A new 2-arylbenzofuran derivative (diptoindonesin G) (1), along with nine known oligostilbenes, have been isolated and identified from the acetone extract of the tree bark of Hopea mengarawan. The structures of these compounds were determined based on spectroscopic data, including 2D NMR and HREIMS spectra. On cytotoxic evaluation of the isolated compounds against murin leukemia P-388 cells, compound 1 was the strongest in inhibiting the growth of the cells.
SotheeswaranS, PasupathyV. (1993) Distribution of resveratrol oligomers in plants. Phytochemistry, 32, 1083–1092.
2.
SeoE-K, DouglasKA. (2000) Bioactive constituents of the family Dipterocarpaceae. In: Atta-ur-Rahman (Ed.), Studies in Natural Products Chemistry, 23 (Bioactive Natural Products (Part D)), Elsevier, pp. 531–561.
3.
CichewiczRH, KouziSA. (2002) Resveratrol oligomers: Structure, chemistry, and biological activity. In: Atta-ur-Rahman (Ed.), Studies in Natural Products Chemistry, 26 (Bioactive Natural Products, Part G), Elsevier, pp. 507–579.
4.
AminahNS, AchmadSA, AimiN, GhisalbertiEL, HakimEH, KitajimaM, SyahYM, TakayamaH. (2002) Diptoindonesin A, a new C-glucoside of ∊-viniferin from Shorea seminis (Dipterocarpaceae). Fitoterapia, 73, 501–507.
5.
SyahYM, AminahNS, HakimEH, KitajimaM, TakayamaH, AchmadSA. (2003) Two Oligostilbenoids cis- and trans-diptoindonesian B from Dryobalanops oblongifolia. Phytochemistry, 63, 913–917.
6.
Muhtadi, HakimEH, JuliawatyLD, SyahYM, AchmadSA, LatipJ, GhisalbertiEL. (2006) Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii (Dipterocarpaceae). Fitoterapia, 77, 550–555.
7.
SaroyobudionoH, JuliawatyLD, SyahYM, AchmadSA, HakimEH, LatipJ, SaidIM. (2008) Oligostilbenoids from Shorea gibbosa and their cytotoxic properties against P-388 cells. Journal of Natural Medicines, 62, 195–198.
8.
Sahidin, HakimEH, JuliawatyLD, SyahYM, DinLB, GhisalbertiEL, LatipJ, SaidIM, AchmadSA. (2005) Cytotoxic properties of oligostilbenoids from the tree bark of Hopea dryobalanoides. Zeitschrift für Naturforschung, 60c, 723–727.
9.
AtunS, AchmadSA, NiwaM, ArianingrumR, AznamN. (2006) Oligostilbenoids from Hopea mengarawan (Dipterocarpaceae). Biochemical Systematic and Ecology, 34, 642–644.
10.
Bate-SmithEC, WhitmoreTC. (1959) Chemistry and taxonomy in the Dipterocarpaceae. Nature, 184, 795–796.
11.
SoekamtoNH, AchmadSA, GhisalbertiEL, HakimEH, SyahYM. (2003) Artoindonesianins X and Y, two isoprenylated 2-arylbenzofurans from Artocarpus fretessi (Moraceae). Phytochemistry, 64, 831–834.
12.
TanakaT, ItoT, IdoY, NakayaK-I, IinumaM, ChelladuraiV. (2001) Hopeafuran and a C-glucosyl resveratrol isolated from stem wood of Hopea utilis. Chemical and Pharmaceutical Bulletin, 49, 785–787.
13.
TanakaT, ItoT, IdoY, SonT-K, NakayaK, IinumaM, OhyamaM, ChelladuraiV. (2000) Stilbenoids in the stem bark of Hopea parviflora. Phytochemistry, 53, 1015–1019.
14.
DiyasenaMNC, SotheeswaranS, SurendrakumarS, BalasubramanianS, BokelM, KrausW. (1985) Balanocarpol, a new polyphenol from Balanocarpus zeylanicus (Trimen.) and Hopea jucunda (Thw.). Journal of the Chemical Society, Perkin Transactions1, 1807–1809.
15.
OshimaY, UenoY, HikinoH, YangLL, YenKY. (1990) Ampelopsins A, B and C, new oligostilbenes of Ampelopsis brevipedunculata var. hancei. Tetrahedron, 46, 5121–5126.
16.
PryceRJ, LangcakeP. (1977) (-)-α-Viniferin: an antifungal resveratrol trimer from Grapevines. Phytochemistry, 16, 1452–1454.
17.
WeberJFF, WahabIA, MarzukiA, ThomasNF, KadirAA, HadiAHA, AwangK, LatiffAA, RichomeP, DelaunayJ. (2001) Heimiol A, a new dimeric stilbenoid from Neobalanocarpus heimii. Tetrahedron Letters, 42, 4895–4897.
18.
TanakaT, ItoT, NakayaK, IinumaM, RiswanS. (2000) Oligostilbenoids in the stem bark of Vatica rassak. Phytochemistry, 54, 63–69.
19.
ItoJ, NiwaM, OshimaY. (1997) A new hydroxystilbene tetramer named isohopeaphenol from Vitis vinifera ‘Kyohou’. Heterocycles, 45, 1809–1813.