The causes of ischemic stroke in the young adult are diverse. Human immunodeficiency virus (HIV) infection-related vasculopathy is usually not included in the list of differential diagnoses. HIV-positive patients may present with acute neurologic dysfunction of different causes, among which cerebral infarction is an uncommon one. Herein, we report a HIV-infected young man who suffered from recurrent ischemic strokes with evidence of cerebral vasculopathy on serial magnetic resonance images.
PintoAN: AIDS and cerebrovascular disease. Stroke27: 538–543, 1996.
2.
BergerJRMoskowitzLFischlM: Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome. South Med J80: 683–686, 1987.
3.
ConnorMDLammieGABellJE: Cerebral infarction in adult AIDS patients: Observations from the Edinburgh HIV Autopsy Cohort. Stroke31: 2117–2126, 2000.
4.
GillamsARAllenEHriebK: Cerebral infarction in patients with AIDS. Am J Neuroradiol18: 1581–1585, 1997.
5.
TippingBde VilliersLWainwrightH: Stroke in patients with human immunodeficiency virus infection. J Neurol Neurosurg Psychiatry: 2007.
6.
BrannaganTH3rd: Retroviral-associated vasculitis of the nervous system. Neurol Clin15: 927–944, 1997.
7.
ScaravilliFDanielSEHarcourt-WebsterN: Chronic basal meningitis and vasculitis in acquired immunodeficiency syndrome. A possible role for human immunodeficiency virus. Arch Pathol Lab Med113: 192–195, 1989.
8.
BagasraOLaviEBobroskiL: Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: Identification by the combination of in situ polymerase chain reaction and immunohistochemistry. Aids10: 573–585, 1996.
9.
CalabreseLHDunaGFLieJT: Vasculitis in the central nervous system. Arthritis Rheum40: 1189–1201, 1997.
10.
KayeBRFainstatM: Cerebral vasculitis associated with cocaine abuse. Jama258: 2104–2106, 1987.
11.
AvivRIBenselerSMDeVeberG: Angiography of primary central nervous system angiitis of childhood: Conventional angiography versus magnetic resonance angiography at presentation. Am J Neuroradiol28: 9–15, 2007.
12.
CalabreseLH: Vasculitis and infection with the human immunodeficiency virus. Rheum Dis Clin North Am17: 131–147, 1991.
13.
ChettyR: Vasculitides associated with HIV infection. J Clin Pathol54: 275–278, 2001.
14.
MoorePM: Diagnosis and management of isolated angiitis of the central nervous system. Neurology39: 167–173, 1989.
15.
PomperMGMillerTJStoneJH: CNS vasculitis in autoimmune disease: MR imaging findings and correlation with angiography. Am J Neuroradiol20: 75–85, 1999.
16.
CalabreseLHFurlanAJGraggLA: Primary angiitis of the central nervous system: Diagnostic criteria and clinical approach. Cleve Clin J Med59: 293–306, 1992.
HarrisENGharaviAEBoeyML: Anticardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet2: 1211–1214, 1983.
19.
HassellKLKressinDCNeumannA: Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men. Blood Coagul Fibrinolysis5: 455–462, 1994.
20.
RubbertABockESchwabJ: Anticardiolipin antibodies in HIV infection: Association with cerebral perfusion defects as detected by 99mTc-HMPAO SPECT. Clin Exp Immunol98: 361–368, 1994.
