1917; 22: 573-592 .
169.
169 Davey WP.Prolongation of life of Tribolium confusum apparently due to small doses of X-rays . Journal of Experimental Zoology1919; 28: 447-458 .
170.
170 Cork JM.Gamma radiation and longevity of the flour beetle . Radiation Research1957; 7: 551-557 .
171.
171 Gilman PK , Baetjer FH.Some effects of the rontgen rays on the development of embryos . American Journal of Physiology1904; 10: 222-224 .
172.
172 Essenberg JM.Effect of X-rays on the incubation period, sexual development, and egg-laying in white and brown leghorn chickens . Poultry Science1935; 14: 284-284, 293-293, 317-317 .
173.
173 Bless AA , Romanoff AL.The effect of X-ray stimulation on the bioelectric potentials of the avian egg . Proceedings of the National Academy of Science1942; 28: 306-311 .
174.
174 Bless AA , Romanoff AL.Stimulation of the development of the avian embryo by X-rays . Journal of Cellular and Comparative Physiology1943; 21: 117-121 .
175.
175 Brunst VV.Influence of local X-ray treatment on the development of extremities of the young axolotl (Siredon mexicanum) . Journal of Experimental Zoology1950; 114: 1-49 .
176.
176 Brunst VV.Histopathology of roentgen death of young axolotl (Siredon mexicanum) . American Journal of Roentgenology1957; 78: 518-545 .
177.
177 Brunst VV.Effects of ionizing radiation on the development of amphibians . The Quarterly Review of Biology1965; 40: 1-66 .
178.
178 Caspari W.Physiologie der Rontgen und Radiumstrahlen . Handbuch der norm. und pathol. Physiologie1926; 17: 343-390 .
179.
179 Strelin GS.Rontgenologische Untersuchungen an Hydren II. Die histologischen Veranderungen im Korperbau vom Pelmatohydra oligactis unter der Wirkung der Rontgenstrahlen und ihre Bedeutung fur die Regeneration und Vermehrung . Wilhelm Roux’ Archiv fur Entwicklungsmechanik1929; 115: 27-57 .
180.
180 Zawarzin AA.Rontgenologische Untersuchungen an Hydren I. Die Wirkung der Rontgenstrahlen auf die Vermehrung und Regeneration bei Pelmatrohydra oligactis . Wilhelm Roux’ Archiv fur Entwicklungsmechanik1929; 115: 1-26 .
181.
181 Scheremetjewa EA , Brunst VV.Untersuchung des Einflusses von Rontgenstrahlen auf die Regeneration des Schwanzes bei den Kaulquappen von Pelobates fuscus . Wilhelm Roux’ Archiv fur Entwicklungsmechanik1933; 130: 771-791 .
182.
182 Brunst VV , Scheremetjewa EA.Untersuchung des Einflusses von Rontgenstrahlen auf die Regeneration der Extremitaten beim Triton . Wilhelm Roux’ Archiv fur Entwicklungsmechanik1933; 128: 181-215 .
183.
183 Gordon MB.The stimulative effect of roentgen rays upon the glands of internal secretion . Endocrinology1930; 14: 411-437 .
184.
184 Gordon MB.The stimulative effect of roentgen rays upon the glands of internal secretion . Radiology1931; 17: 1309-1311 .
185.
185 Freund L.Elements of General Radiotherapy (English translation). New York, Rebman Co.: New York , 1904.
186.
186 Borak J.Theories on the effectiveness of roentgen therapy in inflammatory conditions . Radiology1944; 42: 249-254 .
187.
187 Chen W.The laboratory as business: Sir Almroth Wright's vaccine programme and the construction of penicillin. In: The Laboratory Revolution in Medicine. Cunningham, A. and Williams, P. (eds) Cambridge University Press: London , 1992.
188.
188 Heidenhain L , Fried C.Rontgenstrahlen und Entzundung . Klin. Wchnschr. 1924; 3: 1121-1122 .
190 Hartley P.Effect of radiation on production of specific antibodies . Journal of Experimental Pathology1924; 5: 306-313 .
191.
191 Hektoen L.Influence of the X-ray on production of antibodies . Journal of Infectious Diseases1915; 17: 415-422 .
192.
192 Hektoen L.Further studies on the effects of roentgen ray on antibody-production . Journal of Infectious Diseases1918; 22: 28-33 .
193.
193 Westman A.Studies on influence of roentgen and radium rays on phagocytosis . Acta Radiology1923; 2: 57-69 .
194.
194 Castellino PG.L'azione dell'irradiazioni roentgen ed ultraviolette sul sistema reticulo, istiocitario cutaneo . Arch. di radiol. 1930; 6: 681-689 .
195.
195 Tannenberg J , Bayer L.Der heilungavorgang von entzundlichen Veranderungen unter dem Einfluss von Rontgenstrahlen . Strahlentherapie1933; 47: 408-425 .
196.
196 Pendergrass EP , Hodes PJ.Roentgen irradiation in the treatment of inflammations . American Journal of Roentgenology and Radium Therapy1941; 45: 74-106 .
