Two new cucurbitane-type triterpenoids, 7β,23(S)-dimethoxycucurbita-5,24-dien-3β-ol (1) and 3β-hydroxycucurbita-6,23(E),25-trien-5β,19-olide (2), and two known cucurbitane-type triterpenoids, 7β,25-dimethoxycucurbita-5,23(E)-dien-3β-ol (3) and karavilagenin D (4), were isolated from the fruit pulp of Momordica charantia. Their structures were established by means of 1D and 2D NMR spectra (1H, 13C, COSY, HMQC, HMBC, and NOESY) as well as EI-MS data.
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