In 2005, Barthel, Royston, and Babiker presented a menu-driven Stata program under the generic name of ART (assessment of resources for trials) to calculate sample size and power for complex clinical trial designs with a time-to-event or binary outcome. In this article, we describe a Stata tool called ARTPEP, which is intended to project the power and events of a trial with a time-to-event outcome into the future given patient accrual figures so far and assumptions about event rates and other defining parameters. ARTPEP has been designed to work closely with the ART program and has an associated dialog box. We illustrate the use of ARTPEP with data from a phase III trial in esophageal cancer.
BarthelF. M.-S., BabikerA., RoystonP., and ParmarM. K. B.2006. Evaluation of sample size and power for multiarm survival trials allowing for non-uniform accrual, nonproportional hazards, loss to follow-up and cross-over. Statistics in Medicine25: 2521–2542.
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BarthelF. M.-S., RoystonP., and BabikerA.2005. A menu-driven facility for complex sample size calculation in randomized controlled trials with a survival or a binary outcome: Update. Stata Journal5: 123–129.
