Two new compounds, (E)-4-(3, 4-dihydroxyphenyl)-N-(1-hydroxy-2-(4-hydroxyphenyl) ethyl)-2-oxobut-3-enamide (1) and phloretin2-O-β-D-apiofuranosyl (1→6)-β-D-glucopyranoside (2) were isolated from Lithocarpus polystachyus Rehd. Their structures were determined on the basis of analysis of their 1D and 2D NMR spectroscopic and mass spectral data.
HouSZ, ChenSX, HuangS, JiangDX, ZhouCJ, ChenCQ, LiangYM, LaiXP. (2011) The hypoglycemic activity of Lithocarpus polystachyus Rehd. leaves in the experimental hyperglycemic rats. Journal of Ethnopharmacology, 138, 142–149
2.
HouSZ, XuSJ, JiangDX, ChenSX, WangLL, HuangS, LaiXP. (2012) Effect of the flavonoid fraction of Lithocarpus polystachyus Rehd. on spontaneously hypertensive and normotensive rats. Journal of Ethnopharmacology, 143, 441–447.
LiSH, WuXJ, YangQD, ChenYY, ZhouN. (2010) Studies on the chemical constituents of Lithocarpus polystachyus. Journal of Chinese Medicinal Materials, 33, 549–551
5.
LiSH, WuXJ, ZengJY, ZhangJ, ZhouN. (2010) Studies on the flavonoids of Lithocarpus polystachyus. Chinese Traditional and Herbal Drugs, 41, 1967–1969
6.
HeCN, PengY, XiaoW, YanY, HuYL, XiaoPG. (2012) Research progress of Lithocarpus polystachyus. Lishizhen Medicine and Materia Medica Research, 23, 1253–1255
7.
JinHX, ZhaoY, LaiXP, ChenJN, HuangS. (2012) Chemical constituents from Lithocarpus polystachyus Rehd. Chinese Traditional Patent Medicine, 34, 98–100.
8.
IkumiY, KidaT, SakumaS, YamashitaS, AkashiM. (2008) Polymer-phloridzin conjugates as an anti-diabetic drug that inhibits glucose absorption through the Na+/glucose cotransporter (SGLT1) in the small intestine. Journal of Controlled Release, 125, 42–49
9.
VessalM, HemmatiM, VaseiM. (2003) Antidiabetic effects of quercetin in streptozocin-induced diabetic rats. Comparative Biochemistry and Physiology Part C, 135, 357–364
10.
DongHQ, LiM, ZhuF, LiuFL, HuangJB. (2012) Inhibitory potential of trilobatin from Lithocarpus polystachyus Rehd against α-glucosidase and α-amylase linked to type 2 diabetes. Food Chemistry, 130, 261–266.
11.
HiltP, SchieberA, YildirimC, ArnoldG, KlaiberI, ConradJ, BeifussU, CarleR.(2003) Detection of phloridzin in strawberries (Fragaria x ananassa Duch.) by HPLC-PDA-MS/MS and NMR spectroscopy. Journal of Agricultural and Food Chemistry. 51, 2896–2899.