Radical prostatectomy commonly results in urinary, sexual, and bowel dysfunction that bothers men and may lead to depressive symptomatology (hereafter depression) that occurs at a rate 4 times greater for men with prostate cancer than healthy counterparts. The purpose of this study was to assess depressive symptoms in men shortly after radical prostatectomy and to identify associated risk factors. Seventy-two men were interviewed 6 weeks after surgery. Measured were depression (Geriatric Depression Scale), self-efficacy (Stanford Inventory of Cancer Patient Adjustment), social support (Modified Inventory of Socially Supportive Behaviors), physical and emotional factors (UCLA Prostate Cancer Index), and social function (SF-36 subscale). Results indicate that men with high self-efficacy and less sexual bother were 45% and 55% less likely to have depressive symptoms, respectively. Findings from this study add to the limited amount of information on the complex relationship between prostate cancer treatment and depression in men.
Dalkin, B.L., Wessells, H., & Cui, H. (2003). A national survey of urinary and health related quality of life outcomes in men with an artificial urinary sphincter for post-radical prostatectomy incontinence. Journal of Urology, 169, 237-239.
8.
Depression and erectile dysfunction: Which is the cart, which is the horse? (2004). Harvard Men's Health Watch, 9, 7-8.
9.
Ertan, F.S., Ertan, T., Kiziltan, G., & Uygucgil, H. (2005). Reliability and validity of the Geriatric Depression Scale in depression in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 76, 1445-1447.
10.
Hedestig, O., Sandman, P.O., Tomic, R., & Widmark, A. (2005). Living after radical prostatectomy for localized prostate cancer: A qualitative analysis of patient narratives. Acta Oncology, 44, 679-686.
11.
Heisel, M.J., Flett, G.L., Duberstein, P.R., & Lyness, J.M. (2005). Does the Geriatric Depression Scale (GDS) distinguish between older adults with high versus low levels of suicidal ideation? American Journal of Geriatric Psychiatry, 13, 876-883.
12.
Hosmer, D.W., & Lemeshow, S. (2000). Applied logistic regression (2nd ed). New York: John Wiley.
13.
Korfage, I.J., Essink-Bot, M.L., Borsboom, G.J., Madalinska, J.B., Kirkels, W.J., Habbema, J.D., et al. (2005). Five-year follow-up of health-related quality of life after primary treatment of localized prostate cancer. International Journal of Cancer, 116, 291-296.
14.
Korfage, I.J., Essink-Bot, M.L., Janssens, A.C., Schroder, F.H., & de Koning, H.J. (2006). Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up. British Journal of Cancer, 94, 1093-1098.
15.
Krause, N., & Markides, K. (1990). Measuring social support among older adults. International Journal of Aging & Human Development, 30, 37-53.
16.
Lev, E.L. (1997). Bandura's theory of self-efficacy: Applications to oncology. Scholarly Inquiry for Nursing Practice: An International Journal, 11, 21-43.
17.
Litwin, M.S., Hays, R.D., Fink, A., Ganz, P.A., Leake, B., & Brook, R.H. (1998). The UCLA Prostate Cancer Index: Development, reliability, and validity of a health related-quality of life measure. Medical Care, 36, 1002-1012.
18.
Litwin, M.S., Sadetsky, N., Pasta, D.J., & Lubeck, D.P. (2004). Bowel function and bother after treatment for early stage prostate cancer: A longitudinal quality of life analysis from CaPSURE. Journal of Urology, 172, 515-519.
19.
Maddux, J.E., & Meier, L.J. (1995). Self-efficacy and depression. In J. E. Maddux (Ed.), Self-efficacy, adaptation, and adjustment: Theory, research, and application (pp. 143-169). New York: Plenum.
20.
National Institute of Mental Health. (2005 ). Men and depression. Bethesda, MD: National Institutes of Health.
21.
National Institute on Aging and National Cancer Institute. (2005). Age-related prostate growth: Biologic mechanisms (Rep. No. PA-02-116). Bethesda, MD: National Institutes of Health.
22.
