Phenolic Constituents from Xyloselinum leonidii

Abstract

One new and seven known phenolic compounds were isolated from the twigs of Xyloselinum leonidii, and identified by means of spectroscopic methods. They were identified to be a new hydroxyaetophenone, xyloselin (1) together with four coumarins decursinol (2), decursinol glucoside (3), pteryxin (4), and praeroside I (5), two chromones angelicain (6), and cimifugin (7), and a flavonoid hesperidin (8). Among the isolated compounds, pteryxin showed the strongest inhibitory effect on the nitric oxide production (IC₅₀ = 17.4 μM) while xyloselin showed weak inhibition. The present paper is the first report on the phenolic contents and the anti-inflammatory activity of the genus Xyloselinum.

Keywords

Xyloselinum leonidii Apiaceae Xyloselin Pteryxin Coumarin Chromone

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