Sage Journals: Discover world-class research

Abstract

Background:

Cancer patients experience significant changes in their social roles along with various physical and psychological challenges. Despite the growing recognition of the importance of palliative care in Bangladesh, there is a notable gap in research focusing on the psychosocial issues faced by patients with advanced cancer.

Aim:

This study aims to explore the level of social support perceived by Bangladeshi cancer patients and determine how this support relates to their mental health status.

Methods:

This cross-sectional study was conducted among 115 advanced cancer (stages III and IV) patients admitted to the palliative medicine department of a tertiary care hospital in Bangladesh. Perceived social support was measured by the Multidimensional Scale of Perceived Social Support, and the mental health status of the patients was assessed by Depression, Anxiety, and Stress Scale-21. Data collection was done from June to November 2023. Relationships between perceived social support, depression, anxiety, and stress were assessed by the Spearman correlation test. The moderating effect of perceived social support on patients’ mental health variables was determined by multiple linear regression and simple slope analysis. p Value <0.05 was considered to be statistically significant.

Result:

The study included an almost equal number of male (49.6%) and female (50.4%) patients, with a mean age of 50.7 ± 14.4 years. Overall, perceived social support was moderate to high for most (74.7%) of the participants. Among the participants, 78.3% experienced anxiety, 77.4% suffered from depression, and 70.5% experienced stress. Depression, anxiety, and stress were all negatively and significantly (p < 0.05) correlated with perceived social support. Younger patients reported higher levels of anxiety, stress, and depression. Perceived social support had a significant buffering effect on depression and anxiety among the younger patients.

Conclusion:

Perceived social support has a profound and significant effect on the mental health of advanced cancer patients. Integrating psychosocial support early in palliative care can be highly beneficial to the mental health of these patients.

Plain language summary

Social support and mental health of cancer patients

This cross-sectional study was conducted among 115 patients with advanced cancer (stages III and IV) admitted to the palliative medicine department of a tertiary care hospital in Bangladesh. The majority of the patients with advanced cancer suffer from depression and anxiety and experience high level of stress. Younger patients report more of these psychological issues. High level of perceived social support is associated with lower levels of depression, anxiety, and stress. It acts as a buffer against these negative emotions. Patients who experienced a high level of social support while dealing with physical pain reported less depression.

Keywords

anxiety Bangladesh cancer depression social support stress

Background

Health is a multidimensional concept that encompasses not only physical health but also mental, emotional, and social well-being.¹ Cancer and its clinical manifestations, along with its treatment side effects, bring about various changes in the patient’s personal life, daily activities, work, and relationships with their families and friends, as well as in their role in society.² These changes often lead to a huge psychological burden, a high level of stress, reduced compliance with treatment, and increased mortality.^3,4

Among all the mental health issues encountered by advanced cancer patients, anxiety and depression are the most common problems.⁵ Several studies conducted in different countries found that about 16–38% of patients with advanced cancer suffer from clinical depression, 93% report mild- to-moderate levels of anxiety, and 93.6% experience a high level of stress throughout their illness period.^6–11 Aside from psychological issues, these patients are also burdened with various physical symptoms. Among them, pain is one of the most common physical symptoms reported by cancer patients. Almost 35–96% of patients with advanced cancer suffer from pain.¹² These physical and mental health issues are interconnected and influenced by psychosocial variables. Researchers suggested that depression, anxiety, and perceptions of social support influence cancer patients’ degrees of pain interference.¹³ Currently, about 1.3–1.5 million people in Bangladesh are living with cancer, and most of them suffer from significant physical and psychosocial burdens. Our sociocultural context, cultural norms, and stigmas surrounding cancer also influence the illness experience of these patients.^14,15 Studies have demonstrated that social support helps to ease some of the challenges of living with cancer.¹⁶