Patrick, D.L., Ferketich, S.L., Frame, P.S., Harris, J.J., Hendricks, C.B., Levin, B., et al. (2003). National Institutes of Health State-of-the-Science Conference Statement: Symptom management in cancer: Pain, depression, and fatigue, July 15-17, 2002. Journal of the National Cancer Institute, 95, 1110-1117.
23.
Peduzzi, P., Concato, J., Kemper, E., Holford, T.R., & Feinstein, A.R. (1996). A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology, 49, 1373-1379.
24.
Resnick, M., & Thompson, I.M. (2000). Advanced therapy of prostate disease. Hamilton, Ontario, Canada: BC Decker.
25.
Robinson, J.D., & Turner, J. (2003). Impersonal, interpersonal, and hyperpersonal social support: Cancer and older adults. Health Communications, 15, 227-234.
26.
Rose, M.S., Koshman, M.L., Spreng, S., & Sheldon, R. (1999). Statistical issues encountered in the comparison of health-related quality of life in diseased patients to published general population norms: Problems and solutions. Journal of Clinical Epidemiology, 52, 405-412.
27.
Sheikh, J.I., & Yesavage, J.A. (1986). Geriatric depression scale (GDS) recent evidence and development of a shorter version. Clinical Gerontologist, 5, 165-173.
28.
Stanford, J.L., Feng, Z., Hamilton, A.S., Gilliland, F.D., Stephenson, R.A., Eley, J.W., et al. (2000). Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: The Prostate Cancer Outcomes Study. Journal of the American Medical Association , 283, 354-360.
29.
Steers, W.D., & Lee, K.S. (2001). Depression and incontinence. World Journal of Urology, 19, 351-357.
30.
Stevens, R.A., Mikat-Stevens, M., Flanigan, R., Waters, W.B., Furry, P., Sheikh, T., et al. (1998). Does the choice of anesthetic technique affect the recovery of bowel function after radical prostatectomy? Urology, 52, 213-218.
31.
Streiner, D.L. (2002). Breaking up is hard to do: The heart-break of dichotomizing continuous data. Canadian Journal of Psychiatry , 47, 262-266.
32.
Sugimori, H., Yoshida, K., Tanaka, T., Baba, K., Nishida, T., Nakazawa, R., et al. (2005). Relationships between erectile dysfunction, depression, and anxiety in Japanese subjects. Journal of Sexual Medicine, 2, 390-396.
33.
Telch, C. (1985). A comparison of coping skills instruction and support group counseling in alleviating psychological distress among cancer patients. Unpublished PhD dissertation, Stanford University .
34.
Underwood, B.R. (2006). Vardenafil improves comorbid erectile dysfunction and mild depression. Evidence Based Mental Health, 9, 77.
35.
Vittinghoff, E., & McCulloch, C.E. (2006). Relaxing the rule of ten events per variable in logistic and cox regression. American Journal of Epidemiology, 165, 710-718.
36.
Ware, J.E., Snow, K.K., Kosinski, M., & Gandek, B. (1993). SF-36 Health Survey: Manual and interpretation guide. Boston, MA: The Health Institute, New England Medical Center.
37.
Watson, A.J., Currie, I., Curran, S., & Jarvis, G.J. (2000). A prospective study examining the association between the symptoms of anxiety and depression and severity of urinary incontinence . European Journal of Obstetrics Gynecology and Reproductive Biology, 88, 7-9.
38.
Weber, B.A., Roberts, B.L., & McDougall, G.J. , Jr. (2000). Exploring the efficacy of support groups for men with prostate cancer. Geriatric Nursing, 21, 250-253.
39.
Weber, B.A., Roberts, B.L., Resnick, M., Deimling, G., Zauszniewski, J.A., Musil, C., et al. (2004). The effect of dyadic intervention on self-efficacy, social support, and depression for men with prostate cancer. Psychooncology, 13, 47-60.
40.
Wong, S.Y., Chan, D., Hong, A., Leung, P.C., & Woo, J. (2006). Depression and lower urinary tract symptoms: Two important correlates of erectile dysfunction in middle-aged men in Hong Kong, China. International Journal of Urology, 13, 1304-1310.
41.
Yesavage, J.A., Brink, T.L., Rose, T.L., Lum, O., Huang, V., Adey, M., et al. (1982). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, 17, 37-49.
