Purpose: To evaluate prevalence trends of myopia-related retinal detachment (RD) in the United States from 2015 to 2024, with additional stratification by age, sex, and race/ethnicity. Methods: This serial cross-sectional study used the Research USA No Date Shift Network on the TriNetX platform. Using the International Classification of Diseases-10 and Current Procedural Terminology codes, retinal detachment cases were evaluated in a cohort of myopic patients. Retinoschisis, retinal cysts, and retinal breaks without detachment were excluded. Prevalence was stratified by age, sex, and race/ethnicity and reported per 100 000 outpatient visits, excluding patients younger than 10 years or with unknown sex. Prevalence ratios and 95% CIs were calculated. Results: Myopia-related RD prevalence increased from 1539 to 4069 cases per 100 000 from the years 2015 to 2024 (prevalence ratio, 2.64; 95% CI, 2.59-2.70). Male patients had the highest prevalence, with 4887 cases per 100 000, compared with 3561 cases per 100 000 in female patients (prevalence ratio, 2.75; 95% CI, 2.54-2.97) in 2024. Asian patients had the highest prevalence, with 4544 cases per 100 000, while Hispanic/Latino patients had the lowest prevalence at 3085 cases per 100 000 (prevalence ratio, 1.47; 95% CI, 1.39-1.57) in 2024. Patients aged 70 to 79 years had the highest prevalence, at 7550 cases per 100 000 in 2024. All demographic categories experienced an increase in myopia-related RD prevalence during the 10-year period. Conclusions: Our study demonstrated an increase in myopia-related RD prevalence, predominantly affecting White and Asian populations, male patients, and older patients.
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