Intimal Hyperplasia: Prospects for Its Control in the Human

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1. Cox JL , Chiasson DA , Gotlieb Al : Stranger in a strange land. Prog Cardiovasc Dis 34:45-68, 1991.

2. Zwolak RM , Adams MC , Clowes AW : Kinetics of vein graft hyperplasia. J Vasc Surg 5:126-136, 1987.

3. Clowes AW , Geary R : Vascular biology-the new frontier. Cardiovasc Surg 2:301-307, 1994.

4. Clowes AW , Clowes MM , Fingerly J , et al: Regulation of smooth muscle cell growth in injured artery. J Cardiovasc Pharmacol 14:S12-S15, 1989.

5. Pickering JG , Weir L , Jekanowski J , et al: Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest 91:1469-1480, 1993.

6. Gordon D , Reidy MA , Benditt EP , et al: Cell proliferation in human coronary arteries. Proc Natl Acad Sci 87:4600-4604, 1990.

7. O'Brien ER , Alpers CE , Steward DK , et al: Proliferation in primary and restenotic coronary atherectomy tissue. Circ Res 73:223-231, 1993.

8. Linder V , Majack RA , Reidy MA : Basic fibroblast growth factor stimulates endothelial regrowth and proliferation in denuded arteries. J Clin Invest 85:2004-2008, 1990.

9. Clowes WA , Reidy MA , Clowes MM : Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium. Lab Invest 49:208-215, 1983.

10.

10. Clowes AW , Reidy MA , Clowes MM : Mechanisms of stenosis after arterial injury. Lab Invest 49:208-215, 1983.

11.

11. Han DKM , Haudenschild CC , Hong MK , et al: Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Path 147:267-277, 1995.

12.

12. Jackson CL , Reidy MA : Basic fibroblast growth factor: Its role in the control of smooth muscle cell migration. Am J Pathol 143:1024-1031, 1993.

13.

13. Reidy MA : Neointimal proliferation: The role of basic FGF on vascular smooth muscle cell proliferation. Thromb Haemost 70:172-176, 1993.

14.

14. Fingerle J , Johnson R , Clowes AW , et al: Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery. Proc Natl Acad Sci USA 86:8412-8416, 1989.

15.

15. Friedman RJ , Stemerman MB , Wenz B , et al: The effect of thrombocytopenia on experimental atherosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization. J Clin Invest 60:1191-1201,1977.

16.

16. Edelman ER , Karnovsky MJ : Contrasting effects of the intermittent and continuous administration of heparin in experimental restenosis. Circulation 89:770-776, 1994.

17.

17. Farhy RD , Carreter OA , Ho K-L , et al: Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation. Circ Res 72:1202-1210, 1993.

18.

18. Clowes AW , Clowes MM , Au YPT , et al: Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. Circ Res 67:61-67, 1990.

19.

19. Ferns GA , Raines EW , Sprugel KH , et al: Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253:1129-1132, 1992.

20.

20. Jawien A , Bowen-Pope DF , Linder V , et al: Plateletderived growth factor promotes smooth muscle cell migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest 89:507-511, 1992.

21.

21. Majesky MW , Lindner V , Twardzik DR , et al: Production of transforming growth factor beta during repair of arterial injury. J Clin Invest 88:904-910, 1991.

22.

22. Cercek B , Fishbein MC , Forrester JS , et al: Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation. Circ Res 66:1755-1760, 1990.

23.

23. Hansson GK , Jonasson L , Holm J , et al: Gamma interferon regulates vascular smooth muscle proliferation and la expression in vitro and in vivo. Circ Res 63:712-719, 1988.

24.

24. Loppnow H , Libby P : Functional significance of human vascular smooth muscle cell-derived interleukin 1 in paracrine and autocrine regulation pathways. Cell Res 198:283-290, 1992.

25.

25. Herrmann HC , Shunichiro O , Hozakowska E , et al: Inhibition of smooth muscle cell proliferation and experimental angioplasty. Restenosis by f-cyclodextrin tetradecasulfate. Arterioscler Thromb 13:924-931, 1993.

