Two isoprenylated flavanones, macatrichocarpins A and B, and two isoprenylated dihydrochalcones, macatrichocarpins C and D, have been isolated and identified from the acetone extract of the leaves of Macaranga trichocarpa. The structures of these compounds were determined based on spectroscopic data, including UV, IR, 1D and 2D NMR spectroscopic and HREIMS data. This is the first report of the presence of dihydrochalcone derivatives in the genus Macaranga.
BlattnerFR, WeisingK, BanferG, MaschwitzU, FialaB. (2001) Molecular analysis of phylogenetic relationships among Myrmecophytic Macaranga species (Euphorbiaceae). Molecular Phylogenetics and Evolution, 19, 331–334.
2.
YoderBJ, CaoS, NorrisA, MillerJS, RatovosonF, RazafitsalamaJ, AndriantsiferanaR, RasamisonVE, KingstonDGI. (2007) Antiproliferative prenylated stilbenes and flavonoids from Macaranga alnifolia from the Madagascar rainforest. Journal of Natural Products, 70, 342–346.
3.
HakimEH, JuliawatyLD, SyahYM, AchmadSA. (2005) Molecular diversity of Artocarpus champeden (Moraceae): a species endemic to Indonesia. Molecular Diversity, 9, 149–158.
4.
HakimEH, AchmadSA, JuliawatyLD, MakmurL, SyahYM, AimiN, KitajimaM, HiromitsuH, GhisalbertiEL. (2006) Prenylated flavonoids and related compounds on the Indonesian Artocarpus (Moraceae). Journal of Natural Medicines, 60, 161–184.
5.
NkengfackAE, SansonDR, TempestaMS, Tanee FomumZ. (1989) Erythrina studies. Part 13. Two new flavonoids from Erythrina eriotriocha. Journal of Natural Products, 52, 320–324.
6.
MabryTJ, MarkhamKR, ThomasMB. (1970) The Systematic Identification of Flavonoids, Springer-Verlag, New York, pp. 165–226.
7.
PhommartS, SutthivaiyakitP, ChimnoiN, RuchirawatS, SutthivaiyakitS. (2005) Constituents of the leaves ofMacaranga tanarius. Journal of Natural Products, 68, 927–930.
8.
SultanaS, IlyasM. (1987) Chemical investigation of Macaranga indica Wight. Indian Journal of Chemistry, 26B, 801–802.
TsengM-H, ChouC-H, ChenY-M, KuoY-H. (2001) Allelopathic prenylflavanones from the fallen leaves ofMacaranga tanarius. Journal of Natural Products, 64, 827–828.
11.
DinhV, ZhangH-P, DucNM, TuuNV, QinG-W. (2006) A new geranylated flavanone from Macaranga triloba. Journal of Asian Natural Products Research, 8, 155–158.
12.
SutthivaiyakitS, UnganontS, SutthivaiyakitP, SuksamranA. (2002) Diprenylated and prenylated flavonoids from Macaranga denticulata. Tetrahedron, 58, 3619–3622.
13.
JangDS, CuendetM, HawthorneME, KardonoLBS, KawanishiK, FongHHS, MehtaRG, PezzutoJM, KinghornAD. (2002) Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2. Phytochemistry, 61, 867–872.
14.
HnawiaE, ThoisonO, Gueritte-VoegeleinF, BourretD, SevenetT. (1990) A geranyl substituted flavonol from Macaranga vedeliana. Phytochemistry, 29, 2367–2368.
15.
SultanaS, IlyasM. (1986) Chromenoflavones from Macaranga indica. Phytochemistry, 25, 953–954.
16.
JangDS, CuendetM, PawlusAD, KardonoLBS, KawanishiK, FarnsworthNR, FongHHS, PezzutoJM, KinghornAD. (2004) Potential cancer chemopreventive constituents of the leaves ofMacaranga triloba. Phytochemistry, 65, 345–350.
17.
ThoisonO, HnawiaE, Gueritte-VoegeleinF, SevenetT. (1992) Vedelianin, a hexahydroxanthene derivative isolated from Macaranga vedeliana. Phytochemistry, 31, 1439–1442.
18.
BeutlerJA, ShoemakerRH, JohnsonT, BoydMR. (1998) Cytotoxic geranyl stilbenes from Macaranga scweinfurthii, Journal of Natural Products, 61, 1509–1512.
19.
van der KaadenJE, HemscheidtTK, MooberrySL. (2001) Mappain, a new cytotoxic prenylated stilbene from Macaranga mappa, Journal of Natural Products, 64, 103–105.
20.
MaM, ShangX, WangS, LiS, YangY, ShiJ. (2007) Chemical constituents from branch of Macaranga adenantha and their TNF-α inhibitory activity. Zhongguo Zhongyao Zazhi, 32, 1175–1179.