Perceived social support is a crucial factor that affects the physical and psychological well-being of cancer patients. It also plays a significant role in determining their quality of life during the advanced stage of the disease.¹⁷ Perceived social support refers to ‘how an individual perceives friends, family members, and others as sources available to provide material, psychological, and overall support during times of need’.¹⁸ According to Cohen and Wills’ stress buffer theory, social support protects (i.e. buffers) people from the adverse effects of stress.¹⁹ Another model suggests that patients who perceive high social support have lower levels of depression.²⁰ One study demonstrated a negative association between perceived social support and anxiety symptoms, which indicates a high level of social support can alleviate anxiety.²¹ Although the direct relationship between perceived social support, mental health issues, and pain is not often explored, one study found that a higher level of social support is linked to less pain and depressive symptoms.²² All of these models are above and beyond the effects of covariates such as age, cancer stage, treatment modalities, performance status, and use of antidepressant and pain medications. However, many studies have also suggested that age is an important factor influencing the mental health status of cancer patients, specifically depression and anxiety. Despite this, there is not enough literature available exploring the direct relationship between age and psychosocial variables.^11,23,24

Palliative care services in Bangladesh have evolved over the years but remain limited in availability and accessibility, especially outside urban centers. Furthermore, the challenges faced by cancer patients and their families are compounded by socioeconomic disparities and limited access to healthcare services. Therefore, it is crucial to understand the significance of social support and mental health issues in this context. An observational study found significant physical, psychosocial, and spiritual burdens among Bangladeshi patients with advanced incurable illnesses. Although their families and friends provide some practical support, only a few patients have access to any professional support for these concerns.¹⁵ Despite these challenges, palliative care providers in Bangladesh play a crucial role in addressing the complex needs of patients with advanced cancer, including pain management, symptom control, and psychosocial support. A study conducted in a community-based palliative care center in Bangladesh showed a significant reduction of pain and other symptoms among cancer patients, in addition to a significant improvement in their quality of life.²⁵

Despite the growing recognition of the importance of palliative care in Bangladesh, there is a notable gap in research focusing on the psychosocial issues faced by advanced cancer patients. In addition, the relationship between perceived social support and physical and psychological issues, which is particularly important for determining the need for further psychosocial aspects of palliative care interventions, remains unexplored. The purpose of this study is to fill the knowledge gap by investigating the level of social support that patients with advanced cancer in Bangladesh perceive. Additionally, the study aims to determine how this support is related to their mental health and physical symptoms like pain.

Methods

Study design and setting

This cross-sectional study was conducted among advanced cancer patients admitted to the Department of Palliative Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka. Data collection was done from June to November 2023.

Sample criteria

Patients with stage III and IV cancers, above 18 years of age, admitted to the Department of Palliative Medicine, BSMMU, were included in the study. Patients with cognitive impairment (mini mental score <24) were excluded from this study.²⁶

Sample size

In a Turkish study, the mean perceived social support among cancer patients was reported at 24.6 ± 5.1 on the Multidimensional Scale of Perceived Social Support (MSPSS) scale.²³ We considered this score as a reference to calculate our sample size using a one-sample proportion test with absolute precision.

Formula

n = \frac{{(u + v)}^{2} σ^{2}}{{(μ - μ_{0})}^{2}}

Here,

n = sample size; u = 1.96 for 5% level of significance; v = 0.84 (constant); µ = 24.6 (the mean perceived social support); σ = 5.1 (SD); µ₀ = 23 (considered deviation in our study finding).

Calculation,

n = \frac{{(1.96 + 0.84)}^{2} \times 5 . 1^{2}}{{(24.6 - 23)}^{2}} = 81

According to this formula, the required minimum sample size was 81. To increase the power of the study, we initially approached 130 patients. Among them, eight patients refused to give informed consent, two withdrew themselves as they were feeling sick, and five were unable to complete the questionnaire. So, our final sample size was 115.

Data collection instruments

Data were collected using a structured questionnaire. It contained questions related to socio-demographic and disease-related information, pain, perceived social support, and mental health-related variables.

