The new oxepin-containing (1) and quinazolinone (2) alkaloids and new dihydrobenzofuran derivative (3) have been isolated from a marine strain of Aspergillus carneus KMM 4638. The structures of these metabolites were determined by HR-MS and 1D and 2D NMR, along with Marfey's method.
Leandrini de OliveiraA.L., de FelícioR., DebonsiH.M. (2012) Marine natural products: chemical and biological potential of seaweeds and their endophytic fungi. Revista Brasileira de Farmacognosia Brazilian Journal of Pharmacognosy, 22, 906–920.
2.
RatebM.E., EbelR. (2011) Secondary metabolites of fungi from marine habitats. Natural Product Report, 28, 290–344.
3.
DebbabA., AlyA.H., LinW.H., ProkschP. (2010) Bioactive compounds from marine bacteria and fungi. Microbial Biotechnology, 3, 544–563.
4.
DebbabA., AlyA.H., LinW.H., ProkschP. (2012) Endophytes and associated marine derived fungi—ecological and chemical perspectives. Fungal Diversity, 57, 45–83.
5.
AfiyatullovS.S., KuznetsovaT.A., IsakovV.V., PivkinM.V., Prokof'evaN.G., ElyakovG.B. (2000) New diterpene altrosides of the fungus Acremonium striatisporum isolated from a sea cucumber. Journal of Natural Products, 63, 848–850.
6.
SprogøeK., MannicheS., LarsenT.O., ChristophersenC. (2005) Janoxepin and brevicompanine B: antiplasmodial metabolites from the fungus Aspergillus janus. Tetrahedron, 61, 8718–8721.
7.
FujiiK., ShimoyaT., IkaiY., OkaH., HaradaK. (1998) Further application of advanced Marfey's method for determination of absolute configuration of primary amino compound. Tetrahedron Letters, 39, 2579–2582.
8.
CutlerH.G., SpringerJ.P., ArrendaleR.F., ArisonB.H., ColeP.D., RobertsR.G. (1988) Cinereain: a novel metabolite with plant regulating properties from Botrytis cinerea. Agricultural and Biological Chemistry, 52, 1725–1733.
9.
BelofskyG.N., AngueraM., JensenP.R., FenicalW., KöckM. (2000) Oxepinamides A-C and fumiquinazolines H-I: bioactive metabolites from a marine isolate of a fungus of the genus Acremonium. Chemistry a European Journal, 6, 1355–1360.
10.
LiX.H., ShiQ.W., ZhengZ.H., KeA.B., ZhangH., HuoC.H., MaY., RenX., LiY.Y., LinJ., JiangQ., GuY.C., KiyotaH. (2011) Oxepinamides: novel liver X receptor agonists from Aspergillus peniceus. European Journal of Organic Chemistry, 4, 802–807.
11.
LiG.Y., YangT., LuoY.G., ChenX.Z., FangD.M., ZhangG.L. (2009) Brevianamide J, a new indole alkaloid dimmer from fungus Aspergillus versicolor. Organic Letters, 11, 3714–3717.
12.
LiG.Y., LiL.M., YangT., ChenX.Z., FangD.M., ZhangG.L. (2010) Four new alkaloids, brevianamides O-R, from the fungus Aspergillus versicolor. Helvetica Chimica Acta, 93, 2075–2080.
13.
LeeS.U., AsamiY., LeeD., JangJ.H., AhnJ.S., OhH. (2011) Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044. Journal of Natural Products, 74, 1284–1287.
14.
ZhuravlevaO.I., AfiyatullovS.S., DenisenkoV.A., ErmakovaS.P., SlinkinaN.N., DmitrenokP.S., KimN.Y. (2012) Secondary metabolites from a marine-derived fungus Aspergillus carneus Blochwitz. Phytochemistry, 80, 123–131.
15.
Martin-SantamariaS., BuenadichaF.L., EspadaM., SöllhuberM., AvendañoC. (1997) Regio- and diastereoselective alkylation of 2-substituted 2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones. Journal of Organic Chemistry, 62, 6424–6428.
16.
WangH., SimM.M. (2001) Total solid phase syntheses of the quinazoline alkaloids: verrucines A and B and anacine. Journal of Natural Products, 64, 1497–1501.
17.
JangJ.H., KanohK., AdachiK., ShizuriY. (2006) New dihydrobenzofuran derivative, awajanoran, from marine-derived Acremonium sp. AWA16–1. The Journal of Antibiotics, 59, 428–431.
18.
ShaoC., SheZ., GuoZ., PengH., CaiX., ZhouS., GuY., LinY. (2007) H–1 and C–13 NMR assignments for two anthraquinones and two xanthones from the mangrove fungus (ZSUH-36). Magnetic Resonance in Chemistry, 45, 434–438.
19.
CarmichaelJ., DegraffW.G., GazdarA.F., MinnaJ.D., MitchellJ.B. (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay – assessment of chemosensitivity testing. Cancer Research, 47, 936–942.