The essential oil from the aerial parts of Artemisia scoparia was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. A total of 32 compounds were identified representing 98.0% of the total oil composition. A. scoparia oil was dominated by the diacetylenes 1-phenyl-2,4-pentadiyne (34.2%) and capillene (4.9%). Other major components were β-pinene (21.3%), methyl eugenol (5.5%), α-pinene (5.4%), myrcene (5.2%), limonene (5.0%), and (E)-β-ocimene (3.8%). The oil was tested for in-vitro cytotoxic activity against MCF-7 cells, but was inactive.
HayatMQ, KhanMA, AshrafM, JabeenS. (2009) Ethnobotany of the genus Artemisia L. (Asteraceae) in Pakistan. Ethnobotany Research and Applications, 7147-162;
2.
TanRX, ZhengWF, TangHQ. (1998) Biologically active substances from the genus Artemisia. Planta Medica, 64295-302;
3.
Lopes-LutzD, AlvianoDS, AlvianoCS, KolodziejczykPP. (2008) Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry, 691732-1738;
4.
NibretE, WinkM. (2010) Volatile components of four Ethiopian Artemisia species extracts and their in vitro antitrypanosomal and cytotoxic activities. Phytomedicine, 17, 369-374.
5.
RamezaniM, Fazli-BazzazBS, Saghafi-KhademF, DabaghianA. (2004) Antimicrobial activity of four Artemisia species of Iran. Fitoterapia, 75201-203;
6.
RanaCS, SharmaA, KumarN, DangwalLR, TiwariJK. (2010). Ethnopharmacology of some important medicinal plants of Nanda Devi National Park (NDNP) Uttarakhand, India. Nature and Science, 89-14;
7.
HamayunM, AfzalS, KhanMA. (2006) Ethnopharmacology, indigenous collection and preservation techniques of some frequently used medicinal plants of Utror and Gabral, district Swat, Pakistan. African Journal of Traditional, Complementary and Alternative Medicines, 3, 57-73.
8.
GolimovBP, AfanasievNM. (1957) Chemical composition of essential oil of Artemisia scoparia. Journal of General Chemistry, 27, 1698-1703.
9.
GoryaevMI, SharipovaFS, El'chibekovaLA, AverinaVY. (1981) Essential oil of Artemisia scoparia. Chemistry of Natural Compounds, 17, 400-403.
10.
KonovalovDA, KonovalovaOA, Chelombit'koVA. (1992) Chemical composition of the essential oil of Artemisia scoparia. Chemistry of Natural Compounds, 28, 121-122.
11.
BasherKhc, OzekT, DemirchakmakB, NuriddinovKR, AbduganievBY, AripovKN, KhodzimatovKK, NigmatullaevOA, ShamyanovED. (1997) Essential oils of some Artemisia species from Central Asia. Chemistry of Natural Compounds, 33293-295;
12.
KimJH. (1997) Variation of monoterpenoids in Artemisia feddei and Artemisia scoparia. Journal of Plant Biology, 40267-274;
13.
FarzanehM, AhmadzadehM, HadianJ, TehraniAS. (2006) Chemical composition and antifungal activity of the essential oils of three species of Artemisia on some soil-borne phytopathogens. Communications in Agricultural and Applied Biological Sciences, 711327-1333;
14.
KhayyatMH, KarimiH. (2004) Composition of the volatile oils of three different species of Artemisia. Iranian Journal of Pharmaceutical Sciences, 133-37;
15.
KapoorR, AliM, MirSR, RafiullahRM. (2004) Essential oil constituents of aerial parts of Artemisia scoparia Waldst. & Kit. Flavour and Fragrance Journal, 19109-111;
16.
ChaJD, JeongMR, JeongSI, MoonSE, KimJY, KilBS, SongYH. (2005) Chemical composition and antimicrobial activity of the essential oils of Artemisia scoparia and A. capillaries. Planta Medica, 71186-190;
17.
Morteza-SemnaniK, AkbarzadehM. (2005) Essential oils composition of Iranian Artemisia absinthium L. and Artemisia scoparia Waldst. et Kit. Journal of Essential Oil Research, 17321-322;
18.
DemirciB, DemirciF, BaşerKhc. (2005)Headspace-SPME and hydrodistillation of two fragrant Artemisia sp. Flavour and Fragrance Journal, 10, 395-398.
19.
Safaei-GhomiJ, BamoniriA, SarafrazMB, BatooliH. (2005) Volatile components from Artemisia scoparia Waldst et Kit growing in central Iran. Flavour and Fragrance Journal, 20650-652;
20.