Pain was measured by a numerical rating scale. It is a continuous scale ranging from 0 (no pain) to 10 (the worst possible pain experienced). This scale also divides pain into three categories based on intensity: mild (1–3), moderate (4–6), and severe (7–10).²⁷

The mental health status of the patients was assessed by the validated Bangla version of the Depression, Anxiety, and Stress Scale-21 (DASS 21), developed by Lovibond and Lovibond²⁸ (α = 0.74) and translated and validated in Bangla by Alim et al.²⁹ (α = 0.987), a set of three self-report scales designed to measure the emotional states of depression, anxiety, and stress.^28,29 It contains a total of 21 items, 7 for each subscale (depression, anxiety, and stress). Each question is measured on a 4-point Likert scale (range 0–3). It can be interpreted as both continuous and categorical scale. Based on the scoring, each subscale is divided into five categories: normal, mild, moderate, severe, and extremely severe.²⁸

The perceived social support of the patients was measured by the validated Bangla version of the MSPSS, developed by Zimet et al.³⁰ (α = 0.88) and translated and validated in Bangla by Islam³¹ (α = 0.839). It is a quick self-report measure with 12 items, 4 for each of the independent subscales of ‘family’, ‘friends’, and ‘significant others’, to assess support from each of these groups. Each question is measured by a 7-point Likert scale (1–7) ranging from very strongly disagree to very strongly agree. It can also interpreted as both continuous and categorical scale. Based on the scoring total support is divided into three categories: low, medium, and high levels of perceived social support.³⁰

Patient recruitment and data collection procedure

The patients were recruited via a consecutive sampling method. At first, Mini Mental State Examination (MMSE) was done to determine the cognitive state of the patients. If a patient scored ⩾24 on the MMSE scale, then he or she was considered eligible for the study.

At first, the questionnaire was pre-tested among 10 cancer patients. During the pre-testing phase, many participants were confused by the term ‘significant others’ mentioned in the MSPSS questionnaire. To clear up this confusion, we provided an explanation for the term based on a definition used in a study conducted in Thailand.³² According to this study, ‘significant others’ refers to special persons who provide social support to the patient outside of friends or family. This group includes individuals such as neighbors, co-workers, colleagues, classmates, doctors, nurses, palliative care assistants, or volunteers. We have incorporated this explanation into the final questionnaire to ensure clarity for all participants.

The members of the research team collected data from the patients through in-person interviews. The primary investigator recorded the most appropriate response on the questionnaire. Sensitive questions were asked privately, and patients were encouraged to write them down if they felt uncomfortable discussing them openly. Each interview lasted 30 minutes to an hour, depending on the patient’s condition. Very frail patients required multiple visits to complete an interview.

Statistical analysis

All statistical analyses were performed using the Statistical Package for the Social Sciences (SPSS) 26 version (IBM Inc., New York, USA). The subscales of MSPSS and DASS 21 were calculated separately. For the MSPSS scale, scores for each subscale were summated separately and divided by 4 to calculate scores for each subscale. For the total score, scores for all subscales were summated and divided by 12. For DASS 21, all scores were multiplied by 2 to calculate the final score.

Categorical variables, such as gender, educational status, economic class, marital status, educational status, primary diagnosis, time since diagnosis, and patient performance status, were presented in frequency and percentage. Continuous variables such as age, annual household income, pain scale, perceived social support scores, and anxiety, stress, and depression scores were presented as mean, SD, median, and range. To improve data triangulation, scores for perceived social support, pain and depression, anxiety, and stress were presented into categories according to the scoring manual. All the skewed data was standardized before analysis.

The Spearman correlation test was used to determine the relationship between perceived social support, depression, anxiety, and stress scores. Multiple linear regression analysis was performed to identify the factors influencing the mental health status of the patients. We examined the continuous scores of DASS 21 and MSPSS for this part of the analysis. A simple slope analysis was done to see the interaction effects of perceived social support and other influencing factors of the mental health variables. All means were calculated at a 95% confidence interval, and p values <0.05 were considered the level of statistical significance. The reporting of this study conforms to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines (Supplemental File 2).

Result

Among the study participants, 49.6% were male and 50.4% were female, with a mean age of 50.7 ± 14.4 years. The majority (91.2%) belonged to lower to lower-middle income groups according to the World Bank Group classification.³³ Cancers of the gastrointestinal system (21.7%) were most prevalent among the participants of this study, followed by cancers of the genitourinary system (18.3%), hepatobiliary system (18.3%), and breast (12.2%). Sixty percent of these patients presented to palliative care within 10 months of diagnosis. The majority (80%) of these patients complained of pain, and among them 60.9% suffered from moderate to severe pain (Table 1).

Table 1.

Socio-demographic and clinical characteristics of the patients (n = 115).

