This article provides insights into how the authors developed the Solitaire™ FR revascularization device and associated procedure including commentary on the mechanism of revascularization and future of device development in this area. The article is intended to give research-minded physicians a view into the device development world by sighting examples of this novel device for revascularizing patients with acute ischemic stroke.
Lloyd-JonesDAdamsRCarnethonM. Heart disease and stroke statistic 2009 update. A Report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009; 119(3): e21–e181.
2.
SmithWSSungGStarkmanS. Safety and efficacy of mechanical embolectomy in acute ischemic stroke results of the MERCI trial. Stroke. 2005; 36: 1432–1438.
3.
SmithWSSungGSaverJ. Mechanical thrombectomy for acute ischemic stroke: Final results of the Multi MERCI trial. Stroke2008; 39: 1205–1212. Epub 2008 Feb 28.
4.
NatarajanSKKarmonYSiddiquiAH. Intracranial stent-assisted revascularization for acute ischemic stroke. Vasc Dis Manage. 2009; 6 (11/12): 177–185. Epub 2009 Nov 06.
5.
NogueiraRGSchwammLHHirschJA. Endovascular approaches to acute stroke, Part 1: Drugs, devices, and data. Am J Neuroradiol. 2009; 20: 649–661.
6.
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. New Eng J Med.1995; 333(24): 1581–1587.
7.
The Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial. Safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke. 2009; 40: 2761–2768.