197.
197 Desjardins AU.Radiotherapy for inflammatory conditions . Journal of the American Medical Association1931; 98: 401-408 .
198.
198 Desjardins AU.The action of roentgen rays or radium on inflammatory processes . Radiology1937; 29: 436-445 .
199.
199 Desjardins AU.Dosage and method of roentgen therapy for inflammatory conditions . Radiology1939; 32: 699-707 .
200.
200 Desjardins AU.Radiotherapy for inflammatory conditions . New England Journal of Medicine1939a; 221: 801-809 .
201.
201 Desjardins AU.The action of roentgen rays on inflammatory conditions . Radiology1942; 38: 274-280 .
202.
202 Heidenhain L.Rontgenbestrahlung und Entzundung . Strahlentherapie1926; 24: 37-51 .
203.
203 Musser JH , Edsall DL.A study of metabolism in leukemia, under the influence of the X-ray . Transactions of the Association of American Physicians1905; 20: 294-323 .
204.
204 Edsall DL , Pemberton R.The use of X-rays in unresolved pneumonia . American Journal of Medical Science1907; 133: 286-297 .
205.
205 Quimby AJ , Quimby WA.Unresolved pneumonia: Successful treatment by roentgen ray . New York Medical Journal1916; 103: 681-683 .
206.
206 Mayou MS.A case of trachoma treated by X-rays . Transactions of the Ophthamology Society of the United Kingdom1902; 22: 95-95 .
207.
207 Mayou MS.The treatment of trachoma by X-rays . Transactions of the Ophthamology Society of the United Kingdom1903; 23: 10-23 .
208.
208 Coyle RR.Odds and ends of X-ray work, including some cases of carbuncle . M. Electrol. and Radiology1906; 7: 139-142 .
209.
209 Dunham K.Treatment of carbuncles by the roentgen ray . American Journal of Roentgenology1916; 3: 259-260 .
210.
210 Ross GG.X-ray treatment of carbuncle of face . Annals of Surgery1917; 66: 99-100 .
211.
211 Richards CE.Some of the less common uses of X-ray therapy . Journal of Radiology1922; 3: 271-273 .
212.
212 Lewis RW.A conservative treatment of carbuncles . Annals of Surgery1923; 78: 649-659 .
213.
213 Hodges FM.The roentgen ray in the treatment of carbuncles and other infections . American Journal of Roentgenology1924; 11: 442-445 .
214.
214 Hodges FM.Roentgen ray in treatment of local inflammations. Cellulitis and carbuncles . Journal of the American Medical Association1925; 85: 1292-1294 .
215.
215 Pordes F.Uber die Natur der Wirkung der Rontgenstrahlen, speziell uber das Verschwinden von Anurie nach Nierenbestrahlung . Wien. Klin. Wchnschr. 1923; 36: 656-637 .
216.
216 Pordes F.Der Mechanismus der Rontgenwirkung: Ein Erklarungsversuch . Fortschritte auf dem Gebiete Roentgenstrahlen1923-1924; 31: 287-297 .
219 Holzknecht G.Roentgen treatment of spontaneous post-traumatic and postoperative coccus infections and suppurations . American Journal of Roentgenology1926; 15: 332-336 .
220.
220 Gerber I.Roentgen-ray treatment of superficial pyogenic infectioms . Rhode Island Medical Journal1926; 9: 33-38 .
221.
221 Fraenkel SR , Nissnjewitsch LM.Ueber die Rontgenbehandlung der chirirgischen entzundlichen Vorgange . Strahlentherapie1926; 24: 87-100 .
222.
222 Solomon S , Blondeau A.La roentgentherapie dans les affections inflammatoires . J. de radiol. et d'electrol. 1927; 11: 465-469 .
223.
223 Carp L.Treatment of carbuncles . Annals of Surgery1927; 86: 702-706 .
224.
224 Light RU , Sosman MC.Treatment of carbuncles by the roentgen ray . New England Journal of Medicine1930; 203: 549-555 .
225.
225 King CO.Radiation therapy of carbuncles . Southern Medical Journal1937; 30: 903-906 .
226.
226 Krost GN.Unresolved pneumonia in choldren; treatment with roentgen ray . American Journal of Diseases of Children1925; 30: 57-71 .
227.
227 Torrey RG.Roentgentherapy in disorders of the respiratory tract, particularly those associated with enlargement or persistence of the thymus gland, and those associated with unresolved pneumonic exudates . S. Clin. N. America1927; 7: 221-235 .
231 Gadjanski B.Ueber die Radiotherapie der akuten Entzundungen . Serb. Arch. f. d. ges. Med. 1927; 4: 191-191 .
232.
232 Glas K.Rontgenbehandlung von Lungenstorungen nach Operationen . Wien. klin. Wehnschr. 1927; 40: 1054-1055 .
233.
233 Holtz L.Ueber die Behandlung der Pneumonie mit Rontgenstrahlen . Ztschr. f. klin. Med. 1929; 109: 698-713 .
234.