Variables	Frequency (n)	Percentage (%)
Gender
Male	57	49.6
Female	58	50.4
Age (in years)
Mean ± SD (years)	50.7 ± 14.4
Educational status
No formal education	32	27.8
Primary level	27	23.5
Secondary level	42	36.5
Graduation and above	14	12.2
Economic class according to yearly household income (Bangladeshi Taka)*
Low (⩽125,033)	36	31.3
Lower middle (125,143.2–491,870.2)	68	59.1
Upper middle (491,980.4–1,525,183.2)	11	9.6
Median (range)	180,000 (36,000–3,600,108) Bangladeshi Taka
Marital status
Married	94	81.7
Unmarried	4	3.5
Widow/widower	13	11.3
Divorced/separated	4	3.5
Primary sites of cancer
Breast	14	12.2
Gastrointestinal system	25	21.7
Head and neck	9	7.8
Genitourinary system	21	18.3
Hematological	8	7.0
Hepatobiliary system	21	18.3
Respiratory system	6	5.1
Unknown primary	11	9.6
Duration since diagnosis (month)
Up to 5	44	38.3
5–10	25	21.7
>10	46	40.0
Median duration	7 months (ranges: 15 days to 40 months)
Current stage of cancer
III	45	39.1
IV	70	60.9
Pain scores
No pain	23	20.0
Mild	22	19.1
Moderate	33	28.7
Severe	37	32.2
Mean score	6 ± 1.2

According to World Bank Group classification (updated on July 2022).

The level of overall perceived social support was moderate to high for most (74.7%) of the participants, and only 25.3% perceived low level of support. However, 97.4% of the participant perceived moderate-to-high levels of support from their families. The lowest level of support was perceived from friends (53%) (Table 2).

Table 2.

Level of perceived social support among the patients (n = 115).

Level of perceived social support	Frequency (n)	Percentage (%)
Support from family
Low	3	2.6
Moderate	34	29.6
High	78	67.8
Median score (range)	6 (1–7)
Support from friends
Low	61	53.0
Moderate	27	23.5
High	27	23.5
Median score (range)	2.5 (1–7)
Support from significant others
Low	45	39.1
Moderate	33	28.7
High	37	32.2
Median score (range)	3.5 (1–7)
Total perceived social support
Low	29	25.3
Moderate	51	44.3
High	35	30.4
Median score (range)	4.1 (1–7)

The majority of the participants suffered from depression (77.4%), anxiety (78.3%), and stress (70.5%). Among them, 40% of them suffered from severe-to-extremely severe depression, 53.9% of them had severe to extremely severe levels of anxiety, and 45% of them experienced severe to extremely severe levels of stress (Table 3).

Table 3.

Mental health status of the patients (n = 115).

Category	Depression	Anxiety	Stress
Category	Frequency, n (%)
Normal	26 (22.6)	25 (21.7)	34 (29.6)
Mild	14(12.2)	10 (8.7)	11 (9.6)
Moderate	29 (25.2)	18 (15.7)	25 (21.7)
Severe	15 (13.0)	16 (13.9)	24 (20.9)
Extremely severe	31 (27.0)	46 (40.0)	21 (18.3)
Mean score ± SD	18.7 ± 11.2	16.9 ± 10.6	22.03 ± 11.1

Depression, anxiety, and stress were all found to be negatively and significantly (p < 0.05) correlated with family support and total perceived social support. Support from friends and significant others was also negatively correlated with depression (Table 4).

Table 4.

Relationship between of perceived social support and mental health (n = 115).

Variables	Family support	Friend support	Significant others support	Total perceived support
Depression
ρ	−0.5	−0.4	−0.3	−0.5
p-Value	0.01	0.01	0.03	0.001
Anxiety
ρ	−0.4	−0.2	−0.1	−0.5
p-Value	0.01	0.05	0.23	0.001
Stress
ρ	−0.3	−0.2	−0.1	−0.6
p-Value	0.01	0.05	0.14	0.01

Spearman correlation was done. Bold values indicates p value <0.05 which considered as significant.