NegahbanM, MoharramipourS, SefidkonF. (2006) Chemical composition and insecticidal activity of Artemisia scoparia essential oil against three coleopteran stored-product insects. Journal of Asia-Pacific Entomology, 91-8;
21.
MirjaliliMH, TabatabaeiSmf, HadianJ, EbrahimiSN, SonboliA. (2007) Phenological variation of the essential oil of Artemisia scoparia Waldst. et Kit from Iran. Journal of Essential Oil Research, 19326-329;
22.
SinghHP, KaurS, MittalS, BatishDR, KohliRK. (2008) Phytotoxicity of major components of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit. Zeitschrift für Naturforschung, 63c, 663-666;
23.
SinghHP, KaurS, MittalS, BatishDR, KohliRK. (2009) Essential oil of Artemisia scoparia inhibits plant growth by generating reactive oxygen species and causing oxidative damage. Journal of Chemical Ecology, 35154-162;
24.
SinghHP, MittalS, KaurS, BatishDR, KohliRK. (2009) Chemical composition and antioxidant activity of essential oil from residues of Artemisia scoparia. Food Chemistry, 114642-645;
25.
KaurS, SinghHP, MittalS, BatishDR, KohliRK. (2010) Phytotoxic effects of volatile oil from Artemisia scoparia against weeds and its possible use as a bioherbicide. Industrial Crops and Products, 32, 54-61;
26.
SinghHP, KaurS, MittalS, BatishDR, KohliRK. (2010) In vitro screening of essential oil from young and mature leaves of Artemisia scoparia compared to its major constituents for free radical scavenging activity. Food and Chemical Toxicology, 48, 1040-1044.
27.
FerreiraZS, GottliebOR. (1982) Polyacetylenes as systematic markers in dicotyledons. Biochemical Systematics and Ecology, 10155-160;
28.
StevensKL, WittSC, TurnerCE. (1990) Polyacetylenes in related thistles of the subtribes Centaureinae and Carduinae. Biochemical Systematics and Ecology, 18229-232;
29.
ChristensenLP, LamJ. (1990) Acetylenes and related compounds in Cynareae. Phytochemistry, 29, 2753-2785.
30.
WallnöferB, HoferO, GregerH. (1989)Polyacetylenes from the Artemisia ‘Vulgares’ group. Phytochemistry, 28, 2687-2691.
31.
JuteauF, MasottiV, BessièreJM, VianoJ. (2002)Compositional characteristics of the essential oil of Artemisia campestris var. glutinosa. Biochemical Systematics and Ecology, 30, 1065-1070.
32.
MiyazawaM, KameokaH. (1977) The essential oil of Artemisia capillaris. Phytochemistry, 161054-1057;
ChauhanRS, KitchluS, RamG, KaulMK, TavaA. (2010)Chemical composition of capillene chemotype of Artemisia dracunculus L. from North-West Himalaya, India. Industrial Crops and Products, 31, 546-549.
36.
YashinaOG, VereshchaginLI. (1978) Natural and synthetic acetylenic antimycotics. Russian Chemical Reviews, 47307-317;
37.
ArnasonT, SwainT, WatCK, GrahamEA, PartingtonS, TowersGhn, LamJ. (1981) Mosquito larvicidal activity of polyacetylenes from species in the Asteraceae. Biochemical Systematics and Ecology, 963-68;
38.
SalehMA. (1984) An insecticidal diacetylene from Artemisia monosperma. Phytochemistry, 232497-2498;
39.
McLachlanD, ArnasonT, LamJ. (1986) Structure-function relationships in the phototoxicity of acetylenes from the Asteraceae. Biochemical Systematics and Ecology, 14, 17-23.
40.
SetzerWN, GuX, WellsEB, SetzerMC, MoriarityDM. (2000) Synthesis and cytotoxic activity of a series of diacetylenic compounds related to falcarindiol. Chemical and Pharmaceutical Bulletin, 481776-1777;
41.
DembitskyVM. (2006) Anticancer activity if natural and synthetic acetylenic lipids. Lipids, 41883-924;
RichmondJD, AgiusBR, WrightBS, HaberWA, MoriarityDM, SetzerWN. (2009) Essential oil compositions and cytotoxic activities of Dendropanax capillaris, Oreopanax nubigenus, and Schefflera rodrigueziana from Monteverde, Costa Rica. Natural Product Communications, 4, 271-274.
44.
AdamsRP. (2007) Identification of Essential Oil Components by Gas Chromatography / Mass Spectrometry, 4th Ed. Allured Publishing Co. Carol Stream, Illinois.