12 pazienti portatori di glioblastoma multiforme sono stati sottoposti a chemioterapia con carboplatino mediante somministrazione intra-arteriosa (carotide interna e/o vertebrale) in cicli ripetuti. Gli effetti collaterali sono stati valutati con metodiche cliniche, neurofisiologiche, ematochimiche. I risultati indicano come questa procedura sia sufficientemente ben tollerata, in assenza di tossicità diretta sul SNC, e con una mielotossicità globalmente di grado lieve.
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