Summary Report of the ADCES 2021 Insulin Initiation and Titration Survey

Association of Diabetes Care and Education Specialists. Diabetes care and education specialists play a critical role in successful insulin management. ADCES Practice Paper. Accessed April 2, 2022. https://www.diabeteseducator.org/docs/default-source/practice/practice-documents/practice-papers/insulin-titration-white-paper-final_2017.pdf

Centers for Disease Control and Prevention. National Diabetes Statistics Report. Accessed April 2, 2022. https:// www.cdc.gov/diabetes/data/statistics-report/index.html

Delgado C Baweja M Crews D , et al. A unifying approach for GFR estimation: recommendations of the NKF-ASN Task Force on reassessing the inclusion of race in diagnosing kidney disease. Am J Kidney Dis. 2022;79(2):268-288.e1. doi:10.1053/j.ajkd.2021.08.003

Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329(14):977-986. doi:10.1056/nejm199309303291401

UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet. 1998;352(9131):837-853. Erratum in: Lancet 199914;354(9178):602. PMID: 9742976. doi:10.1016/s0140-6736(98)07019-6

The Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. New Engl J Med. 2005;353:2643-2653. doi:10.1056/NEJMoa052187

Holman R Paul S Bethel M Matthews D Neil H. 10-year follow-up of intensive glucose control in type 2 diabetes. New Engl J Med. 2008;359(15):1577-1589. doi:10.1056/nejmoa0806470

UK Prospective Diabetes Study Group. U.K. prospective diabetes study 16. Overview of 6 years’ therapy of type II diabetes: a progressive disease. Diabetes. 1995;44(11):1249-1258. Erratum in: Diabetes 1996;45(11):1655. PMID: 7589820. doi:10.2337/diabetes.44.11.1249

Viberti G Kahn S Greene D , et al. A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes. Diabetes Care. 2002;25(10):1737-1743. doi:10.2337/diacare.25.10.1737

American Diabetes Association Professional Practice Committee. 9. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2022. Diabetes Care. 2022;45(suppl 1):S125-S143. doi:10.2337/dc22-S009

Kristensen S Rørth R Jhund P , et al. Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes Endocrinol. 2019;7(10):776-785. doi:10.1016/s2213-8587(19)30249-9

Zelniker T Wiviott S Raz I , et al. SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet. 393(10166):31-39. doi:10.1016/S0140-6736(18)32590-X

Davies M D’Alessio D Fradkin J , et al. Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018;41(12):2669-2701. doi:10.2337/dci18-0033

Funnell M. The Diabetes Attitudes, Wishes, and Needs (DAWN) Study. Clin Diabetes. 2006;24(4):154-155. doi:10.2337/diaclin.24.4.154

Zhang P Zhang H Li X Chen M Wang D Ji L. Factors and outcomes associated with discontinuation of basal insulin therapy in patients with type 2 diabetes mellitus. Endocrinol Diabetes Metab. 2020;3(2):e00122. doi:10.1002/edm2.122

Gabbay R Kendall D Beebe C , et al. Addressing therapeutic inertia in 2020 and beyond: a 3-year initiative of the American Diabetes Association. Clini Diabetes. 2020;38(4):371-381. doi:10.2337/cd20-0053