The EtOAc and n-BuOH extracts of Inga fendleriana inhibited Gram-positive, but not Gram-negative bacteria; a narrow spectrum of activity against Staphylococcus epidermidis was detected. The MIC values of the extracts ranged from 125 to 850 μg/mL. Quercetin 3-methylether, myricetin 3-O-rhamnoside and tricetin showed antibacterial activity against the same bacterial strains with MICs in the range from 31 to 250 μg/mL. In time-kill kinetic studies, the flavonoids showed bactericidal effects at the concentrations corresponding to four times the MICs.
BarkerKF. (1999) Antibiotic resistance: a current perspective. British Journal of Clinical Pharmacology, 48, 109–124.
2.
ChambersHF. (2001) The changing epidemiology of Staphylococcus aureus?. Emerging Infectious Diseases Journal7, 178–182.
3.
NormarkBH, NormarkS. (2002) Evolution and spread of antibiotic resistance. Journal of Internal Medicine, 252, 91–106.
4.
BasileA, SorboS, GiordanoS, RicciardiL, FerraraS, MonetanoD, CastaldoCapobianchi R, VuottoML, FerraraL. (2000) Antibacterial and allelopathic activity of extract from Castanea sativa leaves. Fitoterapia, 71, S110–S116.
5.
BisignanoG, SanogoR, MarinoA, AquinoR, D'AngeloV, GermanòMP, De PasqualeR, PizzaC. (2000) Antimicrobial activity of Mitracarpus scaber extract and isolated constituents. Letters in Applied Microbiology, 30, 105–108.
6.
Puupponen-PimiaR, NohynekL, MeierC, KahkonenM, HeinonenM, HopiaA, Oksman-CaldenteyKM. (2001) Antimicrobial properties of phenolic compounds from berries. Journal of Applied Microbiology, 90, 494–507.
7.
SavatA, AntonacciL, FortunatoRH, SuarezEY, GodoyHM. (2001) Screening of some plants from northern Argentina for their antimicrobial activity. Letters in Applied Microbiology, 32, 293–297.
8.
UrzaA, MendozaL. (2003) Antibacterial activity of fresh flower heads of Chrysantemum coronarium. Fitoterapia74, 606–608.
9.
MartiniND, KaterereDRP, EloffJN. (2004) Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae). Journal of Ethnopharmacology, 93, 207–212.
10.
PistelliL, BertoliA, MorelliI, MenichiniF, MusmannoRA, Di MaggioT, CoratzaG. (2005) Chemical and antibacterial evaluation of Hypericum triquetrifolium Turra. Phytotherapy Research, 19, 787–791.
11.
SatoM, FujiwaraS, TsuchiyaH, FujiiT, IinumaM, TosaH, OhkawaY, (1996) Flavones with antibacterial activity against cariogenic bacteria. Journal of Ethnopharmacology, 54, 171–176.
12.
HavsteenB (1983) Flavonoids, a class of natural products of high pharmacological potency. Biochemical Pharmacology, 32, 1141–1148.
13.
EbelJ, GrisebachH (1988) Defence strategies of soybean against fungus Phytophthora megasperma f. sp. glycinea: a molecular analysis. TIBS (Trends in Biochemical Sciences), 13, 23–27.
14.
PenningtonTD, ReveloN. (1997) In The Genus Inga. London: Royal Botanic Gardens Kew. pp. 610–613.
15.
HarborneJB. (1997) In The Genus Inga, Botany. London: Royal Botanic Gardens Kew. pp. 71–89.
16.
KiteGC. (1997) In The genus Inga Botany. London: Royal Botanic Gardens Kew. pp. 35–70.
VivotE, MuñozJD, CruañesMC, TapiaMJ, SchmedaHirschmann G, MartinezE, Di SapioO, GattusoM, ZacchinoS. (2001) Inhibitory activity of xanthine-oxidase and superoxide scavenger properties of Inga verna subsp. affinis. Its morphological and micrographic characteristics. Journal of Ethnopharmacology, 76, 65–71.
ZhongXN, OtsukaH, IdeT, HirataE, TakushiA, TakedaY. (1997) Three flavonol glycosides from leaves of Myrsine seguinii. Phytochemistry46, 943–946.
23.
AmsterdamD (1996) Susceptibility testing of antimicrobials in liquid media. In Antibiotics in Laboratory Medicine.LorianV. (Ed.)., Williams & Wilkins, 52–111.
24.
National Committee for Clinical Laboratory Standars. (2003) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, Approved Standard 6th ed. NCCLS document. M07 –A6. National Committee for Clinical laboratory Standards, Wayne, PA.
