The toluene extract of the stem bark of N. purpurascens (R&P) Mez. contained a large amount of these 2-arylbenzofurans including methyl 7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran-5-carboxylate (2), a new benzofuran, along with three known compounds identified as kumatakenin (1), 5-(2-propenyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (3), and egonoic acid (4). The structure of the new compound was established on the basis of spectroscopic analysis.
WardRS. (1999) Lignans, neolignans and related compounds. Natural Product Reports, 19, 75–96;
2.
MendonçaPauletti P, AraújoAR, YoungMCM, GiesbrechtAM, Da SilvaBolzani V. (2000) nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity. Phytochemistry, 55, 597–601;
3.
ChérigoL, PolancoV, Ortega-BarriaE, HellerMV, CapsonTL, RiosLC. (2005) Antitrypanosomal activity of a novel norlignan purified from Nectandra lineata. Natural Product Research, 19, 373–377;
4.
KatsanouES, HalabalakiM, AligiannisN, MitakouS, SkaltsounisAL, AlexiX, PratsinisH, AlexisMN. (2007) Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: Modulation by adrenal and gonadal steroids. The Journal of Steroid Biochemistry and Molecular Biology, 104, 228–236;
5.
HanSJ, RyuSN, KangSS. (2004) A new 2-arylbenzofuran with antioxidant activity from the black colored rice (Oryza sativa). Chemical & Pharmaceutical Bulletin, 52, 1365–1366.
6.
ÖztürkSE, AkgülY, AnilH. (2008) Synthesis and antibacterial activity of egonol derivatives. Bioorganic & Medicinal Chemistry, 16, 4431–4437;
7.
KaoCL, ChernJW. (2002) A novel strategy for the synthesis of benzofuran skeleton neolignans: Application to ailanthoidol, XH-14, and obovaten. Journal of Organic Chemistry, 67, 6772–6787;
8.
ZhangJ, ZhangY, ZhangY, HerndonJW. (2003) Synthesis of benzofurans through coupling of dienylacetylenes with carbene complexes: total synthesis of egonol. Tetrahedron, 59, 5609–5616;
9.
MiyataO, TakedaN, NaitoT. (2004) Highly effective synthetic methods for substituted 2-arylbenzofurans using [3,3]-sgmatropic rearrangement: Short syntheses of stemofuran A and eupomatenoid 6. Organic Letters, 6, 1761–1763;
10.
DuanXF, ZengJ, ZhangZB, ZiGF. (2007) A facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings. Journal of Organic Chemistry, 72, 10283–10286.
11.
CroatTB. (1978) Flora of Barro Colorado Island, Stanford University Press, Stanford, California, USA, 410.
12.
GottliebOR. (1972) Chemosystematics of the Lauraceae. Phytochemistry, 11, 1537–1570;
13.
Da SilvaFilho AA, AlbuquerqueS, SilvaMLA, EberlinMN, TomazelaDM, BastosJK. (2004) Tetrahydrofuran lignans from Nectandra megapotamica with trypanocidal activity. Journal of Natural Products, 67, 42–45;
14.
Le QuesnePW, LarrahondoJE, RaffaufRF. (1980) Antitumor plants. X. Constituents of Nectandra rigida. Journal of Natural Products, 43, 353–359;
15.
GarcezFR, GarcezWS, MartinsM, CruzAC. (1999) A bioactive lactone from Nectandra gardneri. Planta Medica65, 775;
CiccióJF, ChaverriC, DíazC. (2009) Volatile compounds of Nectandra salicina (lauraceae) from Costa Rica and their cytotoxic activity on cell lines. Química Nova, 32, 417–420;
18.
CoyBarrera ED, CucaSuárez LE. (2009) Three new 7.3′,8.5′-connected bicyclo[3.2.1]octanoids and other neolignans from leaves of Nectandra amazonum NEES. (Lauraceae). Chemical & Pharmaceutical Bulletin, 57, 639–642;
19.
RibeiroAB, BolzaniVDS, YoshidaM, SantosLS, EberlindMN, SilvaDHS. (2005) A new neolignan and antioxidant phenols from Nectandra grandiflora. Journal of the Brazilian Chemical Society, 16, 526–530;
LuoY, HeZ, LiH. (2007) 2-Aryl benzofurans and their derivatives from seeds of Styrax macranthus. Fitoterapia, 78, 211–214.
24.
AkgulYY, AnilH. (2003) Benzofurans and another constituent from seeds of Styrax officinalis. Phytochemistry, 63, 939–943.
25.
LeeHJ, ParkSY, LeeOK, JoHJ, KangHY, ChoiDH, PaikKH, KhanM. (2008) Benzofurans and sterol from the seeds of Styrax obassia. Chemistry of Natural Compounds, 44, 435–439.