Physical and physicochemical evaluation of calcium phosphate cement made using human derived blood plasma

Abstract

In the present work, calcium phosphate cement was made by mixing a solid phase and blood plasma as liquid phase. The basic properties of the cement (called BPC) were compared with those of conventional calcium phosphate cement (c-CPC) where distilled water was used as liquid. BPC had better consistency and injectability than c-CPC but longer setting time. In both cements, the reactants were converted into apatite phase after immersing in simulated body fluid but the phase formed in BPC had lower crystallinity than the phase formed in c-CPC. The set BPC was stronger than c-CPC, having a compressive strength (CS) of about 2–6 MPa after 24 h incubation at 37°C. The CS reduced during soaking at early stage but was relatively improved at the end of soaking period (day 7). In contrast, an increase in CS was observed in c-CPC during soaking period.