The essential oils of the barks of Croton monteverdensis Huft and C. niveus Jacq. (Euphorbiaceae) from Monteverde, Costa Rica, were isolated by hydrodistillation in yields of 0.03% and 0.10%, respectively. The chemical composition of the oils was determined by GC–MS. The most abundant essential oil components of C. monteverdensis were α-pinene (17.1%), β-pinene (10.5%), and linalool (8.3%), while C. niveus bark oil was made up largely of α-pinene (14.4%), 1,8-cineole (11.6%), and borneol (8.5%). The major components account for the fragrances and are consistent with the traditional medicinal uses of these plants.
GentryAH. (1996) A Field Guide to the Families and Genera of Woody Plants of Northwest South America (Colombia, Ecuador, Peru). University of Chicago Press, Chicago, Illinois.
2.
SchultesRE, RaffaufRF. (1990) The Healing Forest, Medicinal and Toxic Plants of the Northwest Amazonia. Dioscorides Press, Portland, Oregon.
3.
Hiruma-LimaCA, GraciosoJS, RodríquezJA, HaunM, NunesDS, Souza BritoARM. (2000) Gastroprotective effect of essential oil from Croton cajucara Benth. (Euphorbiaceae). Journal of Ethnopharmacology, 69, 229–234.
4.
Hiruma-LimaCA, GraciosoJS, BighettiEJB, Grassi-KassisseDM, NunesDS, Souza BritoARM. (2002) Effect of essential oil obtained from Croton cajucara Benth. on gastric ulcer healing and protective factors of the gastric mucosa. Phytomedicine, 9, 523–529.
5.
CraveiroAA, AndradeCHS, MatosFJA, de AlencarJW. (1978) Anise-like flavor of Croton aff. zehntneri Pax et Hoffm. Journal of Agricultural and Food Chemistry, 26, 772–773.
6.
Coelho-de-SouzaAN, BarataEI, MagalhãesPJC, LimaCC, Leal-CardosoJH. (1997) Effects of the essential oil of Croton zehntneri, and its constituent estragole on intestinal smooth muscle. Phytotherapy Research, 11, 299–304.
7.
BatatinhaMJM, de Souza-SpinosaH, BernardiMM. (1995) Croton zehntneri: possible central nervous system effects of the essential oil in rodents. Journal of Ethnopharmacology, 45, 53–57.
8.
Coelho-de-SouzaAN, CriddleDN, Leal-CardosoJH. (1998) Selective molulatory effects of the essential oil of Croton zehntneri on isolated smooth muscle preparations of the Guinea-pig. Phytotherapy Research, 12, 189–194.
9.
LahlouS, Leal-CardosoJH, MagalhãesPJC, Coelho-de-SouzaAN, DuarteGP. (1999) Cardiovascular effects of the essential oil of Croton nepetaefolius in rats: role of the autonomic nervous system. Planta Medica, 65, 553–557.
10.
MagalhãesPJC, CriddleDN, TavaresRA, MeloEM, MotaTL, Leal-CardosoJH. (1998) Intestinal myorelaxant and antispasmodic effects of the essential oil of Croton nepetaefolius and its constituents cineole, methyl-eugenol and terpineol. Phytotherapy Research, 12, 172–177.
11.
BlockS, FlaminiG, BrkicD, MorelliI, Quentin-LeclercqJ. (2006) Analysis of the essential oil from leaves of Croton zambesicus Muell. Arg. growing in Benin. Flavour and Fragrance Journal, 21, 222–224.
12.
MortonJF. (1981) Atlas of Medicinal Plants of Middle America, Vol. 1. Thomas Publishing, Springfield, Illinois.
13.
MecciaG, RojasLB, RosqueteC, San FelicianoA. (2000) Essential oil of Croton ovalifolius Vahl from Venezuela. Flavour and Fragrance Journal, 15, 144–146.
14.
HaberWA, ZuchowskiW, BelloE. (1996) An Introduction to Cloud Forest Trees, Monteverde, Costa Rica. La Nacion, San Jose, Costa Rica.
15.
