The International Psoriasis Council (IPC) is a global nonprofit organization dedicated to advancing psoriasis research and treatment by providing a forum for education, collaboration, and innovation among physicians, researchers, and other professionals interested in psoriasis. Each year, the IPC identifies the top papers in the field of psoriasis. Those selected from the second half of 2010 are reviewed here.
Suárez-FariñasM., Fuentes-DuculanJ., LowesM.A., KruegerJ.G.Resolved psoriasis lesions retain expression of a subset of disease-related genes. J Invest Dermatol.2011; 131(2): 391–400.
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StrangeA., CaponF., SpencerC.C.A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Genetic Analysis of Psoriasis Consortium and the Wellcome Trust Case Control Consortium 2, Nat Genet.2010; 42(11): 985–90.
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GhoreschiK., LaurenceA., YangX.P.Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling. Nature.2010; 467(7318): 967–71.
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RizzoH.L., KagamiS., PhillipsK.G., KurtzS.E., JacquesS.L., BlauveltA.IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A. J Immunol.2011; 186(3): 1495–1502.
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TonelG., ConradC., LaggnerU.Cutting edge: a critical functional role for IL-23 in psoriasis. J Immunol.2010; 185(10): 5688–91.