Multiple linear regression analysis showed that the perceived level of social support was negatively and significantly related with depression, anxiety, and stress, whereas pain severity was positively and significantly related with the depression level of the patients. Younger patients were found to be more depressed, anxious, and stressed. Low perceived social support was associated with more depression, anxiety, and stress. Increased level of pain was also associated with higher levels of depression. The interaction effects among moderating variables showed that depression among patients with pain was significantly influenced by the social support they perceived. Patients with pain perceiving higher social support were found to be less depressed. Depression and anxiety among the younger patients were significantly buffered by the social support they perceived. However, we did not find any significant interaction effect of social support with patients’ age on the stress level (Table 5).

Table 5.

Moderating effect of perceived social support on mental health status (n = 115).

Variables	Standardized coefficients	t	p Value	95% CI for B
Variables	β	t	p Value	Lower bound	Upper bound
Depression
Age	−0.67	−2.27	0.02	−0.98	−0.07
Pain severity	1.41	3.11	0.002	0.06	0.26
Perceived social support	−1.15	−2.86	0.01	−5.62	−2.83
Age × Social support	0.93	1.97	0.05	0.001	0.22
Pain × Social support	−0.99	−2.57	0.01	−3.06	−1.80
Anxiety
Age	−1.03	−3.59	0.001	−1.17	−0.35
Pain severity	0.32	1.14	0.25	−0.73	2.71
Perceived social support	−1.37	−3.53	0.001	−6.31	−4.58
Age × Social support	1.41	3.11	0.002	0.06	0.26
Stress
Age	−0.65	−2.26	0.02	−0.94	−0.06
Perceived social support	−0.99	−2.57	0.01	−4.06	−1.80
Age × Social support	0.67	1.48	0.14	−0.03	0.19

Multiple linear regression was done; interaction effects were assessed by simple slope analysis; all variables were analyzed in continuous form.

Discussion

Cancer is a life-changing disease that affects not only the physical condition of patients but also their mental and social well-being. In this study, we investigated the perceived social support of advanced cancer patients in Bangladesh and its relationship with pain and various psychological issues. To the best of our knowledge, this is the first study to explore this relationship.

In this study, most (74.7%) of the participants perceived moderate-to-high levels of social support. Our finding was mostly similar to Iranian and Turkish studies, where the majority (74.5%) of patients reported perceiving moderate-to-high levels of social support.^34,35 It might be due to the religious and cultural similarities between our country and Iranian and Turkish populations, where people mostly lived in tightly knit communities, and supporting other community members was deeply ingrained in their values.

The majority of our participants perceived the highest level of support from their families. The findings of our study were in line with those of other studies conducted in different regions of the world, including East Asian countries such as China, Middle Eastern countries such as Turkey and Iran, and Western countries such as the United States and Scotland.^36–40 High score on the family support subscale among our patients indicated close familial relationships in Bangladeshi society.

It is interesting to note that in our study, cancer patients perceived the lowest level of social support from their friends. This difference in perception might be due to cultural differences, where Asian and Middle Eastern countries rely more on families for support, whereas in Western countries, both families and friends are considered the main sources of social support.^41,42 Although we did not investigate the reasons behind these differences, our findings suggest that similar to other Asian countries, families are perceived as the main source of social support by Bangladeshi cancer patients.

Perceived social support has a significant impact on psychological issues such as depression, anxiety, and stress, which are commonly experienced by cancer patients. Our research revealed a strong negative correlation between perceived social support and these three psychological issues. Patients who reported higher levels of perceived social support experienced lower levels of depression, anxiety, and stress. Several studies conducted across different countries have also reported similar findings.^10,43,44 This phenomenon can be explained by the stress-buffering hypothesis. According to this hypothesis, perceived social support reduces psychological problems by lowering the sense of threat posed by a situation and increasing the accessibility of help.¹⁹ We also observed a notable negative relationship between family support and anxiety, stress, and depression. This means that high level of family support was associated with lower levels of psychological issues among our study participants. Our findings align with previous studies which suggest that family support is a powerful protective factor against such issues, particularly in Asian communities.^24,45