RojasET, Rodriguez-HahnL. (1978) Nivenolide, a diterpene lactone from Croton niveus. Phytochemistry, 17, 574–575.
16.
FekamBoyom F, KeumedjioF, JazetDongmo PM, NgadjuiBT, AmvamZollo PH, MenutC, BessiereJM. (2002) Essential oils from Croton zambesicus Muell. Arg. growing in Cameroon. Flavour and Fragrance Journal, 17, 215–217.
17.
LopesD, BizzoHR, SobrinhoAFS, PereiraMVG. (2000) Linalool-rich essential oil from leaves of Croton cajucara Benth. Journal of Essential Oil Research, 12, 705–708.
18.
CraveiroAA, RodriguesAS, AndradeCHS, MatosFJA, AlencarJW, MachadoMIL. (1981) Volatile constituents of Brazilian Euphorbiaceae. Genus Croton. Journal of Natural Products, 44, 602–608.
19.
SuárezAI, VásquezLJ, ManzanoMA, CompagnoneRS. (2005) Essential oil composition of Croton cuneatus and Croton malambo growing in Venezuela. Flavour and Fragrance Journal, 20, 611–614.
20.
LetiziaCS, CocchiaraJ, LalkoJ, ApiAM. (2003) Fragrance material review on linalool. Food Chemistry and Toxicology, 41, 943–964.
21.
BarocelliE, CalcinaF, ChiavariniM, ImpicciatoreM, BruniR, BianchiA, BallabeniV (2004) Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon “Grosso” essential oil. Life Science, 76, 213–233.
22.
Pardo de SantayanaM, BlancoE, MoralesR. (2005) Plants known as té in Spain: An ethno-pharmaco-botanical review. Journal of Ethnopharmacology98, 1–19.
23.
MartinS, PadillaE, OceteMA, GalvezJ, JiménezJ, ZarzueloA. (1993) Anti-inflammatory activity of the essential oil of Bupleurum fruticescens. Planta Medica, 59, 533–536.
24.
JuergensUR, StöberM, VetterH. (1998) Inhibition of cytokine production and arachidonic acid metabolism by eucalyptol (1.8-cineole) in human blood monocytes in vitro. European Journal of Medical Research, 3, 508–510.
25.
SantosFA, RaoVS. (2000) Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytotherapy Research, 14, 240–244.
26.
ParkTJ, ParkYS, LeeTG, HaH, KimKT. (2003) Inhibition of acetylcholine-mediated effects by borneol. Biochemical Pharmacology, 65, 83–90.
27.
GrangerRE, CampbellEL, JohnsonGAR. (2005) (+)- and (-)-borneol: efficacious positive modulators of GABA action at human recombinant α1β2γ2L GABAA receptors. Biochemical Pharmacology, 69, 1101–1111.
28.
AdamsRP (1995) Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. Allured Publishing, Carol Stream, Illinois.
29.
AdahchourM, van SteeLLP, BeensJ, VreulsRJJ, BatenburgMA, BrinkmanUAT. (2003) Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection for the trace analysis of flavour compounds in food. Journal of Chromatography, A, 1019, 157–172.
30.
YayliN, YaşarA, Güleç, UstaA, KolayliS, CoşkunçelebiK, KaraoğluŞ. (2005) Composition and antimicrobial activity of essential oils from Centaurea sessilis and Centaurea armena. Phytochemistry, 66, 1741–1745.
31.
PaoliniJ, CostaJ, BernardiniAF (2005) Analysis of the essential oil from aerial parts of Eupatorium cannabinum subsp. corsicum (L.) by gas chromatography with electron impact and chemical ionization mass spectrometry. Journal of Chromatography, A, 1076, 170–178.
32.
OngPKC, AgreeTE, LavinEH. (1998) Characterization of volatiles in rambutan fruit (Nephelium lappaceum L.)Journal of Agricultural and Food Chemistry, 46, 611–615.
33.
NickavarB, MojabF, AsgarpanahJ. (2005) Volatile composition of the essential oil of Salvia hypoleuca Benth. International Journal of Aromatherapy, 15, 51–53.