Two new indole alkaloids, kopsiyunnanines J1 and J2, were isolated from Yunnan Kopsia arborea, and their structures were determined by spectroscopic analyses. Kopsiyunnanines J1 and J2 are unprecedented Strychnos-type indole alkaloids having an additional C1 unit in the secologanin moiety of the molecule.
KamT, LimK. (2008) Alkaloids of Kopsia. In The Alkaloids, CordellGA (Ed). Academic Press, San Diego, 66, 1–111
2.
AhmadK, HirasawaY, NugrohoAE, HadiAHA, MoritaH. (2012) New aspidofractinine, aspidospermatan and akuamiline indole alkaloids from the roots of Kopsia singapurensis Ridl. Heterocycles, 86, 1611–1619
3.
YangY, ZuoW, ZhaoY, DongW, MeiW, DaiH. (2012) Indole alkaloids from Kopsia hainanensis and evaluation of their antimicrobial activity. Planta Medica, 78, 1881–1884
4.
ChenJ, LiX, LiN, LuJ, XuX, DuanH, QinL. (2012) New indole alkaloid constituents from the stems of Kopsia hainanensis. Chemistry of Natural Compounds, 48, 834–835
ChenJ, ChenJ, YaoX, GaoK. (2011) Kopsihainanines A and B, two unusual alkaloids from Kopsia hainanensis. Organic & Biomolecular Chemistry, 9, 5334–5336
7.
YapW, GanC, LowY, ChooY, EtohT, HayashiM, KomiyamaK, KamT. (2011) Grandilodines A-C, biologically active indole alkaloids from Kopsia grandifolia. Journal of Natural Products, 74, 1309–1312.
8.
SévenetT, AllorgeL, DavidB, AwangK, HadiAHA, Kan-FanC, QuirionJ-C, RemyF, SchallerH, TeoLE. (1994) A preliminary chemotaxonomic review of Kopsia (Apocynaceae). Journal of Ethnopharmacology, 41, 147–183.
9.
KogureN, SuzukiY, WuY, KitajimaM, ZhangR, TakayamaH. (2012) Chemical conversion of strychnine into kopsiyunnanine-I, a new hexacyclic indole alkaloid from Yunnan Kopsia arborea. Tetrahedron Letters, 53, 6523–6526
10.
WuY, KitajimaM, KogureN, WangY, ZhangR, TakayamaH. (2010) Two new Aspidosperma indole alkaloids from Yunnan Kopsia arborea. Chemical & Pharmaceutical Bulletin, 58, 961–963
11.
WuY, KitajimaM, KogureN, WangY, ZhangR, TakayamaH. (2009) Kopsiyunnanines F and isocondylocarpines: New tubotaiwine-type alkaloids from Yunnan Kopsia arborea. Journal of Natural Medicines, 63, 283–289
12.
WuY, SuehiroM, KitajimaM, MatsuzakiT, HashimotoS, NagaokaM, ZhangR, TakayamaH. (2009) Rhazinilam and quebrachamine derivatives from Yunnan Kopsia arborea. Journal of Natural Products, 72, 204–209
13.
WuY, KitajimaM, KogureN, ZhangR, TakayamaH. (2008) Two novel indole alkaloids, kopsiyunnanines A and B, from a Yunnan Kopsia. Tetrahedron Letters, 49, 5935-5938 and 6596.
