A new styrylpyrone, 6-(7-hydroxy-8-methoxystyryl)-4-methoxypyran-2-one (1), together with two known styrylpyrones, 6-(7,8-epoxystyryl)-4-methoxypyran-2-one (2) and 6-(7,8-dihydroxystyryl)-4-methoxypyran-2-one (3) were isolated from the stem bark of Sanrafaelia ruffonammari Verdc. 6-(7,8-Epoxystyryl)-4-methoxypyran-2-one exhibited high inhibitory activity to interferon-γ-induced nitric oxide generation in RAW264.7 macrophages, whereas the other two showed no activity.
AhmadFB, TukolWA, OmarS, SharifAM. (1991) 5-Acetyl goniothalamin, A styryl dihydropyrone from Goniothalamus uvaroides.Phytochemistry, 30, 2430–2431.
6.
AdatyachaudhuryN, DasAK, DaskanugoP. (1976) Occurrence of 5,6-dehydrokawain and 7,8-epoxy-5,6-dehydrokawain in Didymocarpus aurentiana.Indian Journal of Chemistry, 14B, 909–911.
7.
DasAK, BhattacharyyaA, MitraSR. (1986) Occurrence of 7,8-epoxy-5,6-dehydrokawain in Didymocarpus podocarpus.Journal of the Indian Chemical Society, 63, 780–781.
8.
PizzolatiMG, LucianoC, MonacheFD. (2000) Styryl- and dihydrostyryl-2-pyrones derivatives from Polygala sabulosa.Phytochemistry, 55, 819–822.
9.
RosiMH, YoshidaM, MaiaJGS. (1997) Neolignans, styrylpyrones and flavonoids from an Aniba species. Phytochemistry, 45, 1263–1269.
LanY-H, ChangF-R, YangJ-L, ChangY-L, LeeS-J, WuY-C. (2003) Cytotoxic styrylpyrones from Goniothalamus amuyon.Journal of Natural Products, 66, 487–490.
13.
VerdcourtB. (1996) Garcia de Orta, Serial Botanica, Lisboa. 13, 43–48.
14.
AchenbachH, LoweE. (1997) Constituents of tropical medicinal plants. Part 85. Synthesis of 5,6-didehydrokawain trans-7,8–epoxide and related compounds. Natural Product Letters, 10, 79–85.
15.
ScottAI. (1964) Interpretation of the Ultraviolet Spectra of Natural Products. Pergamon Press, London/New York, p. 141.
16.
MurakamiA, TakahashiD, KoshimizuK, OhigashiH. (2003) Synergistic suppression of superoxide and nitric oxide generation from inflammatory cells by combined food factors. Mutation Research, 523–524, 151–161.
17.
MeyerBN, FerrigniNR, PutnamJE, JacobsenLB, NicholsDE, McLaughlinJL. (1982) Brine shrimp: A convenient general bioassay for active plant constituents. Planta Medica, 45, 31–34.
18.
KimOK, MurakamiA, NakamuraY, OhigashiH. (1998) Screening of edible Japanese plants for nitric oxide generation inhibitory activities in RAW 264.7 cells. Cancer Letters, 125, 199–207.
19.
KimOK, MurakamiA, NakamuraY, TakedaN, YoshizumiH, OhigashiH. (2000) Novel nitric oxide and superoxide generation inhibitors, persenone A and B, from avacado fruit. Journal of Agricultural and Food Chemistry, 48, 1557–1563.
