Substance use and antisocial behavior (ASB) are complex and interrelated behaviors. This study identified model trajectory classes defined by concurrent substance use and ASB and examined trajectory associations with emerging adult outcomes. Participants from a high-risk sample of youth (n = 536; 73% male) completed interviews at baseline (mean age = 16.1 years) and follow-up (mean age = 22.6 years). Latent class growth analyses identified five trajectory classes based on alcohol/drug use (AOD) and ASB, namely, dual chronic, increasing AOD/persistent ASB, persistent AOD/adolescent ASB, decreasing drugs/persistent ASB, and resolved. Many individuals (56%) exhibited elevated/increasing AOD, and most (91%) reported ASB decreases. Those associated with the dual chronic class had the highest rates of substance dependence, antisocial personality disorder, and negative psychosocial outcomes. There were no differences in adult role attainment across classes. Conjoint examination of these behaviors provides greater detail regarding clinical course and can inform secondary prevention and intervention efforts.
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