The chemical composition of the essential oil of Saccocalyx satureioides Coss. et Dur. (Lamiaceae) was analyzed by chiral and achiral GC/MS and 42 components were identified. The main constituents were (+)-α-terpineol (35.9%), thymol (15.6%) and borneol (12.4%). The in vitro antibacterial and antifungal activities of the essential oil were assessed by the disc diffusion method, and were significant on the six microorganisms tested. A moderate inhibitory activity against hepatitis C virus polymerase was also evidenced.
QuezelP, SantaS. (1963) Nouvelle flore de l'Algérie et des régions désertiques méridionales. Tome II, Editions du Centre National de la Recherche Scientifique, Paris.
2.
LaouerH, DahiaM, BelkhiriA, ShakerAN. (1996) Usages des plantes médicinales dans le Hodna. Santé plus: plantes médicinales et phytothérapie, 51, 15–19.
3.
CarsonCF, RileyTV. (1995) Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia. Journal of Applied Bacteriology, 78, 264–269.
4.
LattaouiN, Tantaoui-ElarakiA. (1994) Individual and combined antibacterial activity of the main components of three thyme essential oils. Rivista Italiana EPPOS, 13, 13–19.
5.
DidryN, DubreuilL, PinkasM. (1993) Antibacterial activity of thymol, carvacrol and cinnamaldehyde alone or in combination. Pharmazie, 48, 301–304.
6.
KiskóG, RollerS. (2005) Carvacrol and p-cymene inactivate Escherichia coli O157:H7 in apple juice. BioMedCentral Microbiology, 5, 36.
7.
UnluM, DafereraD, DonmezE, PolisiouM, TepeB, SokmenA. (2002) Composition and the in vitro antimicrobial activities of the essential oils of Achillea setacea and Achillea teretifolia (Compositae). Journal of Ethnopharmacology, 83, 117–121.
8.
UzelA, GuvensenA, CetinE. (2004) Chemical composition and antimicrobial activity of the essential oils of Anthemis xylopoda O. Schwarz from Turkey. Journal of Ethnopharmacology, 95, 151–154.
9.
FilipowiczN, KaminskiM, KurlendaJ, AsztemborskaM, OchockaJR. (2003) Antibacterial and antifungal activity of juniper berry oil and its selected components. Phytotherapy Research, 17, 227–231.
10.
OnawunmiGO, YisakWA, OgunlanaEO. (1984) Antibacterial constituents in the essential oil of Cymbopogon citratus (DC.) Stapf. Journal of Ethnopharmacology, 12, 279–286.
11.
SonboliA, EftekharF, YousefzadiM, KananiMR. (2005) Antibacterial and chemical composition of the essential oil of Grammosciadium platycarpum Boiss. from Iran. Zeitschrift für Naturforschung, 60c, 30–34.
12.
FaleiroML, MiguelMG, LadeiroF, VenancioF, TavaresR, BritoJC, FigueiredoAC, BarrosoJG, PedroLG. (2003) Antimicrobial activity of essential oils isolated from Portuguese endemic species of Thymus. Letters in Applied Microbiology, 36, 35–40.
13.
BurtS. (2004) Essential oils: their antibacterial properties and potential applications in foods—a review. International Journal of Food Microbiology, 94, 223–253.
14.
MoureyA, CanilacN. (2002) Anti-Listeria monocytogenes activity of essential oils components of conifers. Food Control, 13, 289–292.
15.
HammerKA, CarsonCF, RileyTV. (1999) Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86, 985–990.
16.
Boelens Aroma Chemical Information Service (BACIS). (1999) ESO 2000, The Complete Database of Essential Oils. Leffingwell and Associates publisher, Georgia, USA.
17.
JoulainD, KönigWA. (1998) The Atlas of Spectral Data of Sesquiterpene Hydrocarbons. E.B.-Verlag, Hamburg, Germany.
18.
JoulainD, KonigWA, HochmuthDH. (2001) Terpenoids and Related Constituents of Essential Oils. MassFinder 2.1, Hamburg, Germany.
19.
McLaffertyFW, StauferDB. (1989) The Wiley NBS Registry of Mass Spectral Data. Wiley, New York.
20.
SeliskoB, DutartreH, GuillemotJC, DebarnotC, BenarrochD, KhromykhA, DesprèsP, EgloffMP, CanardB.Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases. Virology, in press.
21.
DutartreH, BorettoJ, GuillemotJC, CanardB. (2005) A relaxed discrimination of 2′-O-methyl-GTP relative to GTP between de novo and elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B. Journal of Biological Chemistry, 280, 6359–6368.
