Preclinical applications in neuroradiology are rapidly growing. This work briefly reviews the aims, methods and research fields in which preclinical neuroradiology units are involved. Specifically we will describe applications in pharmacological research, transgenic animals phenotyping, stem cell imaging and molecular imaging. The interdisciplinary approach, typical of preclinical neuroradiology, appears to be useful also in the training of young neuroradiologists.
MarzolaPOsculatiFSbarbatiA: High field MRI in preclinical research. Eur J Radiol48: 165–70, 2003.
2.
MarzolaPSbarbatiA: Magnetic resonance imaging in animal models of pathologies. Methods Enzymol386: 177–200, 2004.
3.
BeckmannNMuegglerTAllegriniPR. From anatomy to the target: Contributions of magnetic resonance imaging to preclinical pharmaceutical research. Anat Rec265: 85–100, 2001.
4.
BenvenisteHBlackbandS: MR microscopy and high resolution small animal MRI: Applications in neuroscience research. Prog Neurobiol67: 393–420, 2002.
5.
HoehnMKustermannEBlunkJ: Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci U S A.99: 16267–72 (2002).
6.
ModoMMellodewKCashD: Mapping transplanted stem cell migration after a stroke: A serial, in vivo magnetic resonance imaging study. Neuroimage21: 311–7, 2004.
7.
LouieAYHuberMMAhrensET: In vivo visualization of gene expression using magnetic resonance imaging. Nat Biotechnol18: 321–5, 2000.