A total of 16 phenolic compounds, including one new and five known N-cinnamoyl phenylethylamides, one new pyrrole alkaloid named portulacaldehyde, five phenylpropanoid acids and amides, and derivatives of benzaldehyde and benzoic acid, were isolated and identified from a polar fraction of an extract of Portulaca oleracea. Their structures were determined through spectroscopic analyses.
ChanK., IslamM.W., KamilM., RadhakrishnanR., ZakariaM.N.M., HabibullahM., AttasA. (2000) The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. sativa (Haw.) Celak. Journal of Ethnopharmacology, 73, 445–451.
2.
RashedA.N., AfifiF.U., DisiA.M. (2003) Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1. Journal of Ethnopharmacology, 88, 131–136.
3.
OkuyamaT., ShibataS., HosonM., KawadaT., OsadaH., NoguchiT. (1986) Effect of Oriental plant drugs on platelet aggregation; III. Effect of Chines [sic] drug “Xiebai” on human platelet aggregation. Planta Medica, 52, 171–175.
4.
MizutaniM., HashidokoY., TaharaS. (1998) Factors responsible for inhibiting the motility of zoospores of the phytopathogenic fungus Aphanomyces cochlioides isolated from the non-host plant Portulaca oleracea. FEBS Letters, 438, 236–240.
5.
DownieI.M., EarleM.J., HeaneyH., ShuhaibarK.F. (1993) Vilsmeier formylation and glyoxylation reactions of nucleophilic aromatic compounds using pyrophosphoryl chloride. Tetrahedron, 49, 4015–4034.
6.
PouchertC.J., BehnkeJ. (1993) The Aldrich library of 13C and 1H FT NMR spectra.Aldrich Chemical Company, Wisconsin.
7.
KapadiaG.J., HighetR.J. (1968) Peyote alkaloids IV. Structure of peyonine, novel β-phenethylpyrrole from Lophophora williamsii. Journal of Pharmaceutical Sciences, 57, 191–192.
8.
KapadiaG.J., FayezM.B.E. (1973) The chemistry of peyote alkaloids. Lloydia, 36, 9–35.
9.
PabuççuoğluV., ArarG., GözlerT., FreyerA.J., ShammaM. (1989) Nitrotyrasanguinarine: an unusual nitrated benzophenanthridine alkaloid from Hypecoum species. Journal of Natural Products, 52, 716–719.
10.
SariA. (2001) The constituents of the aerial parts of Glaucium grandiflorum var. grandiflorum. Acta Pharmaceutica Turcica, 43, 89–92.
11.
SariA., SariyarG. (1997) Isolation of triniifoline, miltanthaline and some medicinally important alkaloids from Papaver triniifolium. Planta Medica, 63, 575–576.
12.
WuY.C., ChangG.Y., KoF.N., TengC.M. (1995) Bioactive constituents from the stems of Annona montana. Planta Medica, 61, 146–149.
13.
CutilloF., C'AbroscaB., DellaGrecaM., Di MarinoC., GolinoA., PreviteraL., ZarrelliA. (2003) Cinnamic acid amides from Chenopodium album: effects on seeds germination and plant growth. Phytochemistry, 64, 1381–1387.
14.
TsengC.F., IwakamiS., MikajiriA., ShibuyaM., HanaokaF., EbizukaY., PadmawinataK., SankawaU. (1992) Inhibition of in vitro prostaglandin and leukotriene biosyntheses by cinnamoyl-β-phenethylamine and N-acyldopamine derivatives. Chemical and Pharmaceutical Bulletin, 40, 396–400.
15.
ParkJ.B. (2007) Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-selectin. Journal of Agricultural and Food Chemistry, 55, 2171–2175.
16.
LimE.J., KangH.J., JungH.J., KimK., LimC.J., ParkE.H. (2008) Anti-inflammatory, anti-antiogenic and anti-nociceptive activities of 4-hydroxybenzaldehyde. Biomolecules & Therapeutics, 16, 231–236.
17.
HsiehY.H., KuoP.M., ChienS.C., ShyurL.F., WangS.Y. (2007) Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide. Phytomedicine, 14, 675–680.
18.
JungH.J., SongY.S., LimC.J., ParkE.H. (2009) Evaluation on pharmacological activities of 2,4-dihydroxybenzaldehyde. Biomolecules & Therapeutics, 17, 263–269.