Introduction: Breast reduction mammoplasty incision patterns vary in benefits and drawbacks. The Wise pattern enables lateral skin resection but leaves medial and lateral scars, while the Vertical pattern yields a smaller scar yet limits lateral skin removal. A novel, Paisley pattern allows lateral skin resection without a medial scar. This study compares postoperative outcomes of the various techniques. Methods: A retrospective chart review of 118 patients undergoing bilateral breast reduction mammoplasty from January 2020 to November 2024 at a single institution was performed. Demographics, comorbidities, operative details, and 60-day complications were collected. Analyses included chi-squared tests, ANOVA, and t-tests. Results: Of 118 patients, 60 (51%) underwent Wise, 44 (37%) Vertical, and 14 (12%) Paisley reductions. The Paisley group had the highest BMI (35.5 ± 5.5), significantly higher than Vertical (31.3 ± 4.4, P = .005) but not Wise (33.8 ± 4.6, P = .204). Operative time was shortest for Paisley (2.47 ± 0.41 h) versus Vertical (3.05 ± 1.06 h) and Wise (4.71 ± 1.97 h), significant between Paisley and Wise (P < .001) and Wise and Vertical (P < .001). Paisley had the highest resection volume (2026.9 ± 780.6 g), greater than Vertical (1137.3 ± 624.7 g, P = .03) and comparable to Wise (1860.1 ± 866.1 g, P = .423). Complication rates were 36.4% Vertical, 21.4% Paisley, and 14.8% Wise; no Paisley patients required revision surgery. Conclusions: The Paisley pattern offers comparable complication and reoperation rates, shorter operative time, and greater resection volume, with technical and aesthetic benefits.