A chemical investigation of Aspidosperma excelsum yielded excelsinidine (1), a quaternary indole alkaloid possessing an unusual 1-azoniatricyclo[4.3.3.0]undecane moiety, along with the known compound aspidodasycarpine (2). Structural elucidation was effected by a combination of 1D- and 2D-NMR spectroscopic techniques, along with mass spectral studies.
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2.
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3.
JouleJA, OhashiM, GilbertOB, DjerassiC. (1965) Alkaloid Studies- LIII. The Strucutures of Nine New Alkaloids from Aspidosperma dasycarpon A. DC. Tetrahedron, 21, 1717–1734.
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ItohA, KumashiroT, YamaguchiM, NagakuraN, MizushinaY. Nishi T, TanahashiT. (2005) Indole alkaloids and other constituents of Rauwolfia serpentia.Journal of Natural Products, 68, 848–852.
