The essential oils from leaves and stem barks of Drimys brasiliensis Miers (Winteraceae), collected in July and December 2008, were analyzed by GC/FID and GC/MS. The stem bark oils were composed mainly of monoterpenes (July, 45±3%; December, 92±4%), while the oils from leaves showed the predominance of sesquiterpenes (July, 47±1%; December, 55±1%). The variation in the relative amount of constituents could be associated, at least in part, to several microclimatic parameters such as precipitation, temperature and/or phenological state, which were different for each collection of D. brasiliensis.
CunhaFM, FrödeTS, MendesGL, MalheirosA, CechinelFo. V, YunesRA, CalixtoJB. (2001) Additional evidence for the anti-inflammatory and anti-allergic proprieties of the sesquiterpene polygodial. Life Sciences, 70, 159-169.
4.
KuboI, TanigushiM. (1988) Polygodial, an antifungal potentiator. Journal of Natural Products, 51, 22-29.
5.
KuboI, FujitaK-I, LeeSH. (2001) Antifungal mechanism of polygodial. Journal of Agriculture and Food Chemistry, 49, 1607-1611.
6.
MalheirosA, CechinelFO. V., SchimittCB, YunesRA, ExcalanteA, SvetazL, ZacchinoS, MonacheFD. (2005) Antifungal activity of drimane sesquiterpenes from Drimys brasiliensis using bioactivity-guided fractionation. Journal of Pharmacy and Pharmaceutical Science, 8, 335-339.
7.
MalheirosA, CechinelFV, SchimittCB, SantosArs, ScheidtC, CalixtoJB, MonacheFD, YunesRA (2001) A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark. Phytochemistry, 57, 103-107.
8.
CechinelFV, SchlemperV, SantosArs, PinheiroTR, YunesRA, MendesGL, CalixtoJB, MonacheFD. (1998) Isolation and identification of active compounds from Drimys winteri barks. Journal of Ethnopharmacology, 62, 223-227.
9.
AndreE, FerreiraJ, MalheirosA, YunesRA, CalixtoJB. (2004) Evidence for the involvement of vanilloid receptor in the antinocipeption produced by dialdeydes unsaturated sesquiterpenes polygodial and drimanial in rats. Neuropharmacology, 46, 590-597.
10.
MendesGL, SantosArs, CamposMM, TratskKS, YunesRA, CechinelFV, CalixtoJB. (1998) Anti-hyperanalgesic proprieties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drimys winteri (Winteraceae). Life Sciences, 63, 369-381.
11.
McCallionRF, ColeAlj, WalkerJrl, BluntJW, MunroMhg. (1982) Antibiotic substances from New Zealand plants II. Polygodial, an anti-candida agent from Pseudowintera colorata. Journal of Medicinal Plant Research, 44, 134-138.
12.
LimbergerRP, ScopelM, SobralM, HenriquesAT. (2007) Comparative analysis of volatiles from Drimys brasiliensis Miers and D. angustifolia Miers (Winteraceae) from southern Brazil. Biochemical Systematics and Ecology, 35, 130-137.
Gobbo-NetoL, LopesNP. (2007) Plantas medicinais: fatores de influência no conteúdo de metabólitos secundários. Quimica Nova, 30, 374-381.
18.
LagoJhg, FaveroOA, RomoffP. (2006) Microclimatic factors and phenology influences in the chemical composition of the essential oils from Pittosporum undulatum Vent. leaves. Journal of the Brazilian Chemical Society, 17, 1334-1338.
19.
VallatA, GuHN, DornS (2005) How rainfall, relative humidity and temperature influence volatile emissions from apple trees in situ. Phytochemistry, 66, 1540-1550.
