The final clinical session of the British Association of Urological Surgeons (BAUS) annual meeting is the Updates and Highlights session, where the most important advances in the main urological sub-specialities are summarised and presented by sub-specialist experts representing each BAUS section. The aim of the session is to disseminate knowledge on the latest research, new guidelines and changes to general and specialist clinical practice. This paper covers contemporary urological advances as presented at the Liverpool BAUS meeting in June 2018.
MejeanARavaudAThezenasS, et al. Sunitinib alone or after nephrectomy in metastatic renal-cell carcinoma. N Engl J Med2018; 379: 417-427.
2.
MotzerRJTannirNMMcDermottDF, et al. Nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma. N Engl J Med2018; 378: 1277-1290.
3.
PowlesTAlbigesLStaehlerM, et al. Updated European Association of Urology guidelines recommendations for the treatment of first-line metastatic clear cell renal cancer. Eur Urol. Epub ahead of print 7 December 2017. DOI: 10.1016/j.eururo.2017.11.016.
4.
BirtleAJChesterJDJonesR, et al. Results of POUT: A randomized trial of perioperative chemotherapy versus surveillance in upper tract urothelial cancer (UTUC). J Clin Onc2018; 6(Suppl.): 407.
5.
MartinRMDonovanJLTurnerEL, et al. Effect of a low-intensity PSA-based screening intervention on prostate cancer mortality: The CAP randomized clinical trial. JAMA2018; 319: 883-895.
6.
FizaziKTranNFeinL, et al. Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. N Engl J Med2017; 377: 352-360.
7.
JamesNDde BonoJSSpearsMR, et al. Abiraterone for prostate cancer not previously treated with hormone therapy. N Engl J Med2017; 377: 338-351.
8.
SmithMRSaadFChowdhuryS, et al. Apalutamide treatment and metastasis-free survival in prostate cancer. N Engl J Med2018; 378: 1408-1418.
9.
HussainMFizaziKSaadF, et al. Enzalutamide in men with nonmetastatic, castration-resistant prostate cancer. N Engl J Med2018; 378: 2465-2474.
10.
AssafNShahTGaoC, et al. P4-4 MIMIC Study: Does the size and location of ureteric stones have an impact on the effectiveness of medically expulsive therapy in improving spontaneous stone passage in patients presenting with acute ureteric colic?J Clin Urol2018; 11(1S): 40-41.
11.
FinchWArmitageJWithingtonJ, et al. P4-13 Is PCNL changing in the UK – analysis of 9500 cases from the BAUS registry. J Clin Urol2018; 11(1S): 46-47.
12.
RajuJThursbyHMuthoveloeD.P4-15 Fate of the antegrade ureteric stent – an observational study and quality improvement project. J Clin Urol2018; 11(1S): 47-48.
BucciSUmariPRizzoM, et al. Emergency extracorporeal shockwave lithotripsy as opposed to delayed SWL for the treatment of acute renal colic due to obstructive ureteral stone: A prospective randomized trial. Minerva Urol Nefrol2018; 70: 526-533.
15.
BachPRicherATeichmanJ.Short-term external ureter stenting shows significant benefit in comparison to routine double-J stent placement after ureterorenoscopic stone extraction: A prospective randomized trial – the Fast track stent study (FaST). Int J Urol2018; 25: 717-722.
16.
TharwatMElsaadanyMMLashinAM.A randomized controlled trial evaluating sildenafil citrate in relieving ureteral stent-related symptoms. World J Urol2018; 36: 1877-1881.
17.
TaeBSChoSJeonBJ, et al. Does mirabegron relieve ureteric stent-related discomfort? A prospective, randomized, multicentre study. BJU Int2018; 122: 866-872.
18.
BozziniGVerzePArcanioloD, et al. A prospective randomized comparison among SWL, PCNL and RIRS for lower calyceal stones less than 2cm: A multicenter experience: A better understanding on the treatment options for lower pole stones. World J Urol2017; 35: 1967-1975.
19.
TranMSutMCollieJ, et al. Development of a disease-specific ureteral calculus patient reported outcome measurement instrument. J Endourol2018; 32: 548-558.
20.
JoshiHRajaAAbdelmotelebH.P4-8 Urinary stones and intervention quality of life (USIQOL) – development and validation of a comprehensive patients reported outcome measure. J Clin Urol2018; 11(1S): 44.
21.
PucciNDMarchiniGSMazzucchiE, et al. Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: A perspective for disease prevention. Int Braz J Urol2018; 44; 758-764.
