MR and CT demonstrate morphological changes in intervertebral disks. However the images do not provide an effective means to document interval changes in the disk due to degeneration, aging or healing. Functional imaging that may assesses the biomechanical or the biochemical integrity of the disk, may provide a measure of changes in the disk over time. To study the biomechanical function of the disk, translation and rotation of spinal vertebrae can be measured with CT or MR as the spine is subjected to a specific load or torque. Biochemical integrity of the disk can be assessed by the estimation of the water content from a measurement of the T2 relaxation time of disk tissue.
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