234 Merritt EA , McPeak EM.Roentgen irradiation in unresolved pneumonia . American Journal of Roentgenology1930; 23: 45-48 .
235.
235 McIntire FT , Smith JH.X-ray therapy in treatment of pneumonia . Texas State Journal of Medicine1937; 33: 422-426 .
236.
236 Powell EV.Roentgen therapy of lobar pneumonia . Journal of the American Medical Association1938; 110: 19-22 .
237.
237 Powell EV.Treatment if acute pneumonias with roentgen rays . American Journal of Roentgenology and Radium Therapy1939; 41: 404-414 .
238.
238 Stephenson S , Walsh D.Short note on the cure of trachoma by X-ray tube exposure and by high-frequency brush discharges . Lancet1903; 1: 237-237 .
239.
239 Bettremieux . Rayons X en therapeutiqueoculaire . Clin. Opht. 1903; 9: 225-227 .
240.
240 Cassidy HF , Rayne FC.Trachome chronique tres ameliore par les rayons X . Tr. Ann. d'electrobiol. 1903; 6: 617-619 .
241.
241 Geyser AC.The successful treatment of eighteen cases of granular lids by the X-ray and high-frequency vacuum electrodes . American Therapist1903-1904; 12: 41-43 .
242.
242 Geyser AC.The successful treatment of eighteen cases of granular lids by the X-ray and high-frequency vacuum electrodes . Journal of Advanced Therapeutics1904; 22: 299-302 .
243.
243 Pardo R.Due casi di tracoma trattati coi raggi di Rontgen . Gazz. d. osp. 1904; 25: 459-460 .
244.
244 Horniker E , Romanin V.Ueber einen Hulfsapparat zur Behandlung des Trachoms mit Rontgenstrahlen . Ztschr. f. Augenh. 1905; 14: 569-575 .
245.
245 Stargardt K.Ueber die Wirkung der Rontgenstrahlen auf Trachomfollikel . Ztschr. f. Augenh., Ber. 1905; 14: 251-258 .
246.
246 Thielemann R.Zur Wirkungsweise des Radiumbestrahlung auf die trachomatose Bindehaut . Ztschr. f. Augenh. 1905; 14: 559-569 .
247.
247 Newcomet WS.Radium and radioactive salts compared with X-rays . Journal of Advanced Therapeutics1912; 30: 72-77 .
250 Cochard M. La radiotherapie du trachome. Thesis 128. Lyons, France, 1921.
251.
251 Meldolesi G , Sabbadini D.Sulla terapia del con le radiazioni secondarie ottenute col metodo del Ghilarducci . Radiol. med. 1923; 10: 222-222 .
252.
252 Meldolesi G.Sulla terapia del tracoma con le radiazioni secondarie (secondo il metodo del Ghilarducci) . Actinoterapia1924; 4: 97-162 .
253.
253 Lane LA.Radium in ophthalmology, with special reference to its use in benign affections . journal of the American Medical Association1924; 83: 1838-1845 .
254.
254 Sabbadini D.Le modificazioni cliniche ed anatomo-pathologiche della conguintiva tracomatosa in seguito all'azione delle radiazioni secondarie . Arch. di Radio. 1926; 2: 584-688 .
255.
255 Kelly JF.The X-ray as an aid in treatment of gas gangrene . Radiology1933; 20: 296-304 .
256.
256 Kelly JF.Present status of the x-ray as an aid in treatment of gas gangrene . Radiology1936; 26: 41-44 .
257.
257 Hubeny MJ , McNattin RF.X-ray therapy: Evaluation of its use in treatment of diseases of non-malignant neoplastic nature . Urol. and Cutan. Rev. 42: 436-441 .
258.
258 Kelly JF , Dowell DA.Present status of X-rays as aid in treatment of gas gangrene . J.A.M.A. 1936; 107: 1114-1118 .
259.
259 Kelly JF , Dowell DA.Twelve-year review of X-ray therapy of gas gangrene . Radiology1941; 37: 421-439 .
260.
260 Altemeier WA , Jones HC.Experimental peritonitis: Its prevention by X-ray irradiation . Journal of the American Medical Association1940; 114: 27-29 .
261.
261 Bates MT.Gas gangrene; review of 32 cases with special reference to the use of serum, both prophylactic and therapeutic . Annals of Surgery1937; 105: 257-264 .
262.
262 Faust JJ.Radiation therapy of gas bacillus infecton . Illinois Medical Journal1934; 66: 547-551 .
263.
263 Faust nI.Report on x-ray treatments in gas gangrene cases . Radiology1934; 22: 105-106 .
264.
264 Kelly JF , Dowell DA , Russum BC and Colien FE.Practical and experimental aspects of roentgen treatment of Bacillus welchii (gas gangrene) and other gas-forming infections . Radiology1938; 31: 608-619 .
265.
265 Kelly JF , Dowell DA.Roentgen Treatment of Infections. The Yearbook Publishers, Chicago, IL . 432-432 pp. 1942.