22.
TaguchiKUsawachintachitMTzouDT, et al. Micro-costing analysis demonstrates comparable costs for LithoVue compared to reusable flexible fiberoptic ureteroscopes. J Endourol2018; 32: 267-273.
23.
ConstableLCotterillNCooperD, et al. Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial. Trials2018; 19: 131.
24.
ForbesRAliAAbouhajarA, et al. Alternatives to prophylactic antibiotics for the treatment of recurrent urinary tract infection in women (ALTAR): Study protocol for a multicentre, pragmatic, patient-randomised, non-inferiority trial. Trials2018; 19: 616.
25.
BaileyKAbramsPBlairPS, et al. Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men: Study protocol for a randomised controlled trial. Trials2015; 16: 567.
26.
WorthingtonJTaylorHAbramsP, et al. A randomised controlled trial to determine the clinical and cost effectiveness of thulium laser transurethral vaporesection of the prostate (ThuVARP) versus transurethral resection of the prostate (TURP) in the National Health Service (NHS) – the UNBLOCS trial: A study protocol for a randomised controlled trial. Trials2017; 18: 179.
27.
PickardRChadwickTOluboyedeY, et al. Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT. Health Technol Assess2018; 22: 1–102.
KeltieKElneilSMongaA, et al. Complications following vaginal mesh procedures for stress urinary incontinence: An 8 year study of 92,246 women. Sci Rep2017; 7: 12015.
31.
FuscoFAbdel-FattahMChappleCR, et al. Updated systematic review and meta-analysis of the comparative data on colposuspensions, pubovaginal slings, and midurethral tapes in the surgical treatment of female stress urinary incontinence. Eur Urol2017; 72: 567-591.
32.
AmundsenCLKomesuYMChermanskyC, et al. Two-year outcomes of sacral neuromodulation versus onabotulinumtoxin A for refractory urgency urinary incontinence: A randomized trial. Eur Urol2018; 74: 66–73.
33.
RayAFPowellJSpeakmanMJ, et al. Efficacy and safety of prostate artery embolization for benign prostatic hyperplasia: An observational study and propensity-matched comparison with transurethral resection of the prostate (the UK-ROPE Study). BJU Int2018; 122: 270-282.
34.
NICE. Prostate artery embolisation for lower urinary tract symptoms caused by benign prostatic hyperplasia. Interventional procedures guidance [IPG611], https://www.nice.org.uk/guidance/ipg611 (2018, accessed 2 April 2019).
35.
HackettGKirbyMWylieK, et al. British Society for Sexual Medicine Guidelines on the Management of Erectile Dysfunction in Men–2017. J Sex Med2018; 15: 430–457.
MinerMParishSJBillupsKL, et al. Erectile dysfunction and subclinical cardiovascular disease. Sex Med Rev. Epub ahead of print 27 Jan 2018. DOI: 10.1016/j.sxmr.2018.01.001.
38.
De NunzioCLombardoRTemaG, et al. Erectile dysfunction and lower urinary tract symptoms. Curr Urol Rep2018; 19: 61.
39.
KheraMAdaikanGBuvatJ, et al. Diagnosis and treatment of testosterone deficiency: Recommendations from the fourth International Consultation for Sexual Medicine. J Sex Med2016; 13: 1787-1804.
40.
WhooleyMAAvinsALMirandaJ, et al. Case-finding instruments for depression. Two questions are as good as many. J Gen Intern Med1997; 12: 439-445.
41.
KatzJEMolinaMLClavijoR, et al. A phase 2 randomized trial to evaluate different dose regimens of low-intensity extracorporeal shockwave therapy for erectile dysfunction: Clinical trial update. Eur Urol Focus2018; 4: 336-337.
42.
RizkPJKriegerJRKohnTP, et al. Low-intensity shockwave therapy for erectile dysfunction. Sex Med Rev2018; 6: 624-630.
43.
HackettGKirbyMEdwardsD, et al. British Society for Sexual Medicine guidelines on adult testosterone deficiency, with statements for UK practice. J Sex Med2017; 14: 1504–1523.
44.
PayneSFowlerSMundyT.P3-10 Aetiology, presentation and initial evaluation of urethral disease in the United Kingdom. J Clin Urol2018; 11(1S): 35-36.
45.
PayneSFowlerSMundyT.P3-11 Contemporary surgical management of urethral disease in the United Kingdom. J Clin Urol2018; 11(1S): 36-38.