Age plays a significant role in determining the psychological well-being of cancer patients. We found that younger age was associated with higher depression, stress, and anxiety scores. This finding is supported by three separate studies that have demonstrated an inverse correlation between age and psychological distress. Younger cancer patients may experience higher levels of stress and anxiety due to worrying about their diagnosis and treatment.^11,46,47 However, several studies have reported a higher level of depression among older patients, which contradicts our findings.^23,24 Our research has also shown that social support plays a vital role in reducing depression and anxiety levels among young patients. Specifically, perceived social support can act as a buffer against these negative emotions. Studies suggest that young cancer patients tend to receive a high level of social support from their friends and families, which may help alleviate some of their emotional burden.⁴⁸

Pain was another factor that was significantly associated with the mental health of cancer patients. We observed a direct relationship between pain and depression. Regression analysis showed that an increased level of pain was associated with higher levels of depression among our patients. Other studies also found a strong relationship between pain level, depression, and the functional capacity of cancer patients.⁴⁹ Our study also found a direct buffering effect of perceived social support on pain and depression levels. Patients who perceived a high level of social support while dealing with physical pain had lower levels of depression. Our findings supported the model created by Fisher et al., where higher levels of social support were associated with reduced pain and depressive symptoms.²² A recent study has also demonstrated that perceived social support can help mitigate the negative effects of depression on pain.⁵⁰

Our study findings underscore the significant role of social support in addressing mental health issues among advanced cancer patients. Further research is needed to explore the specific needs for such support in clinical settings and to identify effective methods of implementation. This may include investigating psychosocial interventions, integrating multidisciplinary teams into clinics, and providing support to caregivers.

Limitations

It is important to note that this study has some limitations that need to be considered. First, the research was carried out at only one institute, so the findings may not be generalized. Second, the study was cross-sectional in nature, which means that we were unable to observe any changes in the participants’ perception of social support throughout the course of their illness. In addition, due to this cross-sectional design, temporal relationships between variables could not be determined.

Conclusion

Perceived social support has a profound and significant effect on the mental health of advanced cancer patients. Palliative care professionals can work toward integrating psychosocial support early in their management plan, especially for younger patients with psychological distress. They also need to keep social factors in mind while managing pain and psychological issues among advanced cancer patients.

Supplemental Material

sj-doc-2-pcr-10.1177_26323524241256379 – Supplemental material for Relationship between perceived social support and mental health status of the advanced cancer patients receiving palliative care in Bangladesh

Supplemental material, sj-doc-2-pcr-10.1177_26323524241256379 for Relationship between perceived social support and mental health status of the advanced cancer patients receiving palliative care in Bangladesh by Jheelam Biswas, A. K. M. Motiur Rahman Bhuiyan, Afroja Alam and Mostofa Kamal Chowdhury in Palliative Care and Social Practice

Supplemental Material

sj-docx-1-pcr-10.1177_26323524241256379 – Supplemental material for Relationship between perceived social support and mental health status of the advanced cancer patients receiving palliative care in Bangladesh

Supplemental material, sj-docx-1-pcr-10.1177_26323524241256379 for Relationship between perceived social support and mental health status of the advanced cancer patients receiving palliative care in Bangladesh by Jheelam Biswas, A. K. M. Motiur Rahman Bhuiyan, Afroja Alam and Mostofa Kamal Chowdhury in Palliative Care and Social Practice

Footnotes

Acknowledgements

The authors gratefully acknowledge the contribution of Palash Chandra Banik, Associate Professor, Department of Non-Communicable Diseases, Bangladesh University of Health Sciences, Dhaka for his contribution in data analysis and editing this manuscript.

Declarations

ORCID iD

Jheelam Biswas

Supplemental material

Supplemental material for this article is available online.

References

Svalastog

Donev

Jahren-Kristoffersen

, et al. Concepts and definitions of health and health-related values in the knowledge landscapes of the digital society. Croat Med J 2017; 58: 431–435.

Zabalegui

Sanchez

, et al. Nursing and cancer support groups. J Adv Nurs 2005; 51: 369–381.

Arrieta

Angulo

Nunez-Valencia

, et al. Association of depression and anxiety on quality of life, treatment adherence, and prognosis in patients with advanced non-small cell lung cancer. Ann Surg Oncol 2013; 20: 1941–1948.

Batty

Russ

Stamatakis

, et al. Psychological distress in relation to site specific cancer mortality: pooling of unpublished data from 16 prospective cohort studies. BMJ Clin Res 2017; 356: j108.

