A New Sulfated Triterpene Saponin from Gypsophila trichotoma

Abstract

A new sulfated triterpeniod saponin, 3-O-sulfooleanolic acid 28-O-[β-glucopyranosyl-(1→3)]-[β-glucopyranosyl-(1→6)]-β-glucopyranosyl ester (1), along with three known Δ⁷-sterols: stigmast-7-en-3β-ol (2), stigmast-7-en-3-O-β-D-glucopyranoside (3) and stigmast-7-en-3-on (4) were isolated from the roots of Gypsophila trichotoma Wend. (Caryophyllaceae). Their structures were elucidated by chemical and spectral methods. Compound 1 caused concentration-dependent inhibition of malignant cell proliferation against different human tumor cell lines.

Keywords

Gypsophila trichotoma Sulfated saponin

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