Eq5Dmap: A Command for Mapping between EQ-5D-3L and EQ-5D-5L

Abstract

In this article, we describe a new command, eq5dmap, for conditional prediction of the utility values of EQ-5D-5L (EQ-5D-3L) from observed or specified values of EQ-5D-3L (EQ-5D-5L) conditional on age and gender. Predictions can be made either from the five-item health descriptions or from the (exact or approximate) utility score. The prediction process is based on a joint statistical model of the two variants of EQ-5D that have been fit to alternative reference datasets (the National Data Bank for Rheumatic Diseases and a EuroQol Group coordinated data-collection study). The underlying model is a system of ordinal regressions with a flexible residual distribution specified as Gaussian or as a copula mixture. Use of the command is illustrated with an application that includes an investigation of the sensitivity of the mapping outcomes to the choice of reference dataset.