Mohamed

Kaur

, et al. Perceived social distress and its association with depression and anxiety in breast cancer patients. PLoS One 2017; 12: e0172975.

Hipkins

Whitworth

Tarrier

, et al. Social support, anxiety and depression after chemotherapy for ovarian cancer: a prospective study. Br J Health Psychol 2004; 9: 569–581

Lueboonthavatchai

. Prevalence and psychosocial factors of anxiety and depression in breast cancer patients. J Med Assoc Thai 2007; 90: 2164–2174.

Watts

Prescott

Mason

, et al. Depression and anxiety in ovarian cancer: a systematic review and meta-analysis of prevalence rates. BMJ Open 2015; 5: e007618.

Traeger

Greer

Fernandez-Robles

, et al. Evidence-based treatment of anxiety in patients with cancer. J Clin Oncol 2012; 30: 1197–1205.

10.

Sheeba

Chako

Sekar

, et al. Correlation between spiritual well-being, Perceived social support and Anxiety among palliative cancer patients. IOSR J Nurs Health Sci 2020; 9: 9–14.

11.

Demirtaş

Temircan

. Examining the relationship between depression, anxiety and stress in kidney cancer patients. J Kidney Cancer VHL 2021; 9: 19–26.

12.

Henson

Maddocks

Evans

, et al Palliative care and the management of common distressing symptoms in advanced cancer: pain, breathlessness, nausea and vomiting, and fatigue. J Clin Oncol 2020; 38: 905–914.

13.

Soares

Biasoli

Scheliga

, et al. Association of social network and social support with health-related quality of life and fatigue in long-term survivors of Hodgkin lymphoma. Support Care Cancer 2013; 21: 2153–2159.

14.

Hussain

SMA

. Comprehensive update on cancer scenario of Bangladesh. South Asian J Cancer 2013; 2: 279–284.

15.

Doherty

Power

Rahman

, et al. The psychosocial and spiritual experiences of patients with advanced incurable illness in Bangladesh: a cross-sectional observational study. Indian J Palliat Care 2019; 25: 487–493.

16.

Pinar

Okdem

Buyukgonenc

, et al. The relationship between social support and the level of anxiety, depression, and quality of life of Turkish women with gynecologic cancer. Cancer Nurs 2012; 35: 229–235.

17.

Pasek

Suchocka

Gąsior

. Model of social support for patients treated for cancer. Cancers 2021; 13: 4786.

18.

Siedlecki

Salthouse

Oishi

, et al. The relationship between social support and subjective well-being across age. Soc Indic Res 2014; 117: 561–576.

19.

Cohen

Wills

. Stress, social support, and the buffering hypothesis. Psychol Bull 1985; 98: 310–357

20.

Zhao

Sun

Yang

. Effects of social support, hope and resilience on depressive symptoms within 18 months after diagnosis of prostate cancer. Health and Qual Life Outcomes 2021; 19: 15.

21.

Liu

, et al. Sense of coherence mediates perceived social support and depressive and anxiety symptoms in cervical cancer patients: a cross-sectional study. BMC Psychiatry 2023; 23: 4792–4795

22.

Fisher

Winger

Miller

, et al. Relationship between social support, physical symptoms, and depression in women with breast cancer and pain. Support Care Cancer 2021; 29: 5513–5521

23.

Tel

Sari

Aydin

. Social support and depression among the cancer patients. Global J Med Res 2013; 13: 1–3.

24.

Leung

Chen

Lue

, et al. Social support and family functioning on psychological symptoms in elderly Chinese. Arch Gerontol Geriatr 2007; 44: 203–213.

25.

Chowdhury

Saikot

Farheen

, et al. Impact of community palliative care on quality of life among cancer patients in Bangladesh. Int J Environ Res Public Health 2023; 20: 6443.

26.

Crum

Anthony

Bassett

, et al. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA 1993; 269: 2386–2391

27.

Breivik

Borchgrevink

Allen

, et al. Assessment of pain. Br J Anesth 2008; 101: 17–24.

28.

Lovibond

. Manual for the Depression Anxiety & Stress Scales. 2nd ed. Sydney, NSW: Psychology Foundation, 1995.

