A case of intrapericardial giant lymph node hyperplasia (localized hyaline-vascular variant of Castleman's disease) is reported. The large tumor was successfully removed, and at a twelve-year follow-up there are no signs of recurrence. This is the first case reported in the literature of an intrapericardial Castleman's disease localization. Embryologic, surgical, and prognostic implications of this finding are briefly discussed.
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