A new hydroperoxycembranoidal diterpene, trocheliolide A (1), was isolated from the octocoral Sarcophyton trocheliophorum. The structure of 1 was elucidated on the basis of spectroscopic and mass spectrometric methods.
RochaJ, PeixeL, GomesNCM, CaladoR. (2011) Cnidarians as a source of new marine bioactive compounds–an overview of the last decade and future steps for bioprospecting. Marine Drugs, 9, 1860–1886.
2.
LiangLF, GuoYW. (2013) Terpenes from the soft corals of the genus Sarcophyton: chemistry and biological activities. Chemistry & Biodiversity, 10, 2161–2196.
3.
WuYC, HsiehPW, DuhCY, WangSK, SoongK, FangLS. (1992) Studies on the Formosan soft corals I-cytotoxic cembrane diterpenoids from Sarcophyton trocheliophorum. Journal of the Chinese Chemical Society, 39, 355–357.
4.
DuhCY, HouRS. (1996) Cytotoxic cembranoids from the soft corals Sinularia gibberosa and Sarcophyton trocheliophorum. Journal of Natural Products, 59, 595–598.
5.
SuJH, LuY, LinWY, WangWH, SungPJ, SheuJH. (2010) A cembranoid, trocheliophorol, from the cultured soft coral Sarcophyton trocheliophorum. Chemistry Letters, 39, 172–173.
6.
SuJH, AhmedAF, SungPJ, ChaoCH, KuoYH, SheuJH. (2006) Manaarenolides A–I, diterpenoids from the soft coral Sinularia manaarensis. Journal of Natural Products, 69, 1134–1139.
7.
FattorussoE, RomanoA, Taglialatela-ScafatiO, IraceC, MaffettoneC, BavestrelloG, CerranoC. (2009) Oxygenated cembranoids of the decaryiol type from the Indonesian soft coral Lobophytum sp. Tetrahedron, 65, 2898–2904.
AllingerNL. (1977) Conformational analysis. 130. MM2. A hydrocarbon force field utilizing V1 and V2 torsional terms. Journal of the American Chemical Society, 99, 8127–8134.
12.
AlleyMC, ScudieroDA, MonksA, HurseyML, CzerwinskiMJ, FineDL, AbbottBJ, MayoJG, ShoemakerRH, BoydMR. (1988) Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Research, 48, 589–601.
13.
ScudieroDA, ShoemakerRH, PaullKD, MonksA, TierneyS, NofzigerTH, CurrensMJ, SeniffD, BoydMR. (1988) Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Research, 48, 4827–4833.
14.
LuMC, HwangSL, ChangFR, ChenYH, ChangTT, HungCS, WangCL, ChuYH, PanSH, WuYC. (2009) Immunostimulatory effect of Antrodia camphorata extract on functional maturation of dendritic cells. Food Chemistry, 113, 1049–1057.