29.

Alim

SAHM

Kibria

SME

lslam

, et al. Translation of DASS 21 into Bangla and validation among medical students. Bangladesh J Psychiatry 2017; 28: 67–70

30.

Zimet

Powell

Farley

, et al. A. Psychometric characteristics of the Multidimensional Scale of Perceived Social Support. J Pers Assess 1990; 55: 610–617.

31.

Islam

. Psychometric properties of the Bangla version of Multidimensional Scale of Perceived Social Support. Psihologija 2021; 54: 363–380.

32.

Wongpakaran

. A revised Thai Multi-Dimensional Scale of Perceived Social Support. Span J Psychol 2012; 15: 1503–1509.

33.

Hamadeh

Rompaey

Metreau

, et al. New World Bank country classifications by income level: 2022–2023, https://blogs.worldbank.org/opendata/new-world-bank-country-classificationsincome-level-2022-2023 (2022, accessed 18 December 2023).

34.

Savabi-Esfahani

Jafari-Mehdiabad

Mokaryan

, et al. Relationship between breastfeeding factors and breast cancer in women referred to Seyed al-Shohada Hospital in Isfahan, Iran. Iran J Nurs Midwifery Res 2016; 21: 622.

35.

Oztunc

Yesil

Paydas

, et al. Social support and hopelessness in patients with breast cancer. Asian Pac J Cancer Prev 2013; 14: 571–578.

36.

Çürük

Kartin

Şentürk

. A Survey of social support and psychosocial compliance in patients with breast cancer. Arch Nurs Pract Care 2020; 6: 13–18.

37.

Faghani

Rahmani

Parizad

, et al. Social support and its predictors among Iranian cancer survivors. Asian Pac J Cancer Prev 2014; 15: 9767–9771.

38.

Sammarco

. Perceived social support, uncertainty, and quality of life of younger breast cancer survivors. Cancer Nurs 2001; 24: 212–219.

39.

Petersen

. Social capital, social support, and quality of life among long-term breast cancer survivors. Berkeley, CA: University of California, Berkeley. 2008, pp. 105–290.

40.

Cheng

Sit

Chan

. Social support and quality of life among Chinese breast cancer survivors: findings from a mixed methods study. Eur J Oncol Nurs 2013; 17: 788–796.

41.

Zebrack

Mills

Weitzman

. Health and supportive care needs of young adult cancer patients and survivors. J Cancer Surviv 2007; 1: 137–145.

42.

Forsythe

Alfano

Kent

, et al. Social support, self-efficacy for decision-making, and follow-up care use in long-term cancer survivors. Psychooncology 2014; 23: 788–796.

43.

Nurasyikin

Ihsani

Zakariahazli Zulkifli

SZS

, et al. Depression, anxiety, stress and perceived social support among breast cancer survivors in Tertiary Hospital in Malaysia. KnE Life Sci 2018; 4: 232.

44.

Roohafza

Afshar

Keshteli

, et al. What’s the role of perceived social support and coping styles in depression and anxiety? J Res Med Sci 2014; 19: 944–949.

45.

Naseri

Taleghani

. Social support and depression in Iranian cancer patients: the role of demographic variables. J Caring Sci 2018; 7: 143–147.

46.

Kornblith

Herndon

Zuckerman

, et al. Social support as a buffer to the psychological impact of stressful life events in women with breast cancer. Cancer 2001; 91: 443–454.

47.

Nausheen

Kamal

. Familial social support and depression in breast cancer: an exploratory study on a Pakistani sample. Psychooncology 2006; 16: 859–862.

48.

Wesley

Zelikovsky

Schwartz

. Physical symptoms, perceived social support, and affect in adolescents with cancer. J Psychosoc Oncol 2013; 31: 451–467.

49.

Azevedo

Pessalacia

JDR

Mata

LRF

, et al. Interface between social support, quality of life and depression in users eligible for palliative care. Rev Esc Enferm USP 2017; 51: e03245.

50.

Galloway

Meadors

Boselli

, et al. Anxiety, depression, pain, and social support in a large representative cancer population. J Clin Oncol 2019; 37(31_suppl): 74–76.

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.04 MB

0.03 MB