A new tricyclic clerodane-type diterpenoid, trivially named phlomeoic acid (1), was isolated from the methanolic extract of Phlomis bracteosa, together with two known compounds, ursolic acid and glutinol, isolated for the first time from this species. Their structures were elucidated by means of spectroscopic and mass spectrometric techniques and comparison with literature data.
AlbaladejoRG, AparicioA, SilvestreS. (2004) Variation patterns in the Phlomis x composita (Lamiaceae) hybrid complex in the Iberian Peninsula. Botanical Journalof the Linnean Society, 145, 97-108.
2.
KyriakopoulouI, MagiatisP, SkaltsounisA-L, AligiannisN, HarvalaC. (2001) Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia. Journal of Natural Products, 64, 1095-1097.
3.
CalisI, KırmızıbekmezH. (2004) Glycosides from Phlomis lunariifolia. Phytochemistry, 65, 2619-2625.
4.
SarkhailP, Monsef-EsfehaniHR, AminG, SurmaghiMhs, ShafieeA. (2006) Phytochemical study of Phlomis olivieri Benth. and Phlomis persica Boiss. DARU, 14, 115-121.
5.
KamelMS, MohamedKM, HassaneanHA, OhtaniK, KasaiR, YamasakiK. (2000) Iridoid and megastigmane glycosides from Phlomis aurea. Phytochemistry, 55, 353-357.
AhmadVU, KhanA, FarooqU, KousarF, KhanSS, HussainJ. (2007) Two new trans-clerodane diterpenoids from Otostegia limbata. Journal of Asian Natural Products Research, 9, 91-95.
8.
ManabeS, NishinoC. (1986) Stereochemistry of cis-clerodane diterpenes. Tetrahedron, 42, 3461-3470.
9.
KubracMN, PopaDP. (1980) The essential oils lactones of Nepeta transcaucasica and Nepeta sibirica. Khimiya Prirodnykh Soedinenii, 3, 420-421.
10.
HeymannH, TezukaY, KikuchiT, SupriyatnaS. (1994) Constituents of Sindora sumatrana MIQ. III. New trans-clerodane diterpenoids from the dried pods. Chemical and Pharmaceutical Bulletin, 42, 1202-1207.
11.
BarretoAds, CarvalhoMgd, NeryIda, GonzagaL, KaplanMac. (1998), Chemical constituents from Himatanthus articulata.Journal of Brazilian Chemical Society, 9, 430-434.
