The MitraClip is the first-in-class percutaneous therapy for mitral regurgitation. It is delivered from the femoral vein and can be used for degenerative or functional mitral regurgitation. In Singapore, the device was first approved for use in 2011. This review describes the device and discusses the data supporting its use and the regional experience to date. The MitraClip, given the early experience, should only be used after consideration by Heart Teams and only in appropriately selected patients.
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