Bursera grandifolia and other related species have been used in traditional herbal medicine in Mexico and other Latin American countries for their analgesic, antipyretic and anti-inflammatory properties. From the chloroform extract of leaves of B. grandifolia, a substance was isolated and identified as phenacetin, a well known compound with widely tested analgesic and antipyretic properties. The structural identity of the compound was elucidated on the basis of chemical and spectroscopic evidence and by comparison with an authentic sample.
MartínezM. (1959) Plantas Útiles de la flora mexicana. Ediciones Botas, México178–409.
2.
NogueraB, DíazE, GarcíaMV, San FelicianoA, López-PérezJL, IsraelA. (2004) Antiinflammatory activity of leaf extract and fractions of Bursera simaruba (L.) Sarg. (Burseraceae). Journal of Ethnopharmacology, 92129–133.
3.
CamporeseA, BalickMJ, ArvigoR, EspositoRG, MorsellinoN, De SimonaF, TubazoA. (2003) Screening of antibacterial activity of medicinal plants from Belize (Central America). Journal of Ethnopharmacology, 87103–107.
4.
YasunakaK, AbeF, NagayamaA, OkabeH, Lozada-PérezL, López-VillafrancoE, EstradaMuñiz E, AguilarA, Reyes-ChilapaR. (2005) Antibacterial activity of crude extracts from Mexican medicinal plants and purified coumarins and xanthones. Journal of Ethnopharmacology, 97293–299.
5.
FreiB, BaltisbergerM, SticherO, HeinrichM. (1998) Medical ethnobotany of the Zapotecs of the Isthmus-Sierra (Oaxaca, Mexico): Documentation and assessment of indigenous uses. Journal of Ethnopharmacology, 62149–165.
6.
Peraza-SanchezSR, Pena-RodriguezLM. (1992) Isolation of picropolygamain from the resin of Bursera simaruba. Journal of Natural Products, 551768–1771;
7.
Peraza-SanchezSR, Salazar-AguilarNE, Pena-RodriguezLMJ. (1995) A new triterpene from the resin of Bursera simaruba. Journal of Natural Products, 58271–274;
AbadMJ, BermejoP, CarreteroE, Martinez-AcitoresC, NogueraB, VillarA. (1996) Antiinflammatory activity of some medicinal plant extracts form Venezuela. Journal of Ethnopharmacology, 5563–68;
10.
CarreteroME, López-PérezJL, AbadMJ, BermejoP, TilletS, IsraelA, NogueraPB. (2008) Preliminary study of the anti-inflamatory activity of hexane extract and fractions from Bursera simaruba (Linn.) Sarg. (Burseraceae) leaves. Journal of Ethnopharmacology, 11611–15.
11.
SyamasundarKV, MallavarapuGR. (1995) Two triterpenoid lactones from the resin of Bursera delpechiana. Phytochemistry, 40337–339.
12.
BarreiraES, MonteFJQ, Braz-FilhoR. (1996) A new furanosesquiterpene from Bursera leptophloeos. Natural Product Letters, 8285–289.
13.
SouzaMP, MachadoMIL, Braz-FilhoR. (1989) Six flavonoids from Bursera leptophloeos. Phytochemistry, 282467–2470.
14.
JoladSD, WiedhopfRM, ColeJR. (1977) Cytotoxic agents from Bursera morelensis (Burseraceae): deoxypodophyllotoxin and a new lignan, 5′-desmethoxydeoxypodophyllotoxin. Journal of Pharmaceutical Sciences, 66892–893.
das GraçasLopes Cito AM, Arújo deSouza A, DantasLopes JA, ChavesME, Batista daCosta F, Alves deSousa SA, de Moura doAmaral MP. (2003) Resina de Protium heptaphyllum March (Burseraceae): Conposição química do óleo esencial e avaliação citotoxica frente a Artemia salina Leach. Anais da Associação Brasileira de Química, 5274–76.
17.
RaoVS, MaiaJL, OliveiraFA, LemosThelma LG, ChavesMH, SantosFlA. (2007) Composition and antinociceptive activity of the essential oil from Protium heptaphyllum resin. Natural Product Communications, 21199–1202;
18.
BandeiraPN, FonsecaAM, CostaSMO, LinsMUDS, PessoaODL, MonteFJQ, NogueiraNAP, LemosTLG (2006) Antimicrobial and Antioxidant Activities of the Essential Oil of Resin of Protium heptaphyllum. Natural Product Communications, 1117–120.
19.
PouchertCJ. (1985) Aldrich Library of FT-IR Spectra, Vol. 2, Aldrich Chemical Co., Inc.: Milwaukee, WI.359A p.;
20.
PouchertCJ, BehnkeJ. (Eds.) (1993) Aldrich Library of 13C and 1H FT-NMR Spectra, Vol. 2, Aldrich Chemical Co., Inc.: Milwaukee, WI.1366A p.;
