Microelectronics and microsystem technology have changed our daily lives considerably in the past 50 years. Countless everyday objects contain microelectronic components. In healthcare up to the present, however, it has not been possible to make major alterations in introducing electronics and information technology that would lead to innovative improvements and greater transparency. This paper describes initial steps in diagnostics and oncological therapy including telematic healthcare systems which can, for example, assist patients with cardiovascular diseases and shows, through these areas, how electronics and microsystems technology can contribute to better healthcare.
WolfBMüllerESchwindeA. An ultrastructural morphometric analysis on ultrathin epon and ultrathin cryo-sections of normal human gastric tissue and human gastric cancer. Virchows Arch Pathol Ana J1985; 407: 209–219.
2.
WolfBSchwindeAvon KleistS. Differentiation state specific localization of the carcino embryonic antigen (CEA) cryosections of breast, stomach and lung lesions. Anticancer Res1987; 7: 203–208.
3.
WolfBKrausMBrischweinM. Biofunctional hybrid structures - cell-silicon hybrids for applications in biomedicine and bioinformatics. Bioelectrochem Bioenerg1998; 46: 215–225.
4.
WiestJBrischweinMOttoAM. Cell based assay for label-free, multiparametric, long-term monitoring of cellular vitality. ALTEX2009; 26: 96–96.
5.
BrischweinMGrotheHOttoAM. Möglichkeiten und Grenzen der Mikrosensortechnologie in zellulärer Diagnostik und Pharmascreening. Chemie Ingenieur Technik2005; 77: 55–59.
6.
WolfBBrischweinMGrotheHLab-on-a-chip systems for cellular assays. In: UrbanG (ed.) BioMEMS Series: Microsystems, Vol 16. Dordrecht, The Netherlands: Springer-Verlag, 2006, pp. 269–308.
Geisler T, Ressler J, Harz H, et al. Automated multiparametric platform for high-content and high-throughput analytical screening on living cells. IEEE Trans Autom Sci Eng 2006; 3: 169–176.
10.
Friedrich P, Scholz A, Clauss J, et al. Der Arzt im Gepäck – sensorgestützte telemedizinische Konzepte für Diagnostik und Therapie. In: Jäckel A (ed) Telemedizinführer Deutschland. Bad Nauheim: Medizin Forum AG, 2007, pp. 266–271.
11.
Wolf B, Clauss J, Friedrich P, et al. Telematische medizinische Systeme für die individualisierte und personalisierte Assistenz Teil 1. ntz Fachzeitschrift für Informations- und Kommunikationstechnik, 2009, 62 H.1 14–17.
12.
Spittler T, Handwerker M, Friedrich P, et al. Early recognition of depression at diabetes mellitus with the cognitive medical system COMES®, Poster at: IADIS WWW/Internet 2011, Rio de Janeiro, Brazil, 5–8 November 2011.
13.
Friedrich P, Spittler T, Tübinger S, et al. COMES® ein Konzept zur personalisierten telemedizinischen Assistenz – oder – auf Anruf Arzt. In: Duesberg F (ed) E-Health 2011 Informationstechnologien und Telematik im Gesundheitswesen. Solingen: Medical Future Verlag, 2011, pp.254–260.
14.
Hinderer K-U, Friedrich P and Wolf B. Home care: A telematic rehabilitation exerciser. In: Consumer Electronics Berlin - ICCE Berlin, Berlin, Germany, 3–4 September 2012, pp. 15–18 Berlin: IEEE Conference Publications.
15.
KochK. Untersuchungen zur Früherkennung – Krebs – Nutzen und Risiken, Berlin: Stiftung Warentest, 2005.
