Free accessResearch articleFirst published online 2014-8
Use of Circular Dichroism to Determine the Absolute Configuration of a Pimarane Diterpenoid from the Southern African Sclerocroton integerrimus (Euphorbiaceae)
From the stem bark and leaves of Sclerocroton integerrimus, eight compounds, including 17-hydroxy-ent-pimara-8(14),15-dien-3-one (1), were isolated. The structures of the compounds were determined on the basis of spectroscopic analysis. The absolute configuration of 17-hydroxy-ent-pimara-8(14),15-dien-3-one was confirmed from electronic circular dichroism studies.
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