26.

26. Faggiotto A , Ross R , Harker L : Studies of hypercholesterolemia in the nonhuman primate. Arteriosclerosis 4:323-323, 1994.

27.

27. Snow AD , Bolender PP , Wight TN , et al: Heparin modulates the composition of the extracellular matrix domain surrounding arterial smooth muscle cells. Am J Pathol 137:313-330, 1990.

28.

28. Kohler TR , Jawien A : Flow affects development of intimal hyperplasia after arterial injury in rats. Arterioscler Thromb 12:963-971, 1992.

29.

29. Sumpio BE , Banes AJ : Response of porcine aortic smooth muscle cells to cyclic tensional deformation in culture. J Surg Res 44:696-701, 1988.

30.

30. Powell JS , Clozel JP , Muller RKM , et al: Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury. Science 245:186-188, 1989.

31.

31. Clowes AW , Karnovsky MJ : Suppression by heparin of smooth muscle cell proliferation in injured arteries. Nature 265:625-626, 1977.

32.

32. Huber KC , Schwartz RS , Edwards WD , et al: Effects of angiotensin converting enzyme inhibition on neointimal proliferation in a porcine coronary injury model. Am Heart J 125:695-701, 1993.

33.

33. Churchill DA , Siegel CO , Minor ST , et al: Enalapril in the prevention of restenosis following intracoronary intervention in a swine model. Coronary Artery Dis 4:461-467, 1993.

34.

34. Hanson SR , Powell JS , Dodson T , et al: Effects of angiotensin converting enzyme inhibition with cilazapril on intimal hyperplasia in injured arteries and vascular grafts in the baboon. Hypertension 18:70-76, 1991.

35.

35. Heyndrickz GR , MERCATOR Study Group : Angiotensin-converting enzyme inhibitor in a human model of restenosis. Basic Res Cardiol 88:169-182, 1993.

36.

36. MERCATOR Study Group : Does the new angiotensin converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR study: A multicenter, randomized, double-blind, placebo-controlled trial. Circulation 86:100-110, 1992.

37.

37. Ellis SG , Roubin GS , Wilentz J , et al: Effect of 18 to 24 hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty. Am Heart J 117:777-782, 1989.

38.

38. Edelman ER , Adams DH , Karnovsky MS : Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury. PNAS 87:3773-3777, 1990.

39.

39. Bachinsky WB , Barnathan ES , Liu H , et al: Sustained inhibition of intimal thickening: In vitro and in vivo effects of polymeric beta-cyclodextrin sulfate. J Clin Invest 96:2583-2592, 1995.

40.

40. Simons M , Edelman ER , DeKeyser JL , et al: Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature 359:67-70, 1992.

41.

41. Morishita R , Gibbons GH , Ellison KE , et al: Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc Natl Acad Sci USA 90:8474-8478, 1993.

42.

42. Chang MW , Barr E , Seltzer J , et al: Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science 267:518-522, 1995.

43.

43. Waksman R , Robinson KA , Crocker IR , et al: Intracoronary low-dose beta-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model. Circulation 92:3025-3031, 1992.

44.

44. Eton D , Ahn SS : Photodynamic Therapy of Intimal Hyperplasia. Pharmacologic Suppression of Intimal Hyperplasia. Austin and Georgetown: RG Landes Co, 1993.

45.

45. Ohno T , Gordon D , San H , et al: Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265:781-784, 1994.

46.

46. Lee SW , Trapnell BC , Rade JJ , et al: In vivo adenoviral vector-mediated gene transfer into balloon injured rat carotid arteries. Circ Res 73:797-807, 1993.

47.

47. Lemarchand P , Jones M , Yamada I , et al: In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ Res 72:1132-1138, 1993.

48.

48. Lynch CM , Clowes MM , Osborne WRA , et al: Longterm expression of human adenosine deaminase in vascular smooth muscle cells of rats: A model for gene therapy. Proc Natl Acad Sci 89:1138-1142, 1992.