A new phenolic glycoside and three known compounds were isolated from the seeds of Cucurbita moschata. The structures of the new compound was elucidated as phenylcarbinyl 5-O-(4-hydroxy)benzoyl-β-D-apiofuranosyl (1→2)-β-D-glucopyranoside on the basis of spectroscopic analysis and chemical evidence. Three known compounds were identified as 1-O-benzyl[5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside 2, cucurbitosides C 3 and A 4, by comparison of the spectral data with reported data. Compound 2 was isolated from this plant for the first time.
(a) Shanghai Scientific Technological Publisher (eds.) (1985) Zhong hua ben cao.Shanghai Science and Technology Press, Shanghai, 529–529
2.
(b) (a) LiY, ZhaoLY, HuangN, ZhengYT, YangYP, LiXL. (2008) Two new phenolic glycosides from viscum articulatum.Molecules, 13, 2500–2508
3.
(c) KoikeK, LiW, LiuLJ, HataE, NikaidoT. (2005) New phenolic glycosides from the seeds of Cucurbita moschata. Chemical & Pharmaceutical Bulletin, 53, 225–228.
4.
(a) HaraS, OkabeH, MihashiK. (1987) Gas-liquid chromatographic separation of aldose enantiomers as trimethylsilyl ethers of methyl 2-(polyhydroxyalkyl)-thiazolidine-4(R)-carboxylates. Chemical and Pharmaceutical Bulletin, 35, 501–506
5.
(b) KitagawaL, HoriK, SakagamiM, HashiuchiF. Yoshikawa M, Ren J. (1993) Saponin and sapogenol. XLIX. On the constituents of the roots of Glycyrrhiza inflate Batalin from Xinjiang, China. Characterization of two sweet oleanane-type triterpene oligoglycosides, Apioglycyrrhizin and Araboglycyrrhizin. Chemical & Pharmaceutical Bulletin, 41, 1350–1357.
