Cupolamide B,A Cyclic Heptapeptide from Theonella cupola

Abstract

A new cyclic heptapeptide named cupolamide B (2) was isolated as a minor constituent from the Okinawan sponge Theonella cupola. The structure was elucidated by analyzing spectral data in combination with Marfey analysis of its acid lysate.

Keywords

Sponge Cyclic peptide Nonproteinogenic amino acids

References

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(1984) Determination of D-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzene. Carlsberg Research Communication, 49, 591–596.

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