The total ethanolic extract (TEE) of Carduncellus eriocephalus Boiss. var. albiflora Gauba showed antioxidant, antihyperglycaemic, and antihyperlipidaemic activities, which were attributed to the n-butanol fraction (BF). Chemical investigation of the BF led to the isolation of a new flavonoid, kaempferol-3-O-β-D-galactopyranoside-6″-sulfate (16), and a phenyl propenyl glycoside, 1-β-D-glucopyranoside-3-phenyl-2-propenol (rosin) (6), which is reported for the first time in the family Asteraceae. Chrysoeriol (1), 3′-O-methylorobol (2), luteolin (3), quercetin (4), myricetin (5), kaempferol 3-O-α-L-arabinopyranoside (7), kaempferol 3-O-β-D-glucopyranoside (8), quercetin 3-O-β-D-glucopyranoside (12), luteolin 7-O-β-D-rutinoside (13), quercetin 3-O-β-D-rutinoside (14), apigenin 7-O-β-D-rutinoside (15), and 3,5-dicaffeoylquinic acid (17) were isolated for the first time from the genus Carduncellus, in addition to apigenin 7-O-β-D-glucopyranoside (9), chryseriol 7-O-β-D-glucopyranoside (10) and luteolin 7-O-β-D-glucopyranoside (11), which have been previously reported for C. eriocephalus.
