In the past few years, there have been many exciting advances in the broad discipline of trauma surgery. Recognizing time and space constraints and hoping to avoid duplicate coverage, this review will focus on selected topics not explicitly reviewed by other speakers in this conference. Specifically, we will discuss recent developments in crystalloid resuscitation, recombinant activated factor VII, ultrasound applications in trauma patients, anti-factor Xa levels in thromboprophylaxis, and intensive insulin therapy in trauma patients.
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BoffardKDRiouBWarrenB. Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma. 2005;59:8-15.
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HauserCJBoffardKDuttonR. Results of the CONTROL trial: efficacy and safety of recombinant activated factor VII in the management of refractory traumatic hemorrhage. J Trauma. 2010;69:489-500.
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BlaivasMLyonMDuggalS. A prospective comparison of supine chest radiography and bedside ultrasound for the diagnosis of traumatic pneumothorax. Acad Emerg Med. 2005;12:844-849.
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YanagawaYNishiKSakamotoTOkadaY. Early diagnosis of hypovolemic shock by sonographic measurement of inferior vena cava in trauma patients. J Trauma. 2005;58:825-829.
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YanagawaYSakamotoTOkadaY. Hypovolemic shock evaluated by sonographic measurement of the inferior vena cava during resuscitation in trauma patients. J Trauma. 2007;63:1245-1248.
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GualtieriEDeppeSASipperlyMEThompsonDR. Subclavian venous catheterization: greater success rate for less experienced operators using ultrasound guidance. Crit Care Med. 1995;23:692-697.
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VignonPDugardAAbrahamJ. Focused training for goal-oriented hand-held echocardiography performed by noncardiologist residents in the intensive care unit. Intensive Care Med. 2007;33:1795-1799.
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StawickiSPBraslowBMPanebiancoNL. Intensivist use of hand-carried ultrasonography to measure IVC collapsibility in estimating intravascular volume status: correlations with CVP. J Am Coll Surg. 2009;209:55-61.
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FerradaPMurthiSAnandRJBochicchioGVScaleaT. Transthoracic focused rapid echocardiographic examination: real-time evaluation of fluid status in critically ill trauma patients. J Trauma. 2011;70: 56-62.
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SoldatosTKarakitsosDChatzimichailKPapathanasiouMGouliamosAKarabinisA. Optic nerve sonography in the diagnostic evaluation of adult brain injury. Crit Care. 2008;12:R67.
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SpaniolasKVelmahosGCKwolekCGervasiniADe MoyaMAlamHB. Bedside placement of removable vena cava filters guided by intravascular ultrasound in the critically injured. World J Surg. 2008;32:1438-1443.
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Hernández-SocorroCRMarinJRuiz-SantanaSSantanaLManzanoJL. Bedside sonographic-guided versus blind nasoenteric feeding tube placement in critically ill patients. Crit Care Med. 1996;24: 1690-1694.
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MalinoskiDJafariFEwingT. Standard prophylactic enoxaparin dosing leads to inadequate anti-Xa levels and increased deep venous thrombosis rates in critically ill trauma and surgical patients. J Trauma. 2010;68:874-880.
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van den BergheGWoutersPWeekersF. Intensive insulin therapy in critically ill patients. N Engl J Med. 2001;345:1359-1367.
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PreiserJCDevosPRuiz-SantanaS. A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med. 2009;35:1738-1748.
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BrunkhorstFMEngelCBloosF. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med. 2008;358:125-139.
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AnnaneDCariouAMaximeV. Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA. 2010;303:341-348.
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FinferSChittockDRSuSY. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009;360:1283-1297.
