There are many reasons for patients infected with human immunodeficiency virus (HIV) to develop cerebrovascular disease. The HIV virus itself however may be a cause of vessel wall pathology. We present a clinical and pathological study of a patient who was HIV positive and presented with a subarachnoid haemorrhage. Cerebral angiography and later histology confirm that there was extensive vessel wall injury with dissection and a false aneurysm of the right middle cerebral artery.
KureKParkYd: Immunohistochemical localization of an HIV epitope in cerebral aneurysmal arteriopathy in pediatric acquired immunodeficiency syndrome (AIDS). Pediatr Pathol9: 655–667, 1989.
5.
TaylorALeFeuvreD: Arterial dissection and subarachnoid haemorrhage in HIV infected patients. A report of 3 cases. Interventional Neuroradiology10: 137–141, 2004.
6.
ColeJWPintoAN: Acquired immunodeficiency syndrome and the risk of stroke. Stroke35: 51–56, 2004.
7.
MhetaNReillyM: Atherosclerotic cardiovascular disease risk in the HAART treated HIV1 population. HIV Clin Trials6: 5–24, 2005.
8.
BlumAHadasV: Viral load of the human immunodeficiency virus could be an independent risk factor for endothelial dysfunction. Clin Cardiol28: 149–153, 2005.
9.
PatsalidesADWoodLV: Cerebrovascular Disease in HIV-Infected Pediatric Patients: Neuroimaging Findings. American Journal of Roentgenology179: 999–1003, 2002.
10.
ShenYNFrenkelEP: Thrombosis and a hypercoagulable state in HIV-infected patients. Clin Appl Thromb Hemost, 10: 277–280, 2004.
11.
SilvestriniMFlorisR: Spontaneous subarachnoid haemorrhage in an HIV patient. Ital J Neurol Sci11: 493–495, 1990.
12.
JoshiVVPawelB: Arteriopathy in children with acquired immune deficiency syndrome. Pediatr Pathol7: 261–275, 1987.
13.
TakabaMEndoS: Vasa Vasorum of the intracranial arteries. Acta Neurochir140: 411–416, 1998.
14.
ConnollyESHuangJGoldmanJE: Immunohistochemical detection of intracranial vasa vasorum: A human autopsy study. Neurosurgery38: 789–793, 1996.
15.
AydinF: Do human intracranial arteries lack vasa vasorum? A comparative immunohistochemical study of intracranial and systemic arteries. Acta Neuropathol96: 22–28, 1998.