Two samples of Ligularia kanaitzensis collected in the Shizhongshan Mountain region of Yunnan Province, as well as one sample collected in Sichuan Province, were analyzed with regard to root constituents and neutral DNA sequences. The two Shizhongshan samples were found to be different from each other and from other samples analyzed previously, indicating that the intra-specific diversity in the species was highly complex.
LiuSW, DengDS, LiuJQ. (1994) The origin, evolution and distribution of Ligularia Cass. (Compositae). Acta Phytotaxonomica Sinica, 32, 514–524.
4.
ToriM, OkamotoY, TachikawaK, MiharaK, WatanabeA, SakaokuM, TakaokaS, TanakaM, GongX, KurodaC, HattoriM, HanaiR. (2008) Isolation of new eremophilane-type sesquiterpenoids, subspicatins A-D and subspicatolide from Ligularia subspicata, and chemical and genetic diversity of the species. Tetrahedron, 64, 9136–9142;
5.
NaganoH, TorihataA, MatsushimaM, HanaiR, SaitoY, BabaM, TanioY, OkamotoY, TakashimaY, IchiharaM, GongX, KurodaC, ToriM. (2009) Chemical and genetic study of Ligularia cyathiceps in Yunnan Province of China. Helvetica Chimica Acta, 92, 2071–2081;
6.
TorihataA, ChaoX, KurodaC, HanaiR, HirotaH, GongX. (2009) Chemical and genetic differentiation of Ligularia hodgsonii in Japan and China. Chemistry and Biodiversity, 6, 2184–2191;
7.
NaganoH, KandaM, YamadaH, HanaiR, GongX, KurodaC. (2010) Chemical and genetic study of Ligularia anoleuca and L. veitchiana in Yunnan and Sichuan Provinces of China. Helvetica Chimica Acta, 93, 1945–1952;
8.
NaganoH, MatsushimaM, YamadaH, HanaiR, GongX, KurodaC. (2010) Two new furanoeremophilane sesquiterpenoids from Ligularia oligonema. Natural Product Communications, 5, 1–4.
9.
SaitoY, HattoriM, IwamotoY, TakashimaY, MiharaK, SasakiY, FujiwaraM, SakaokuM, ShimizuA, ChaoX, KurodaC, GongX, HanaiR, ToriM. (2011) Overlapping chemical and genetic diversity in Ligularia lamarum and Ligularia subspicata. Isolation of ten new eremophilanes and a new seco-bakkane compound. Tetrahedron, 67, 2220–2231.
10.
HanaiR, GongX, ToriM, KondoS, OtoseK, OkamotoY, NishihamaT, MuritaA, ShenY, WuS, KurodaC. (2005) Chemical and genetic study of Ligularia tongolensis, Ligularia cymbulifera, and Ligularia atroviolacea in the Hengduan Mountains of China. Bulletin of the Chemical Society of Japan, 78, 1302–1308.
11.
NaganoH, IwazakiY, MatsushimaM, SatoM, GongX, ShenY, HirotaH, KurodaC, HanaiR. (2007) High diversity of Ligularia dictyoneura in chemical composition and DNA sequence. Chemistry and Biodiversity, 4, 2874–2888.
12.
KurodaC, HanaiR, NaganoH, ToriM, GongX. (2012) Diversity of furanoeremophilanes in major Ligularia species in the Hengduan Mountains. Natural Product Communications, 7, 539–548.
13.
ToriM, WatanabeA, MatsuoS, OkamotoY, TachikawaK, TakaokaS, GongX, KurodaC, HanaiR. (2008) Diversity of Ligularia kanaitzensis in sesquiterpenoid composition and neutral DNA sequences. Tetrahedron, 64, 4486–4495.
14.
KurodaC, UeshinoT, NaganoH. (2004) Ehrlich's reaction of furanoeremophilanes. Bulletin of the Chemical Society of Japan, 77, 1737–1740.
15.
KurodaC, NishioE. (2007) Substituent effect in color of Ehrlich's test of tetrahydrobenzofuran. Natural Product Communications, 2, 581–585.
JenningsPW, ReederSK, HurleyJC, CaughlanCN, SmithGD. (1974) Isolation and structure determination of one of the toxic constituents from Tetradymia glabrata. The Journal of Organic Chemistry, 39, 3392–3398.
18.
BohlmannF, ZderoC. (1974) Über neue sesquiterpene der gattung Senecio. Chemische Berichte, 109, 2912–2922.
19.
NayaK, YoshimuraF, TakagiI. (1971) The structure of petasitolone, a new constituent of Petasites japonicus Maxim. Bulletin of the Chemical Society of Japan, 44, 3165–3167;
20.
LiuHS, KgooiTK. (1984) Total synthesis of (±)-petasitelone. Canadian Journal of Chemistry, 62, 2676–2681.
21.
ShibuyaH, TakedaY, ZhangR, TongRX, KitagawaI. (1992) Indonesian medicinal plants III. On the constituents of the bark of Fagara rhetza (Rutaceae). (1): Alkaloids, phenylpropanoids, and acid amide. Chemical and Pharmaceutical Bulletin, 40, 2325–2330.
22.
LiY, WangZ, ZhangM, LuoS, ChenJ. (2002) Study on the terpene compounds from Ligularia kanaitzensis. Journal of Chinese Pharmaceutical Sciences, 11, 115–117.
23.
IidaK, MitaniM, KurodaC. (2007) Fixation of natural furanoeremophilane by Diels-Alder reaction. Bulletin of the Chemical Society of Japan, 80, 966–971.
24.
TamuraK, PetersonD, PetersonN, StecherG, NeiM, KumarS (2011) MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Molecular Biology and Evolution, 28, 2731–2739.
